DK3234145T3 - Fremgangsmåde til kontrollered aktivering eller eliminering af terapeutiske celler - Google Patents

Fremgangsmåde til kontrollered aktivering eller eliminering af terapeutiske celler Download PDF

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Publication number
DK3234145T3
DK3234145T3 DK15823866.7T DK15823866T DK3234145T3 DK 3234145 T3 DK3234145 T3 DK 3234145T3 DK 15823866 T DK15823866 T DK 15823866T DK 3234145 T3 DK3234145 T3 DK 3234145T3
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Prior art keywords
elimination
procedure
therapeutic cells
controlled activation
activation
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DK15823866.7T
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English (en)
Inventor
David M Spencer
Joseph Henri Bayle
Aaron Edward Foster
Kevin M Slawin
Annemarie Moseley
Matthew R Collinson-Pautz
Mylinh Duong
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Bellicum Pharmaceuticals Inc
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
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    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4747—Apoptosis related proteins
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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    • C07K2319/00—Fusion polypeptide
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DK15823866.7T 2014-12-15 2015-12-14 Fremgangsmåde til kontrollered aktivering eller eliminering af terapeutiske celler DK3234145T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462092149P 2014-12-15 2014-12-15
US201562148386P 2015-04-16 2015-04-16
PCT/US2015/065646 WO2016100241A2 (en) 2014-12-15 2015-12-14 Methods for controlled activation or elimination of therapeutic cells

Publications (1)

Publication Number Publication Date
DK3234145T3 true DK3234145T3 (da) 2019-08-19

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DK15823866.7T DK3234145T3 (da) 2014-12-15 2015-12-14 Fremgangsmåde til kontrollered aktivering eller eliminering af terapeutiske celler

Country Status (9)

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US (2) US20160175359A1 (da)
EP (2) EP3234145B1 (da)
JP (2) JP6720176B2 (da)
AU (2) AU2015362753A1 (da)
CA (1) CA2966241A1 (da)
DK (1) DK3234145T3 (da)
ES (1) ES2743232T3 (da)
HK (1) HK1245827B (da)
WO (1) WO2016100241A2 (da)

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