DK32388A - Phospholipid-baeremiddel for vand-uoploeselige aktive bestanddele - Google Patents
Phospholipid-baeremiddel for vand-uoploeselige aktive bestanddeleInfo
- Publication number
- DK32388A DK32388A DK032388A DK32388A DK32388A DK 32388 A DK32388 A DK 32388A DK 032388 A DK032388 A DK 032388A DK 32388 A DK32388 A DK 32388A DK 32388 A DK32388 A DK 32388A
- Authority
- DK
- Denmark
- Prior art keywords
- phospholipid
- triglyceride
- active ingredient
- water
- active ingredients
- Prior art date
Links
- 239000004480 active ingredient Substances 0.000 title abstract 4
- 150000003904 phospholipids Chemical class 0.000 title abstract 2
- 239000003381 stabilizer Substances 0.000 title 1
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 3
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 abstract 3
- NRJAVPSFFCBXDT-HUESYALOSA-N 1,2-distearoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCCCCCCCCCCCC NRJAVPSFFCBXDT-HUESYALOSA-N 0.000 abstract 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 abstract 2
- VMPHSYLJUKZBJJ-UHFFFAOYSA-N trilaurin Chemical compound CCCCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCCCC)COC(=O)CCCCCCCCCCC VMPHSYLJUKZBJJ-UHFFFAOYSA-N 0.000 abstract 2
- DUXYWXYOBMKGIN-UHFFFAOYSA-N trimyristin Chemical compound CCCCCCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCC DUXYWXYOBMKGIN-UHFFFAOYSA-N 0.000 abstract 2
- 241001465754 Metazoa Species 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- FVJZSBGHRPJMMA-IOLBBIBUSA-N PG(18:0/18:0) Chemical compound CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(=O)OC[C@@H](O)CO)OC(=O)CCCCCCCCCCCCCCCCC FVJZSBGHRPJMMA-IOLBBIBUSA-N 0.000 abstract 1
- 101001000212 Rattus norvegicus Decorin Proteins 0.000 abstract 1
- 238000005054 agglomeration Methods 0.000 abstract 1
- 230000002776 aggregation Effects 0.000 abstract 1
- 229960000473 altretamine Drugs 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 235000012000 cholesterol Nutrition 0.000 abstract 1
- FVJZSBGHRPJMMA-UHFFFAOYSA-N distearoyl phosphatidylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(COP(O)(=O)OCC(O)CO)OC(=O)CCCCCCCCCCCCCCCCC FVJZSBGHRPJMMA-UHFFFAOYSA-N 0.000 abstract 1
- UUVWYPNAQBNQJQ-UHFFFAOYSA-N hexamethylmelamine Chemical compound CN(C)C1=NC(N(C)C)=NC(N(C)C)=N1 UUVWYPNAQBNQJQ-UHFFFAOYSA-N 0.000 abstract 1
- 229940113164 trimyristin Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
- Y10T428/2984—Microcapsule with fluid core [includes liposome]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Dispersion Chemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US733887A | 1987-01-27 | 1987-01-27 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK32388D0 DK32388D0 (da) | 1988-01-25 |
| DK32388A true DK32388A (da) | 1988-07-28 |
Family
ID=21725588
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK032388A DK32388A (da) | 1987-01-27 | 1988-01-25 | Phospholipid-baeremiddel for vand-uoploeselige aktive bestanddele |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US4963363A (de) |
| EP (1) | EP0280394B1 (de) |
| JP (1) | JP2677576B2 (de) |
| KR (1) | KR960009181B1 (de) |
| AT (1) | ATE115403T1 (de) |
| AU (1) | AU604288B2 (de) |
| CA (1) | CA1314213C (de) |
| DE (1) | DE3852409T2 (de) |
| DK (1) | DK32388A (de) |
| ES (1) | ES2068197T3 (de) |
| GR (1) | GR3015290T3 (de) |
| IE (1) | IE65987B1 (de) |
| NO (1) | NO177774C (de) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH03128321A (ja) * | 1989-06-12 | 1991-05-31 | Res Inst For Prod Dev | 人工酸素運搬体 |
| IE904098A1 (en) * | 1989-11-13 | 1991-05-22 | Nova Pharm Corp | Lipospheres for controlled delivery of substances |
| US5188837A (en) * | 1989-11-13 | 1993-02-23 | Nova Pharmaceutical Corporation | Lipsopheres for controlled delivery of substances |
| US5221535A (en) * | 1989-11-13 | 1993-06-22 | Nova Pharmaceutical Corporation | Sustained release formulations of insect repellent |
| SE9003100D0 (sv) * | 1990-09-28 | 1990-09-28 | Kabivitrum Ab | Lipid formulation system |
| US5665379A (en) * | 1990-09-28 | 1997-09-09 | Pharmacia & Upjohn Aktiebolag | Lipid particle forming matrix, preparation and use thereof |
| SE9200951D0 (sv) * | 1992-03-27 | 1992-03-27 | Kabi Pharmacia Ab | Pharmaceutical composition containing a defined lipid system |
| BR9201168A (pt) * | 1992-04-02 | 1994-04-12 | Zerbini E J Fundacao | Microemulsoes usadas como velculo para carregar quimioterapicos as celulas neoplasicas |
| US5885486A (en) * | 1993-03-05 | 1999-03-23 | Pharmaciaand Upjohn Ab | Solid lipid particles, particles of bioactive agents and methods for the manufacture and use thereof |
| US5785976A (en) * | 1993-03-05 | 1998-07-28 | Pharmacia & Upjohn Ab | Solid lipid particles, particles of bioactive agents and methods for the manufacture and use thereof |
| US5714163A (en) * | 1994-06-27 | 1998-02-03 | Nexstar Pharmaceuticals, Inc. | Vinca alkaloid vesicles with enhanced efficacy and tumor targeting properties |
| US6120800A (en) * | 1997-09-25 | 2000-09-19 | Nexstar Pharmaceuticals, Inc. | Vinca-alkaloid vesicles with enhanced efficacy and tumor targeting properties |
| TWI241915B (en) | 1998-05-11 | 2005-10-21 | Ciba Sc Holding Ag | A method of preparing a pharmaceutical end formulation using a nanodispersion |
| EP1441683A4 (de) * | 2001-10-12 | 2005-10-26 | Univ New York | Trisubstituierte triazin-verbindungen und verfahren zur herstellung und verwendung der verbindungen mit antitubulin-wirkung |
| US7592451B2 (en) * | 2005-06-23 | 2009-09-22 | New York University | Treatment for diabetes and obesity as well as method of screening compounds useful for such treatments |
| JP6661319B2 (ja) * | 2015-09-28 | 2020-03-11 | 小林製薬株式会社 | リポソーム |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3957971A (en) * | 1974-07-29 | 1976-05-18 | Lever Brothers Company | Moisturizing units and moisturizing compositions containing the same |
| US4235871A (en) * | 1978-02-24 | 1980-11-25 | Papahadjopoulos Demetrios P | Method of encapsulating biologically active materials in lipid vesicles |
| CA1119955A (en) * | 1978-04-14 | 1982-03-16 | Little (Arthur D.), Inc. | Xenobiotic delivery vehicles, method of forming them and method of using them |
| JPS55153713A (en) * | 1979-05-02 | 1980-11-29 | Kureha Chem Ind Co Ltd | Pharmaceutical preparation of ribosome containing active substance |
| US4534899A (en) * | 1981-07-20 | 1985-08-13 | Lipid Specialties, Inc. | Synthetic phospholipid compounds |
| FR2521565B1 (fr) * | 1982-02-17 | 1985-07-05 | Dior Sa Parfums Christian | Melange pulverulent de constituants lipidiques et de constituants hydrophobes, procede pour le preparer, phases lamellaires lipidiques hydratees et procede de fabrication, compositions pharmaceutiques ou cosmetiques comportant des phases lamellaires lipidiques hydratees |
| FR2534487B1 (fr) * | 1982-10-15 | 1988-06-10 | Dior Christian Parfums | Procede d'homogeneisation de dispersions de phases lamellaires lipidiques hydratees, et suspensions obtenues par ce procede |
| US4515736A (en) * | 1983-05-12 | 1985-05-07 | The Regents Of The University Of California | Method for encapsulating materials into liposomes |
| US4725442A (en) * | 1983-06-17 | 1988-02-16 | Haynes Duncan H | Microdroplets of water-insoluble drugs and injectable formulations containing same |
| US4708861A (en) * | 1984-02-15 | 1987-11-24 | The Liposome Company, Inc. | Liposome-gel compositions |
| US4610868A (en) * | 1984-03-20 | 1986-09-09 | The Liposome Company, Inc. | Lipid matrix carriers for use in drug delivery systems |
| DE3421468A1 (de) * | 1984-06-08 | 1985-12-19 | Dr. Rentschler Arzneimittel Gmbh & Co, 7958 Laupheim | Lipidnanopellets als traegersystem fuer arzneimittel zur peroralen anwendung |
| JPS6348214A (ja) * | 1986-08-18 | 1988-02-29 | Morishita Seiyaku Kk | 1−〔2−(2,4−ジクロロフエニル)−3−メチル−1−ペンテニル〕−1h−イミダゾ−ルを含有する水中油型脂肪乳剤 |
-
1988
- 1988-01-22 DE DE3852409T patent/DE3852409T2/de not_active Expired - Fee Related
- 1988-01-22 EP EP88300529A patent/EP0280394B1/de not_active Expired - Lifetime
- 1988-01-22 AT AT88300529T patent/ATE115403T1/de not_active IP Right Cessation
- 1988-01-22 NO NO880272A patent/NO177774C/no unknown
- 1988-01-22 ES ES88300529T patent/ES2068197T3/es not_active Expired - Lifetime
- 1988-01-22 AU AU10736/88A patent/AU604288B2/en not_active Ceased
- 1988-01-25 IE IE17988A patent/IE65987B1/en not_active IP Right Cessation
- 1988-01-25 KR KR1019880000544A patent/KR960009181B1/ko not_active Expired - Fee Related
- 1988-01-25 CA CA000557283A patent/CA1314213C/en not_active Expired - Fee Related
- 1988-01-25 DK DK032388A patent/DK32388A/da not_active Application Discontinuation
- 1988-01-26 JP JP63015692A patent/JP2677576B2/ja not_active Expired - Lifetime
-
1989
- 1989-05-01 US US07/346,265 patent/US4963363A/en not_active Expired - Lifetime
-
1995
- 1995-03-03 GR GR950400468T patent/GR3015290T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2677576B2 (ja) | 1997-11-17 |
| CA1314213C (en) | 1993-03-09 |
| EP0280394B1 (de) | 1994-12-14 |
| IE65987B1 (en) | 1995-11-29 |
| KR880008802A (ko) | 1988-09-13 |
| NO177774B (no) | 1995-08-14 |
| ES2068197T3 (es) | 1995-04-16 |
| NO880272L (no) | 1988-07-27 |
| JPS63246320A (ja) | 1988-10-13 |
| AU604288B2 (en) | 1990-12-13 |
| NO177774C (no) | 1995-11-22 |
| KR960009181B1 (ko) | 1996-07-16 |
| EP0280394A1 (de) | 1988-08-31 |
| DE3852409T2 (de) | 1995-04-20 |
| ATE115403T1 (de) | 1994-12-15 |
| IE880179L (en) | 1988-07-27 |
| DE3852409D1 (de) | 1995-01-26 |
| DK32388D0 (da) | 1988-01-25 |
| AU1073688A (en) | 1988-07-28 |
| GR3015290T3 (en) | 1995-06-30 |
| NO880272D0 (no) | 1988-01-22 |
| US4963363A (en) | 1990-10-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK32388D0 (da) | Phospholipid-baeremiddel for vand-uoploeselige aktive bestanddele | |
| HUT50794A (en) | Herbicides comprising substituted benztriazole derivatives as active ingredient and process for producing the active ingredients | |
| EP0219922A3 (en) | Anthracycline antineoplastic agents encapsulated in phospholipid micellular particles | |
| IE940583L (en) | Topical antimicrobial pharmaceutical compositions | |
| HUT41221A (en) | Insecticide and acaricide compositions further process for preparing phenoxy-alkyl-amino-pyridine derivatives as active ingredients thereof | |
| CA2281473A1 (en) | Dosage form exhibiting rapid disperse properties, methods of use and process for the manufacture of same | |
| HUT45844A (en) | Pesticides comprising imidazole derivatives as active ingredient and process for producing the active ingredients | |
| HUT45850A (en) | Insecticides comprising azolinone derivatives as active ingredient and process for producing the active ingredients | |
| HUT47383A (en) | Fungicides and insecticides comprising 2-anilino-pyrimidine derivatives as active ingredient and process for producing the active ingredients | |
| HUT41957A (en) | Insecticide compositions containing aryl-pyridon derivatives as active agents and process for producing the active agents | |
| HUT41365A (en) | Insecticide compositions containing substituted benzyl-ether derivatives as active ingredients and process for preparing the active substances | |
| HUT49875A (en) | Herbicides comprising substituted sulfonylaminoazole derivatives as active ingredient and process for producing the active ingredients | |
| HUT41213A (en) | Pesticide compositions containing benzodioxole derivatives as active ingredients and process for preparing the active compounds | |
| HUT41605A (en) | Insecticide compositions containing piridazinone derivatives as active ingredients and process for preparing the active substances | |
| HUT39568A (en) | Insecticide and acaricide compositions containing 13beta-alkyl-milbemycin derivatives as active ingredients further process for preparing the active substances | |
| HUT48217A (en) | Pesticides comprising 5-methylamino-1-arylpyrazole derivatives as active ingredient and process for producing the active ingredients | |
| HUT39569A (en) | Pesticide compositions containing 13beta-milbemycin derivatives and process for preparing the active ingredients | |
| HUT39957A (en) | Insecticide and acaricide compositions and process for preparing the active ingredients | |
| HUT49596A (en) | Herbicides comprising iminophenylthiazolidine derivatives as actie ingredient and process for producing the active ingredients | |
| HUT46508A (en) | Insecticidal compositions comprising 6-member heterocyclic derivatives of n'-substituted-n,n'-diacylhydrazine and process for producing the active ingredients | |
| HUT41230A (en) | Pesticide compositions containing substituted 4,5-dihydro-1,3,4-thiadiazol derivatives as active agents and process for producing the active agents | |
| HUT41376A (en) | Insecticide compositions containing phenyl-hidrazine derivatives as active agents and process for producing the active agents | |
| HUT41211A (en) | Insecticide compositions containing alkane derivatives as active substances and process for preparing the active ingredients | |
| IT1229223B (it) | Composizioni veterinarie sinergisticamente attive e procedimento per la loro preparazione. | |
| HUT40556A (en) | Insecticide composition containing oxim-ether derivatives as active agents and process for producing the active agents |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHB | Application shelved due to non-payment |