DK319484A - Imidazol-2-ylthioalkansyrer, fremgangsmaade til deres fremstilling samt farmaceutiske praeparater indeholdende disse - Google Patents

Imidazol-2-ylthioalkansyrer, fremgangsmaade til deres fremstilling samt farmaceutiske praeparater indeholdende disse Download PDF

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Publication number
DK319484A
DK319484A DK319484A DK319484A DK319484A DK 319484 A DK319484 A DK 319484A DK 319484 A DK319484 A DK 319484A DK 319484 A DK319484 A DK 319484A DK 319484 A DK319484 A DK 319484A
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DK
Denmark
Prior art keywords
imidazol
acids
ylthioalcanic
procedure
preparation
Prior art date
Application number
DK319484A
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English (en)
Other versions
DK319484D0 (da
DK162439C (da
DK162439B (da
Inventor
Hans-Heiner Lautenschlaeger
Gerrit Prop
Helmut Wetzig
Original Assignee
Nattermann A & Cie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nattermann A & Cie filed Critical Nattermann A & Cie
Publication of DK319484D0 publication Critical patent/DK319484D0/da
Publication of DK319484A publication Critical patent/DK319484A/da
Publication of DK162439B publication Critical patent/DK162439B/da
Application granted granted Critical
Publication of DK162439C publication Critical patent/DK162439C/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/84—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
DK319484A 1983-07-02 1984-06-29 Imidazol-2-ylthioalkansyrer og derivater deraf, fremgangsmaader til deres fremstilling samt farmaceutiske praeparater indeholdende disse DK162439C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3323870 1983-07-02
DE19833323870 DE3323870A1 (de) 1983-07-02 1983-07-02 Neue imidazol-2-ylthioalkansaeuren und ihre derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate

Publications (4)

Publication Number Publication Date
DK319484D0 DK319484D0 (da) 1984-06-29
DK319484A true DK319484A (da) 1985-01-03
DK162439B DK162439B (da) 1991-10-28
DK162439C DK162439C (da) 1992-03-23

Family

ID=6202975

Family Applications (1)

Application Number Title Priority Date Filing Date
DK319484A DK162439C (da) 1983-07-02 1984-06-29 Imidazol-2-ylthioalkansyrer og derivater deraf, fremgangsmaader til deres fremstilling samt farmaceutiske praeparater indeholdende disse

Country Status (9)

Country Link
US (1) US4654358A (da)
EP (1) EP0130526B1 (da)
JP (1) JPS6045563A (da)
AT (1) ATE31300T1 (da)
DE (2) DE3323870A1 (da)
DK (1) DK162439C (da)
GR (1) GR82111B (da)
IE (1) IE57729B1 (da)
ZA (1) ZA844835B (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3504678A1 (de) * 1985-02-12 1986-08-14 A. Nattermann & Cie GmbH, 5000 Köln Neue imidazolyl-oxyalkansaeuren und -thioalkansaeuren, ihre derivate und verfahren zu ihrer herstellung
DE3504677A1 (de) * 1985-02-12 1986-08-14 A. Nattermann & Cie GmbH, 5000 Köln Neue imidazol-2-yloxyalkansaeuren und ihre derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
JPS62257803A (ja) * 1986-05-02 1987-11-10 段谷産業株式会社 樹脂強化化粧板の製造方法
US4935438A (en) * 1987-12-29 1990-06-19 Smithkline Beckman Corporation Dopamine-β-hydroxylase inhibitors
NO890522L (no) * 1988-02-25 1989-08-28 Bayer Ag Substituerte imidazolinoner og imidazolinthioner.
US4900744A (en) * 1988-09-14 1990-02-13 E. I. Du Pont De Nemours And Company Antihypercholesterolemic 4,5-diaryl-2-substituted thioimidazoles
CA2003283A1 (en) * 1988-12-05 1990-06-05 C. Anne Higley Imidazoles for the treatment of atherosclerosis
US5166214A (en) * 1988-12-05 1992-11-24 Du Pont Merck Pharmaceutical Company Use of imidazoles for the treatment of atherosclerosis
EP0505481A1 (en) * 1989-12-12 1992-09-30 Rhone-Poulenc Sante 2-substituted 4,5-diphenyl-imidazoles
MX9203711A (es) * 1990-01-12 1992-07-01 Rhone Poulenc Rorer Sa Derivados de imidazol y composiciones farmaceuticas que los contienen.
GB9019838D0 (en) * 1990-09-11 1990-10-24 Smith Kline French Lab Compounds
US5179117A (en) * 1991-12-20 1993-01-12 Du Pont Merck Pharmaceutical Company Antihypercholesterolemic 2-substituted imidazoles
US5310748A (en) * 1992-05-11 1994-05-10 The Du Pont Merck Pharmaceutical Company Imidazoles for the treatment of atherosclerosis
US5364875A (en) * 1992-05-11 1994-11-15 The Du Pont Merck Pharmaceutical Company Imidazoles linked to bicyclic heterocyclic groups for the treatment of atherosclerosis
DE10222103A1 (de) * 2002-05-17 2003-11-27 Merckle Gmbh Chem Pharm Fabrik 2-Thio-substituierte Imidazolderivate und ihre Verwendung in der Pharmazie

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3636003A (en) * 1969-11-17 1972-01-18 Geigy Chem Corp Substituted 2-mercaptoimidazole derivatives
DE2856909A1 (de) * 1978-12-28 1980-07-17 Schering Ag Neue imidazolderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
DE3042466A1 (de) * 1980-11-11 1982-06-16 A. Nattermann & Cie GmbH, 5000 Köln N-substituierte (omega) -(2-oxo-4-imidazolin-l-yl)-alkansaeure-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
DE3228271A1 (de) * 1982-07-29 1984-02-02 A. Nattermann & Cie GmbH, 5000 Köln Triphenylimidazolyloxyalkansaeuren und ihre derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate

Also Published As

Publication number Publication date
DE3323870A1 (de) 1985-01-03
JPS6045563A (ja) 1985-03-12
DE3468021D1 (en) 1988-01-21
ZA844835B (en) 1985-02-27
GR82111B (da) 1984-12-13
EP0130526B1 (en) 1987-12-09
EP0130526A1 (en) 1985-01-09
DK319484D0 (da) 1984-06-29
JPH0439462B2 (da) 1992-06-29
DK162439C (da) 1992-03-23
IE841668L (en) 1985-01-02
ATE31300T1 (de) 1987-12-15
DK162439B (da) 1991-10-28
US4654358A (en) 1987-03-31
IE57729B1 (en) 1993-03-24

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