DK3213056T3 - Fremgangsmåder til hurtig forberedelse af mærkede glycosylaminer og til analyse af glykosylerede biomolekyler, som giver samme baggrund - Google Patents
Fremgangsmåder til hurtig forberedelse af mærkede glycosylaminer og til analyse af glykosylerede biomolekyler, som giver samme baggrund Download PDFInfo
- Publication number
- DK3213056T3 DK3213056T3 DK15855907.0T DK15855907T DK3213056T3 DK 3213056 T3 DK3213056 T3 DK 3213056T3 DK 15855907 T DK15855907 T DK 15855907T DK 3213056 T3 DK3213056 T3 DK 3213056T3
- Authority
- DK
- Denmark
- Prior art keywords
- glycosyled
- biomolecules
- procedures
- analysis
- same background
- Prior art date
Links
- 229930182474 N-glycoside Natural products 0.000 title 1
- 150000002341 glycosylamines Chemical class 0.000 title 1
- 238000000034 method Methods 0.000 title 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/924—Hydrolases (3) acting on glycosyl compounds (3.2)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/978—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
- G01N2333/98—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2440/00—Post-translational modifications [PTMs] in chemical analysis of biological material
- G01N2440/38—Post-translational modifications [PTMs] in chemical analysis of biological material addition of carbohydrates, e.g. glycosylation, glycation
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Biophysics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462072747P | 2014-10-30 | 2014-10-30 | |
| US201562107994P | 2015-01-26 | 2015-01-26 | |
| PCT/US2015/057848 WO2016069764A1 (en) | 2014-10-30 | 2015-10-28 | Methods for the rapid preparation of labeled glycosylamines and for the analysis of glycosylated biomolecules producing the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3213056T3 true DK3213056T3 (da) | 2020-09-28 |
Family
ID=55858312
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK20188814.6T DK3748340T3 (da) | 2014-10-30 | 2015-10-28 | Fremgangsmåder til hurtig præparering af mærkede glykosylaminer og til analyse af glykosylerede biomolekyler, som fremstiller samme |
| DK15855907.0T DK3213056T3 (da) | 2014-10-30 | 2015-10-28 | Fremgangsmåder til hurtig forberedelse af mærkede glycosylaminer og til analyse af glykosylerede biomolekyler, som giver samme baggrund |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK20188814.6T DK3748340T3 (da) | 2014-10-30 | 2015-10-28 | Fremgangsmåder til hurtig præparering af mærkede glykosylaminer og til analyse af glykosylerede biomolekyler, som fremstiller samme |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US11371996B2 (da) |
| EP (3) | EP3213056B1 (da) |
| JP (3) | JP7055634B2 (da) |
| CN (2) | CN115753702A (da) |
| DK (2) | DK3748340T3 (da) |
| WO (1) | WO2016069764A1 (da) |
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| US10436790B2 (en) | 2011-09-28 | 2019-10-08 | Waters Technologies Corporation | Rapid fluorescence tagging of glycans and other biomolecules with enhanced MS signals |
| EP3974412A1 (en) | 2011-09-28 | 2022-03-30 | Waters Technologies Corporation | Rapid fluorescence tagging of glycans and other biomolecules with enhanced ms signals |
| US11352325B2 (en) | 2011-09-28 | 2022-06-07 | Waters Technologies Corporation | Rapid fluorescence tagging of glycans and other biomolecules with enhanced MS signals |
| CN115753702A (zh) * | 2014-10-30 | 2023-03-07 | 沃特世科技公司 | 快速制备标记的葡糖基胺和分析生产所述标记的葡糖基胺的糖基化生物分子的方法 |
| US10502720B2 (en) | 2014-11-13 | 2019-12-10 | Waters Technologies Corporation | Methods for liquid chromatography calibration for rapid labeled N-glycans |
| US11061023B2 (en) | 2016-06-21 | 2021-07-13 | Waters Technologies Corporation | Fluorescence tagging of glycans and other biomolecules through reductive amination for enhanced MS signals |
| WO2017222975A1 (en) * | 2016-06-21 | 2017-12-28 | Waters Technologies Corporation | Methods of enhancing ms detection of tagged glycans |
| WO2017222955A1 (en) | 2016-06-21 | 2017-12-28 | Waters Technologies Corporation | Methods of electrospray ionization of glycans modified with amphipathic, strongly basic moieties |
| EP3479103B1 (en) | 2016-07-01 | 2022-04-20 | Waters Technologies Corporation | Methods for the rapid preparation of labeled glycosylamines from complex matrices using molecular weight cut off filtration and on-filter deglycosylation |
| US11280766B2 (en) | 2016-07-28 | 2022-03-22 | Waters Technologies Corporation | Encapsulated pre-analytic workflows for flow-through devices, liquid chromatography and mass spectrometric analysis |
| EP3519832B1 (en) * | 2016-10-03 | 2024-04-03 | Waters Technologies Corporation | Labeled glycan amino acid complexes useful in lc-ms analysis and methods of making the same |
| ES2999550T3 (en) * | 2017-03-31 | 2025-02-26 | Alexion Pharma Inc | Method for simultaneous quantification of alxn1210 and eculizumab in human serum or urine |
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| BR112022013481A2 (pt) | 2020-01-08 | 2022-09-13 | Regeneron Pharma | Uso de aminoácidos para aumentar o sinal em análises espectro de massa |
| CN115398236B (zh) * | 2020-01-21 | 2024-06-11 | 瑞泽恩制药公司 | 用于糖基化的蛋白质的电泳的去糖基化方法 |
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2015
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- 2015-10-28 WO PCT/US2015/057848 patent/WO2016069764A1/en not_active Ceased
- 2015-10-28 DK DK20188814.6T patent/DK3748340T3/da active
- 2015-10-28 JP JP2017523362A patent/JP7055634B2/ja active Active
- 2015-10-28 EP EP15855907.0A patent/EP3213056B1/en active Active
- 2015-10-28 EP EP22160505.8A patent/EP4033223B1/en active Active
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2021
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2023
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| EP4033223B1 (en) | 2025-06-18 |
| EP3748340A1 (en) | 2020-12-09 |
| EP3213056A1 (en) | 2017-09-06 |
| US12158472B2 (en) | 2024-12-03 |
| JP2021119345A (ja) | 2021-08-12 |
| EP3213056B1 (en) | 2020-08-12 |
| US11371996B2 (en) | 2022-06-28 |
| JP2023162207A (ja) | 2023-11-08 |
| JP7687847B2 (ja) | 2025-06-03 |
| US20180188259A1 (en) | 2018-07-05 |
| CN107110785A (zh) | 2017-08-29 |
| JP2018501465A (ja) | 2018-01-18 |
| EP4033223A1 (en) | 2022-07-27 |
| EP3213056A4 (en) | 2018-08-08 |
| EP3748340B1 (en) | 2022-04-06 |
| JP7055634B2 (ja) | 2022-04-18 |
| US20220268779A1 (en) | 2022-08-25 |
| JP7716450B2 (ja) | 2025-07-31 |
| CN115753702A (zh) | 2023-03-07 |
| WO2016069764A1 (en) | 2016-05-06 |
| DK3748340T3 (da) | 2022-04-19 |
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