DK3354737T3 - System til cellefri proteinsyntese - Google Patents

System til cellefri proteinsyntese Download PDF

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Publication number
DK3354737T3
DK3354737T3 DK17153005.8T DK17153005T DK3354737T3 DK 3354737 T3 DK3354737 T3 DK 3354737T3 DK 17153005 T DK17153005 T DK 17153005T DK 3354737 T3 DK3354737 T3 DK 3354737T3
Authority
DK
Denmark
Prior art keywords
cell
protein synthesis
free protein
free
synthesis
Prior art date
Application number
DK17153005.8T
Other languages
English (en)
Inventor
Matthias Buntru
Simon Vogel
Stefan Schillberg
Original Assignee
Fraunhofer Ges Forschung
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fraunhofer Ges Forschung filed Critical Fraunhofer Ges Forschung
Application granted granted Critical
Publication of DK3354737T3 publication Critical patent/DK3354737T3/da

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Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N3/00—Preservation of plants or parts thereof, e.g. inhibiting evaporation, improvement of the appearance of leaves or protection against physical influences such as UV radiation using chemical compositions; Grafting wax
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Plant Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dentistry (AREA)
  • Toxicology (AREA)
  • Agronomy & Crop Science (AREA)
  • Environmental Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK17153005.8T 2017-01-25 2017-01-25 System til cellefri proteinsyntese DK3354737T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP17153005.8A EP3354737B1 (en) 2017-01-25 2017-01-25 Cell-free protein synthesis system

Publications (1)

Publication Number Publication Date
DK3354737T3 true DK3354737T3 (da) 2020-11-09

Family

ID=57960247

Family Applications (2)

Application Number Title Priority Date Filing Date
DK17153005.8T DK3354737T3 (da) 2017-01-25 2017-01-25 System til cellefri proteinsyntese
DK18702200.9T DK3574100T3 (da) 2017-01-25 2018-01-25 Cellefrit proteinsyntesesystem

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK18702200.9T DK3574100T3 (da) 2017-01-25 2018-01-25 Cellefrit proteinsyntesesystem

Country Status (8)

Country Link
US (1) US11317623B2 (da)
EP (2) EP3354737B1 (da)
JP (1) JP7030137B2 (da)
CN (1) CN110199027B (da)
AR (1) AR110849A1 (da)
CA (1) CA3049825C (da)
DK (2) DK3354737T3 (da)
WO (1) WO2018138195A1 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB202013063D0 (en) 2020-08-21 2020-10-07 Nuclera Nucleics Ltd Real-time monitoring of in vitro protein synthesis
JP7802062B2 (ja) * 2020-08-21 2026-01-19 ヌークレラ リミテッド インビトロタンパク質合成のモニタリング
US12426594B2 (en) 2020-09-24 2025-09-30 Everest Medical Innovation GmbH Cryoprotective compositions and methods for protection of a surgical site during cryosurgery
US12453805B2 (en) 2020-09-24 2025-10-28 Everest Medical Innovation GmbH Cryoprotective compositions, surgical kits, and methods for protection of a surgical site during cryosurgery
US20240279702A1 (en) * 2021-06-30 2024-08-22 Corteva Agriscience Llc Soybean and maize cell-free expression systems
CN113584014B (zh) * 2021-07-27 2023-01-20 上海兆维科技发展有限公司 一种rna的制备方法、合成蛋白质的方法以及转录反应液
GB202311185D0 (en) * 2023-07-20 2023-09-06 Nuclera Nucleics Ltd Protein expression reagents
KR102873056B1 (ko) * 2023-11-15 2025-10-23 대한민국(방위사업청장) 무세포 단백질 합성 반응액의 안정한 보관을 위한 동결건조 제형 및 이의 제조방법
CN120193045B (zh) * 2025-05-23 2025-09-23 杭州广科安德生物科技有限公司 一种结核分枝杆菌药敏试剂盒及其方法和应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020039771A1 (en) * 1996-07-16 2002-04-04 Lars-Erik Peters Method for producing complex multienzymatical, storage resistant reaction mixtures and use thereof
US6168931B1 (en) 1999-03-17 2001-01-02 The Board Of Trustees Of The Leland Stanford Junior University Enhanced in vitro synthesis of biological macromolecules using a novel ATP regeneration system
US6337191B1 (en) 1999-03-22 2002-01-08 The Board Of Trustees Of The Leland Stanford Junior University Vitro protein synthesis using glycolytic intermediates as an energy source
JP2002125693A (ja) * 2000-10-19 2002-05-08 Toyobo Co Ltd 無細胞タンパク質合成用細胞抽出液組成物
AU2002356749A1 (en) * 2001-11-28 2003-06-10 Hermann Katinger Process for the production of polypeptides in mammalian cell cultures
US20110195845A1 (en) * 2008-06-11 2011-08-11 Dow Agrosciences Llc Constructs for Expressing Herbicide Tolerance Genes, Related Plants, and Related Trait Combinations
JP6012164B2 (ja) * 2011-11-25 2016-10-25 住友化学株式会社 多能性幹細胞由来の組織の凍結保存方法
JP2016521568A (ja) 2013-06-12 2016-07-25 ユニヴェルシテ・ドゥ・ナミュールUniversite de Namur 生細胞の冷凍保存
EP3242931B1 (en) * 2015-01-08 2021-03-31 Sutro Biopharma, Inc. Formulations for stabilizing bacterial cell extracts

Also Published As

Publication number Publication date
CA3049825A1 (en) 2018-08-02
US11317623B2 (en) 2022-05-03
US20190380330A1 (en) 2019-12-19
WO2018138195A1 (en) 2018-08-02
JP7030137B2 (ja) 2022-03-04
EP3354737B1 (en) 2020-08-19
CN110199027B (zh) 2022-11-18
DK3574100T3 (da) 2022-03-28
EP3574100B1 (en) 2021-12-22
JP2020506721A (ja) 2020-03-05
AR110849A1 (es) 2019-05-08
CA3049825C (en) 2023-05-02
CN110199027A (zh) 2019-09-03
EP3574100A1 (en) 2019-12-04
EP3354737A1 (en) 2018-08-01

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