DK3294911T3 - Platform til opdagelse og analyse af terapeutiske midler - Google Patents

Platform til opdagelse og analyse af terapeutiske midler Download PDF

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Publication number
DK3294911T3
DK3294911T3 DK16793337.3T DK16793337T DK3294911T3 DK 3294911 T3 DK3294911 T3 DK 3294911T3 DK 16793337 T DK16793337 T DK 16793337T DK 3294911 T3 DK3294911 T3 DK 3294911T3
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discovery
platform
analysis
therapeutic agents
therapeutic
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DK16793337.3T
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English (en)
Inventor
Molly He
Michael Previte
Misha Golynskiy
Matthew William Kellinger
Sergio Peisajovich
Jonathan Mark Boutell
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Illumina Inc
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    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B50/00—Methods of creating libraries, e.g. combinatorial synthesis
    • C40B50/14—Solid phase synthesis, i.e. wherein one or more library building blocks are bound to a solid support during library creation; Particular methods of cleavage from the solid support
    • C40B50/16—Solid phase synthesis, i.e. wherein one or more library building blocks are bound to a solid support during library creation; Particular methods of cleavage from the solid support involving encoding steps
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
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    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B20/00—Methods specially adapted for identifying library members
    • C40B20/04—Identifying library members by means of a tag, label, or other readable or detectable entity associated with the library members, e.g. decoding processes
    • G—PHYSICS
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G—PHYSICS
    • G01—MEASURING; TESTING
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    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
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    • B01J2219/00277—Apparatus
    • B01J2219/00279—Features relating to reactor vessels
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    • B01J2219/00313—Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks
    • B01J2219/00315—Microtiter plates
    • B01J2219/00317—Microwell devices, i.e. having large numbers of wells
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    • C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
    • C12Q2563/131—Nucleic acid detection characterized by the use of physical, structural and functional properties the label being a member of a cognate binding pair, i.e. extends to antibodies, haptens, avidin
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    • C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
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    • C12Q2565/00—Nucleic acid analysis characterised by mode or means of detection
    • C12Q2565/50—Detection characterised by immobilisation to a surface
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    • C12Q2565/00—Nucleic acid analysis characterised by mode or means of detection
    • C12Q2565/50—Detection characterised by immobilisation to a surface
    • C12Q2565/515—Detection characterised by immobilisation to a surface characterised by the interaction between or sequential use of two or more arrays

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Clinical Laboratory Science (AREA)
  • Structural Engineering (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Medical Treatment And Welfare Office Work (AREA)
DK16793337.3T 2015-05-11 2016-05-09 Platform til opdagelse og analyse af terapeutiske midler DK3294911T3 (da)

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US201562159710P 2015-05-11 2015-05-11
PCT/US2016/031524 WO2016183029A1 (en) 2015-05-11 2016-05-09 Platform for discovery and analysis of therapeutic agents

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DK16793337.3T DK3294911T3 (da) 2015-05-11 2016-05-09 Platform til opdagelse og analyse af terapeutiske midler
DK20216661.7T DK3822365T3 (da) 2015-05-11 2016-05-09 Platform til opdagelse og analyse af terapeutiske midler

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EP (4) EP3294911B1 (da)
JP (3) JP2018518157A (da)
KR (2) KR102333255B1 (da)
CN (2) CN107810415B (da)
AU (1) AU2016261496B2 (da)
BR (1) BR112017023188B1 (da)
CA (2) CA2983932C (da)
DK (3) DK3760737T3 (da)
ES (3) ES2938072T3 (da)
FI (2) FI3760737T3 (da)
IL (3) IL290908B2 (da)
RU (1) RU2724998C2 (da)
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US11795580B2 (en) 2017-05-02 2023-10-24 Haystack Sciences Corporation Molecules for verifying oligonucleotide directed combinatorial synthesis and methods of making and using the same
CN115506034B (zh) 2017-09-25 2025-12-05 普莱克斯姆公司 寡核苷酸编码的化学文库
CN109444425A (zh) * 2018-11-01 2019-03-08 上海交通大学 一种细胞水平蛋白高通量检测方法
JP7365022B2 (ja) * 2019-10-28 2023-10-19 日本電信電話株式会社 生体分子の支持体とその製造方法
US12577702B2 (en) 2020-01-28 2026-03-17 Plexium, Inc. Oligonucleotide encoded chemical libraries, related systems, devices, and methods for detecting, analyzing, quantifying, and testing biologics/genetics
US20230212555A1 (en) * 2020-02-28 2023-07-06 Synvitrobio, Inc. Methods and compositions for identifying traits using a cell-free system
US20230193245A1 (en) * 2020-06-29 2023-06-22 Google Llc Methods and compositions for making and using peptide arrays
CN115768863A (zh) * 2020-07-06 2023-03-07 索尼集团公司 生物粒子分析方法和生物粒子分析系统
GB202112907D0 (en) 2021-09-10 2021-10-27 Res & Innovation Uk Methods of biomolecule display

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