DK3350201T3 - Manipulerede fytaser og fremgangsmåder til anvendelse af samme - Google Patents

Manipulerede fytaser og fremgangsmåder til anvendelse af samme Download PDF

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Publication number
DK3350201T3
DK3350201T3 DK16847392.4T DK16847392T DK3350201T3 DK 3350201 T3 DK3350201 T3 DK 3350201T3 DK 16847392 T DK16847392 T DK 16847392T DK 3350201 T3 DK3350201 T3 DK 3350201T3
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DK
Denmark
Prior art keywords
phytases
manipulated
methods
same
manipulated phytases
Prior art date
Application number
DK16847392.4T
Other languages
English (en)
Inventor
R Michael Raab
Gabor Lazar
Binzhang Shen
Original Assignee
Agrivida Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agrivida Inc filed Critical Agrivida Inc
Application granted granted Critical
Publication of DK3350201T3 publication Critical patent/DK3350201T3/da

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Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/14—Pretreatment of feeding-stuffs with enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/189—Enzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245—Escherichia (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/38—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from Aspergillus
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/39—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/03—Phosphoric monoester hydrolases (3.1.3)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Polymers & Plastics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Plant Pathology (AREA)
  • Animal Husbandry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cell Biology (AREA)
  • Physiology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK16847392.4T 2015-09-18 2016-09-16 Manipulerede fytaser og fremgangsmåder til anvendelse af samme DK3350201T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562220688P 2015-09-18 2015-09-18
PCT/US2016/052147 WO2017049094A1 (en) 2015-09-18 2016-09-16 Engineered phytases and methods of using the same

Publications (1)

Publication Number Publication Date
DK3350201T3 true DK3350201T3 (da) 2022-03-07

Family

ID=58289629

Family Applications (1)

Application Number Title Priority Date Filing Date
DK16847392.4T DK3350201T3 (da) 2015-09-18 2016-09-16 Manipulerede fytaser og fremgangsmåder til anvendelse af samme

Country Status (9)

Country Link
US (3) US10687542B2 (da)
EP (1) EP3350201B1 (da)
CN (1) CN108026145B (da)
AU (1) AU2016323780B2 (da)
CL (1) CL2018000708A1 (da)
DK (1) DK3350201T3 (da)
HK (1) HK1254830A1 (da)
MX (2) MX381375B (da)
WO (1) WO2017049094A1 (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2015016371A (es) 2013-06-04 2017-02-15 Tribiotica Llc Métodos y composiciones para ensamblaje templado de heterocompuestos específicos de acido nucleico.
JP6910295B2 (ja) 2014-12-02 2021-07-28 トリビオティカ・エルエルシー 診断治療融合的な応用のための方法及びキット
AU2016323780B2 (en) * 2015-09-18 2021-11-11 Agrivida, Inc. Engineered phytases and methods of using the same
EP3541952A4 (en) 2016-11-21 2020-06-24 Tribiotica Llc METHOD FOR PREVENTING THE TITRATION OF BIMOLECULAR TEMPLATE REACTIONS BY STRUCTURALLY DETERMINED DIFFERENTIAL HYBRIDIZATIONS
EP3541940A4 (en) 2016-11-21 2020-10-14 Tribiotica Llc DIRECTED FOLDING ASSEMBLY OR PROTEIN DIMERIZATION PROCESSES BY MATRIX ASSEMBLY REACTIONS
GB201706430D0 (en) * 2017-04-24 2017-06-07 Univ Oxford Innovation Ltd Proteins and peptide tags with enhanced rate of spontaneous isopeptide bond formation and uses thereof
CA3072569A1 (en) * 2017-08-11 2019-02-14 Tribiotica Llc Methods for generating epitopes for binding to recognition molecules by templated assembly
CN112367847A (zh) * 2018-04-26 2021-02-12 丹尼斯科美国公司 增加固体组合物中植酸酶的稳定性的方法及包含磷酸盐和植酸酶的颗粒组合物
CN110872585B (zh) * 2018-08-29 2021-10-19 北京科技大学 用SpyTag/SpyCatcher环化的L-β-羟基-α-氨基酸合成酶及其用途
EP3737751A1 (en) * 2019-03-21 2020-11-18 Fornia BioSolutions, Inc. Additional phytase variants and methods
CN110846336B (zh) * 2019-11-26 2022-12-20 温氏食品集团股份有限公司 一种多功能融合酶xaet和多功能融合酶定点整合真核特异表达载体及其构建方法
EP4119660A1 (en) * 2021-07-16 2023-01-18 AB Enzymes Oy Phytase variants
EP4119661A1 (en) * 2021-07-16 2023-01-18 AB Enzymes Oy Phytase variants with improved stability and ip4 activity
CN113832126A (zh) * 2021-11-27 2021-12-24 中国农业科学院北京畜牧兽医研究所 一种提高植酸酶热稳定性的方法及融合植酸酶
CN114672505A (zh) * 2022-03-15 2022-06-28 江苏省中国科学院植物研究所 一种功能性表达细胞色素p450酶的方法及其应用
CN115093470B (zh) * 2022-06-30 2023-03-24 广州市乾相生物科技有限公司 内含肽Mtu RecA突变体及其在生产谷胱甘肽GSH中的应用
WO2024181806A1 (ko) * 2023-02-28 2024-09-06 건국대학교 산학협력단 단백질 환형화 시스템
WO2025226702A1 (en) 2024-04-22 2025-10-30 Green Plains Inc. Back-end processing of co-products from ethanol plants

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3754936B2 (ja) * 2001-07-10 2006-03-15 キヤノン株式会社 ポリヒドロキシアルカノエート含有構造体およびその製造方法
CN102031272A (zh) 2002-01-08 2011-04-27 迈克尔·R·拉尔布 表达civps或内含肽修饰蛋白的转基因植物及其制备方法
EP1749022A2 (en) 2004-05-24 2007-02-07 Rigel Pharmaceuticals, Inc. Methods for cyclizing synthetic polymers
US7629139B2 (en) 2005-06-21 2009-12-08 Ab Enzymes Gmbh Extraction methods and assays for feed enzymes
WO2008143679A2 (en) 2006-06-01 2008-11-27 Verenium Corporation Nucleic acids and proteins and methods for making and using them
HUE029140T2 (hu) 2006-09-21 2017-02-28 Basf Enzymes Llc Fitázok, ezeket kódoló nukleinsavak, valamint eljárások az elõállításukra és alkalmazásuk
BRPI0820653B1 (pt) * 2007-12-03 2023-05-16 Syngenta Participations Ag Fitase isolada termotolerante e enzimaticamente suscetível, polinucleotídeo, cassete de expressão, vetor, célula hospedeira microbiana, método para preparar a referida fitase, preparação e ração animal
CN101638642B (zh) * 2008-08-01 2012-02-22 中国农业科学院生物技术研究所 提高了热稳定性及蛋白酶抗性的环化植酸酶
DK2491120T3 (da) * 2009-10-22 2016-03-21 Basf Se Syntetiske phytasevarianter
US10407742B2 (en) * 2009-11-06 2019-09-10 Agrivida, Inc. Intein-modified enzymes, their production and industrial applications
US9464333B2 (en) * 2009-11-06 2016-10-11 Agrivida, Inc. Intein-modified enzymes, their production and industrial applications
US8420387B2 (en) * 2009-11-06 2013-04-16 Agrivida, Inc. Intein-modified enzymes, their production and industrial applications
US20120190609A1 (en) * 2010-08-30 2012-07-26 Martin Bader Method for producing a lipid particle, the lipid particle itself and its use
DK2811844T3 (da) * 2012-02-07 2020-06-29 Danisco Us Inc Fremgangsmåde til forbedring af stabilitet af phytase med phytinsyre og sammensætninger, der omfatter phytase og phytinsyre
WO2013127700A1 (en) * 2012-02-29 2013-09-06 F. Hoffmann-La Roche Ag Method for reduction of 1->2 reading frame shifts
AU2016323780B2 (en) * 2015-09-18 2021-11-11 Agrivida, Inc. Engineered phytases and methods of using the same

Also Published As

Publication number Publication date
US11241025B2 (en) 2022-02-08
CN108026145B (zh) 2022-06-10
US20200275679A1 (en) 2020-09-03
CN108026145A (zh) 2018-05-11
US11805792B2 (en) 2023-11-07
EP3350201A4 (en) 2019-05-08
BR112018005287A2 (pt) 2018-12-11
EP3350201B1 (en) 2022-02-16
US20220095647A1 (en) 2022-03-31
MX381375B (es) 2025-03-12
US20180255804A1 (en) 2018-09-13
MX2018003389A (es) 2019-09-18
WO2017049094A1 (en) 2017-03-23
CL2018000708A1 (es) 2018-12-07
CA2996313A1 (en) 2017-03-23
MX2021004102A (es) 2021-06-08
HK1254830A1 (zh) 2019-07-26
AU2016323780B2 (en) 2021-11-11
US10687542B2 (en) 2020-06-23
AU2016323780A1 (en) 2018-03-08
EP3350201A1 (en) 2018-07-25

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