DK322189A - Imidazo(1,2-a)-(pyridaziner eller pyraziner) til behandling af sygdomme med relation til knogletab - Google Patents

Imidazo(1,2-a)-(pyridaziner eller pyraziner) til behandling af sygdomme med relation til knogletab Download PDF

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Publication number
DK322189A
DK322189A DK322189A DK322189A DK322189A DK 322189 A DK322189 A DK 322189A DK 322189 A DK322189 A DK 322189A DK 322189 A DK322189 A DK 322189A DK 322189 A DK322189 A DK 322189A
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Prior art keywords
pyridazines
pyrazines
imidazo
diseases
relationship
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DK322189A
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English (en)
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DK322189D0 (da
Inventor
Ingemar Starke
Bjoern Wallmark
Kalervo Vaeaenaenen
Original Assignee
Haessle Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Haessle Ab filed Critical Haessle Ab
Publication of DK322189A publication Critical patent/DK322189A/da
Publication of DK322189D0 publication Critical patent/DK322189D0/da

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
    • A61P5/12—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH for decreasing, blocking or antagonising the activity of the posterior pituitary hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK322189A 1987-10-30 1989-06-28 Imidazo(1,2-a)-(pyridaziner eller pyraziner) til behandling af sygdomme med relation til knogletab DK322189D0 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE8704248A SE8704248D0 (sv) 1987-10-30 1987-10-30 Medical use
PCT/SE1988/000576 WO1989003833A1 (en) 1987-10-30 1988-10-27 IMIDAZO(1,2-a)(PYRIDAZINES OR PYRAZINES) FOR TREATMENT OF DISEASES RELATED TO BONE LOSS

Publications (2)

Publication Number Publication Date
DK322189A true DK322189A (da) 1989-06-28
DK322189D0 DK322189D0 (da) 1989-06-28

Family

ID=20370069

Family Applications (1)

Application Number Title Priority Date Filing Date
DK322189A DK322189D0 (da) 1987-10-30 1989-06-28 Imidazo(1,2-a)-(pyridaziner eller pyraziner) til behandling af sygdomme med relation til knogletab

Country Status (9)

Country Link
EP (1) EP0339071A1 (da)
JP (1) JPH02501929A (da)
KR (1) KR890701587A (da)
AU (1) AU2620388A (da)
DK (1) DK322189D0 (da)
HU (1) HU203663B (da)
IL (1) IL88205A0 (da)
SE (1) SE8704248D0 (da)
WO (1) WO1989003833A1 (da)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR890701585A (ko) * 1987-07-16 1989-12-21 헤르베르크 슈키·울리히 볼프 새로운 디아졸
US5081253A (en) * 1989-12-21 1992-01-14 American Home Products Corporation Imidazo(4,5-c)pyridines as antiosteoporotic agents
US5464843A (en) * 1992-06-23 1995-11-07 G.D. Searle & Co. Imidazo[1,2-a]pyridinyldiacid compounds for cognitive enhancement and for treatment of cognitive disorders and neutrotoxic injury
AU5348396A (en) * 1995-05-01 1996-11-21 Fujisawa Pharmaceutical Co., Ltd. Imidazo 1,2-a pyridine and imidazo 1,2-a pyridezine derivati ves and their use as bone resorption inhibitors
GB9518552D0 (en) * 1995-09-11 1995-11-08 Fujisawa Pharmaceutical Co New heterocyclic compounds
US7709468B2 (en) 2005-09-02 2010-05-04 Abbott Laboratories Imidazo based heterocycles
CA2822357A1 (en) 2010-12-22 2012-06-28 Abbvie Inc. Hepatitis c inhibitors and uses thereof
DE102012200349A1 (de) 2012-01-11 2013-07-11 Bayer Intellectual Property Gmbh Substituierte annellierte Pyrimidine und Triazine und ihre Verwendung
US8778964B2 (en) 2012-11-05 2014-07-15 Bayer Pharma Aktiengesellschaft Hydroxy-substituted imidazo[1,2-a]-pyridinecarboxamides and their use
US9624214B2 (en) 2012-11-05 2017-04-18 Bayer Pharma Aktiengesellschaft Amino-substituted imidazo[1,2-a]pyridinecarboxamides and their use
US8796305B2 (en) 2012-11-05 2014-08-05 Bayer Pharma Aktiengesellschaft Carboxy-substituted imidazo[1,2-a]pyridinecarboxamides and their use
US9126998B2 (en) 2012-11-05 2015-09-08 Bayer Pharma AG Amino-substituted imidazo[1,2-a]pyridinecarboxamides and their use
US9776997B2 (en) 2013-06-04 2017-10-03 Bayer Pharma Aktiengesellschaft 3-aryl-substituted imidazo[1,2-A]pyridines and their use
AU2014289312A1 (en) 2013-07-10 2016-02-11 Bayer Pharma Aktiengesellschaft Benzyl-1H-pyrazolo(3,4-b)pyridines and use thereof
US9688699B2 (en) 2014-02-19 2017-06-27 Bayer Pharma Aktiengesellschaft 3-(pyrimidine-2-yl)imidazo[1,2-a]pyridines
WO2015140199A1 (de) 2014-03-21 2015-09-24 Bayer Pharma Aktiengesellschaft Cyano-substituierte imidazo[1,2-a]pyridincarboxamide und ihre verwendung
CA2947376A1 (en) * 2014-05-02 2015-11-05 Bayer Pharma Aktiengesellschaft Imidazo[1,2-a]pyridines as stimulators of soluble guanylate cyclase for treating cardiovascular diseases
JP2017514901A (ja) * 2014-05-02 2017-06-08 バイエル・ファルマ・アクティエンゲゼルシャフト ６−クロロ置換イミダゾ［１，２−ａ］ピリジンカルボキサミドおよびその使用
JP2017514898A (ja) * 2014-05-02 2017-06-08 バイエル・ファルマ・アクティエンゲゼルシャフト 心血管疾患の治療のためのｎ−（２−アミノ−５−フルオロ−２−メチルペンチル）−８−［（２，６−ジフルオロベンジル）オキシ］−２−メチルイミダゾ［１，２−ａ］ピリジン−３−カルボキサミドの、並びにジ−及びトリフルオロ誘導体のエナンチオマー
CN107257796A (zh) 2014-12-02 2017-10-17 拜耳医药股份有限公司 取代的吡唑并[1,5‑a]吡啶和咪唑并[1,2‑a]吡嗪及其用途
US10292970B2 (en) 2014-12-02 2019-05-21 Bayer Pharma Aktiengesellschaft Heteroaryl-substituted imidazo[1,2-A]pyridines and their use
CA2975668A1 (en) 2015-02-05 2016-08-11 Bayer Pharma Aktiengesellschaft Substituted imidazo[1,2-a]pyrazine carboxamides and use thereof
CN107567446A (zh) 2015-02-05 2018-01-09 拜耳制药股份公司 取代的吡唑并[1,5‑a]吡啶‑3‑甲酰胺及其用途
WO2018184976A1 (de) 2017-04-05 2018-10-11 Bayer Pharma Aktiengesellschaft Substituierte imidazo[1,2-a]pyridincarboxamide und ihre verwendung

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3269604D1 (en) * 1981-06-26 1986-04-10 Schering Corp Novel imidazo(1,2-a)pyridines and pyrazines, processes for their preparation and pharmaceutical compositions containing them
US4468400A (en) * 1982-12-20 1984-08-28 Schering Corporation Antiulcer tricyclic imidazo [1,2-a]pyridines
DE3446778A1 (de) * 1984-12-21 1986-07-03 Dr. Karl Thomae Gmbh, 7950 Biberach Neue imidazoderivate, ihre herstellung und diese verbindungen enthaltende arzneimittel
US4725601A (en) * 1985-06-04 1988-02-16 Fujisawa Pharmaceutical Co., Ltd. Certain imidazo[1,2-a]pyridines useful in the treatment of ulcers
EP0228006A1 (en) * 1985-12-16 1987-07-08 Fujisawa Pharmaceutical Co., Ltd. Imidazopyridine compounds and processes for preparation thereof

Also Published As

Publication number Publication date
EP0339071A1 (en) 1989-11-02
SE8704248D0 (sv) 1987-10-30
DK322189D0 (da) 1989-06-28
AU2620388A (en) 1989-05-23
KR890701587A (ko) 1989-12-21
JPH02501929A (ja) 1990-06-28
WO1989003833A1 (en) 1989-05-05
HUT51138A (en) 1990-04-28
IL88205A0 (en) 1989-06-30
HU203663B (en) 1991-09-30

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