DK324484A - Hidtil ukendte benzofuranderivater, deres fremstilling og deres terapeutiske anvendelse - Google Patents

Hidtil ukendte benzofuranderivater, deres fremstilling og deres terapeutiske anvendelse Download PDF

Info

Publication number: DK324484A
Authority: DK; Denmark
Prior art keywords: derivatives; benzofurand; unknown; preparation; therapeutic use
Prior art date: 1983-07-18

Application number

DK324484A

Other languages

English (en)

Other versions

DK164861C (da

DK324484D0 (da

DK164861B (da

Inventor

Marcel Descamps

Peter Polster

Original Assignee

Sanofi Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-07-18

Filing date

1984-07-02

Publication date

1985-01-19

1984-07-02 Application filed by Sanofi Sa filed Critical Sanofi Sa

1984-07-02 Publication of DK324484D0 publication Critical patent/DK324484D0/da

1985-01-19 Publication of DK324484A publication Critical patent/DK324484A/da

1992-08-31 Publication of DK164861B publication Critical patent/DK164861B/da

1993-01-18 Application granted granted Critical

1993-01-18 Publication of DK164861C publication Critical patent/DK164861C/da

Links

230000001225 therapeutic effect Effects 0.000 title 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical group [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 abstract 1
ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical group [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
-1 alkyl radical Chemical class 0.000 abstract 1
230000001466 anti-adreneric effect Effects 0.000 abstract 1
GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Chemical group BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
229910052794 bromium Chemical group 0.000 abstract 1
239000011575 calcium Substances 0.000 abstract 1
229910052791 calcium Inorganic materials 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
210000000748 cardiovascular system Anatomy 0.000 abstract 1
239000000460 chlorine Chemical group 0.000 abstract 1
229910052801 chlorine Inorganic materials 0.000 abstract 1
150000001907 coumarones Chemical class 0.000 abstract 1
125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
230000002401 inhibitory effect Effects 0.000 abstract 1
125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 abstract 1
125000004108 n-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 abstract 1
125000004123 n-propyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])* 0.000 abstract 1
230000001575 pathological effect Effects 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
208000011580 syndromic disease Diseases 0.000 abstract 1
230000005945 translocation Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/80—Radicals substituted by oxygen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Obesity (AREA)
Hematology (AREA)
Diabetes (AREA)
Rheumatology (AREA)
Endocrinology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Furan Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Compositions Of Macromolecular Compounds (AREA)

DK324484A 1983-07-18 1984-07-02 Hidtil ukendte benzofuranderivater, en fremgangsmaade til deres fremstilling og farmaceutiske eller veterinaere midler indeholdende et saadant derivat DK164861C (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR8311805		1983-07-18
FR8311805A FR2549475B1 (fr)	1983-07-18	1983-07-18	Nouveaux derives de benzofuranne, leur preparation et leur utilisation therapeutique

Publications (4)

Publication Number	Publication Date
DK324484D0 DK324484D0 (da)	1984-07-02
DK324484A true DK324484A (da)	1985-01-19
DK164861B DK164861B (da)	1992-08-31
DK164861C DK164861C (da)	1993-01-18

Family

ID=9290860

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK324484A DK164861C (da)	1983-07-18	1984-07-02	Hidtil ukendte benzofuranderivater, en fremgangsmaade til deres fremstilling og farmaceutiske eller veterinaere midler indeholdende et saadant derivat

Country Status (18)

Country	Link
US (1)	US4565828A (da)
EP (1)	EP0135489B1 (da)
JP (1)	JPS6038377A (da)
KR (1)	KR870001795B1 (da)
AT (1)	ATE30588T1 (da)
AU (1)	AU560626B2 (da)
BE (1)	BE900139A (da)
CA (1)	CA1214782A (da)
DE (1)	DE3467169D1 (da)
DK (1)	DK164861C (da)
ES (1)	ES8504163A1 (da)
FR (1)	FR2549475B1 (da)
GR (1)	GR79959B (da)
IE (1)	IE57842B1 (da)
IL (1)	IL72292A (da)
NZ (1)	NZ208922A (da)
PT (1)	PT78918B (da)
ZA (1)	ZA845471B (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5274000A (en) *	1982-10-19	1993-12-28	Kotobuki Seiyaku Company Limited	Benzofuran and benzothiophene derivatives, anti-hyperuricemia agents
US5175184A (en) *	1982-10-19	1992-12-29	Kotobuki Seiyaku Company Limited	Benzothiophene derivatives and antihyperuricemia thereof
FR2550091B1 (fr) *	1983-08-02	1986-05-23	Sanofi Sa	Composition pharmaceutique ou veterinaire destinee a combattre des troubles ischemiques cardiaques contenant un derive du benzofuranne
FR2565979B1 (fr) *	1984-06-13	1987-03-20	Labaz Sanofi Nv	Nouveaux derives de decahydroquinoleinol, leur procede de preparation et les compositions les contenant
US4831054A (en) *	1988-04-18	1989-05-16	Taro Pharmaceuticals, Ltd.	2-Alkyl-3-benzoylbenzofurans useful for treating cardiac arrhythmia
CA2112890A1 (en) *	1991-07-09	1993-01-21	Shoichi Chokai	Benzofuran derivative and pharmaceutical composition

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3248401A (en) *		1966-04-26		Diethylaminoe hoxybenzoyl benzofurans
GB1299247A (en) *	1970-06-22	1972-12-13	Labaz	Benzofuran derivatives and process for preparing the same
GB1382742A (en) *	1972-09-19	1975-02-05	Labaz	Benzofuran derivatives and process for preparing the same

1983
- 1983-07-18 FR FR8311805A patent/FR2549475B1/fr not_active Expired
1984
- 1984-07-02 DK DK324484A patent/DK164861C/da not_active IP Right Cessation
- 1984-07-03 IL IL72292A patent/IL72292A/xx not_active IP Right Cessation
- 1984-07-05 AU AU30302/84A patent/AU560626B2/en not_active Ceased
- 1984-07-05 US US06/628,208 patent/US4565828A/en not_active Expired - Lifetime
- 1984-07-12 BE BE0/213318A patent/BE900139A/fr not_active IP Right Cessation
- 1984-07-12 EP EP84870102A patent/EP0135489B1/fr not_active Expired
- 1984-07-12 AT AT84870102T patent/ATE30588T1/de not_active IP Right Cessation
- 1984-07-12 DE DE8484870102T patent/DE3467169D1/de not_active Expired
- 1984-07-16 KR KR1019840004186A patent/KR870001795B1/ko not_active Expired
- 1984-07-16 GR GR75321A patent/GR79959B/el unknown
- 1984-07-16 CA CA000458977A patent/CA1214782A/en not_active Expired
- 1984-07-16 PT PT78918A patent/PT78918B/pt not_active IP Right Cessation
- 1984-07-16 IE IE1825/84A patent/IE57842B1/en not_active IP Right Cessation
- 1984-07-16 ZA ZA845471A patent/ZA845471B/xx unknown
- 1984-07-17 NZ NZ208922A patent/NZ208922A/en unknown
- 1984-07-18 JP JP59149277A patent/JPS6038377A/ja active Granted
- 1984-07-18 ES ES534400A patent/ES8504163A1/es not_active Expired

Also Published As

Publication number	Publication date
FR2549475B1 (fr)	1986-02-07
DK164861C (da)	1993-01-18
DE3467169D1 (en)	1987-12-10
DK324484D0 (da)	1984-07-02
NZ208922A (en)	1987-01-23
AU560626B2 (en)	1987-04-09
JPH0587514B2 (da)	1993-12-16
KR870001795B1 (ko)	1987-10-12
IE57842B1 (en)	1993-04-21
EP0135489B1 (fr)	1987-11-04
KR850001188A (ko)	1985-03-16
EP0135489A1 (fr)	1985-03-27
ES534400A0 (es)	1985-04-01
ES8504163A1 (es)	1985-04-01
AU3030284A (en)	1985-01-24
GR79959B (da)	1984-10-31
BE900139A (fr)	1985-01-14
IE841825L (en)	1985-01-18
ZA845471B (en)	1985-02-27
CA1214782A (en)	1986-12-02
IL72292A (en)	1987-10-20
US4565828A (en)	1986-01-21
IL72292A0 (en)	1984-11-30
ATE30588T1 (de)	1987-11-15
JPS6038377A (ja)	1985-02-27
FR2549475A1 (fr)	1985-01-25
PT78918A (en)	1984-08-01
DK164861B (da)	1992-08-31
PT78918B (en)	1986-06-02

Legal Events

Date	Code	Title	Description
1996-03-25	PBP	Patent lapsed

Publication	Publication Date	Title
AU560626B2 (en)	1987-04-09	2-alkyl-3-substituted phenylcarbonyl-benzofurans
AU553758B2 (en)	1986-07-24	Indolizine derivatives
DK12584A (da)	1984-07-15	Bicyclo(4.2.0)1,3,5-octatrienderivater, fremgangsmaade til deres fremstilling og farmaceutiske kompositioner indeholdende disse
DK228086D0 (da)	1986-05-16	Substituerede isoxazol-derivater med antiviral virkning og fremgangsmaade af saadanne derivater
AU551901B2 (en)	1986-05-15	Substituted thienobenzodiazepinones
SE7605899L (sv)	1976-11-29	Forfarande for framstellning av tienopyridinderivat
DE3464602D1 (en)	1987-08-13	4-alkylimidazole derivatives, their preparation and their application
ZA8312B (en)	1983-09-28	Substituted 1-benzoyl-2-phenyliminiomidazolidine derivatives
SE7706693L (sv)	1977-12-12	Sett att framstella hydrazinopyridazinderivat
AU575758B2 (en)	1988-08-04	Decahydroquinolinol derivatives