DK3377894T3 - Fremgangsmåde til lægemiddel-bindingsanalyse i en vævsprøve - Google Patents
Fremgangsmåde til lægemiddel-bindingsanalyse i en vævsprøve Download PDFInfo
- Publication number
- DK3377894T3 DK3377894T3 DK16801740.8T DK16801740T DK3377894T3 DK 3377894 T3 DK3377894 T3 DK 3377894T3 DK 16801740 T DK16801740 T DK 16801740T DK 3377894 T3 DK3377894 T3 DK 3377894T3
- Authority
- DK
- Denmark
- Prior art keywords
- procedure
- test sample
- binding analysis
- pharmaceutical binding
- pharmaceutical
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5082—Supracellular entities, e.g. tissue, organisms
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/60—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances involving radioactive labelled substances
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6848—Methods of protein analysis involving mass spectrometry
- G01N33/6851—Methods of protein analysis involving laser desorption ionisation mass spectrometry
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/0004—Imaging particle spectrometry
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2458/00—Labels used in chemical analysis of biological material
- G01N2458/15—Non-radioactive isotope labels, e.g. for detection by mass spectrometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Optics & Photonics (AREA)
- Toxicology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Enzymes And Modification Thereof (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE1551503 | 2015-11-20 | ||
| PCT/EP2016/078131 WO2017085251A1 (en) | 2015-11-20 | 2016-11-18 | Method for drug binding analysis in a tissue sample |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3377894T3 true DK3377894T3 (da) | 2020-03-23 |
Family
ID=57406220
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK16801740.8T DK3377894T3 (da) | 2015-11-20 | 2016-11-18 | Fremgangsmåde til lægemiddel-bindingsanalyse i en vævsprøve |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US10718760B2 (da) |
| EP (1) | EP3377894B1 (da) |
| JP (1) | JP6906515B2 (da) |
| KR (1) | KR20180082588A (da) |
| CN (1) | CN108431601B (da) |
| BR (1) | BR112018010156A8 (da) |
| DK (1) | DK3377894T3 (da) |
| ES (1) | ES2781374T3 (da) |
| IL (1) | IL259328B (da) |
| WO (1) | WO2017085251A1 (da) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102535976B1 (ko) * | 2016-06-13 | 2023-05-23 | 건국대학교 산학협력단 | 형광이미지 및 질량 분석을 이용한 의약품의 생체분포도를 상호보완적으로 확인하는 방법 |
| CN110291089B (zh) | 2017-01-17 | 2022-05-27 | 海帕瑞吉尼克斯股份有限公司 | 用于促进肝再生或者减少或预防肝细胞死亡的蛋白激酶抑制剂 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU7877494A (en) | 1993-10-22 | 1995-05-08 | Ligand Pharmaceuticals Incorporated | Isotopically-labeled retinoids, their production and use |
| US6645733B1 (en) * | 1999-06-25 | 2003-11-11 | Ingeneus Corporation | Fluorescent intensity method for assaying binding between proteins or peptides |
| FR2840407B1 (fr) * | 2002-05-31 | 2008-07-18 | Commissariat Energie Atomique | Methode de criblage de banques de biomolecules et ses applications |
| CA2559809A1 (en) * | 2004-03-12 | 2005-11-10 | Human Genome Sciences, Inc. | Antibodies against human g-protein chemokine receptor (ccr5) hdgnr10 |
| US8263377B2 (en) * | 2007-04-03 | 2012-09-11 | Plexera, Llc | Label free kinase assays and reagents |
| US20090118135A1 (en) * | 2007-06-08 | 2009-05-07 | The Burnham Institute | Methods and compounds for regulating apoptosis |
| JP4954165B2 (ja) * | 2007-09-07 | 2012-06-13 | キヤノン株式会社 | 化合物、診断薬、核磁気共鳴分析方法、核磁気共鳴イメージング方法、質量分析方法及び質量分析イメージング方法 |
| CN102103132B (zh) * | 2009-12-18 | 2013-06-19 | 中国科学院大连化学物理研究所 | 一种从体液代谢组轮廓筛选糖尿病标记物的方法 |
| FR2973112B1 (fr) * | 2011-03-21 | 2018-05-25 | Imabiotech | Procede de detection et de quantification d'une molecule cible dans un echantillon |
| WO2013036885A1 (en) * | 2011-09-08 | 2013-03-14 | The Regents Of The University Of California | Metabolic flux measurement, imaging and microscopy |
| JP6389479B2 (ja) * | 2013-02-25 | 2018-09-12 | イマビオテクImabiotech | 目的の分子の組織ターゲティングを評価するための方法 |
| WO2015038784A1 (en) * | 2013-09-13 | 2015-03-19 | The Board Of Trustees Of The Leland Stanford Junior University | Multiplexed imaging of tissues using mass tags and secondary ion mass spectrometry |
-
2016
- 2016-11-18 DK DK16801740.8T patent/DK3377894T3/da active
- 2016-11-18 CN CN201680067740.4A patent/CN108431601B/zh not_active Expired - Fee Related
- 2016-11-18 JP JP2018524264A patent/JP6906515B2/ja not_active Expired - Fee Related
- 2016-11-18 BR BR112018010156A patent/BR112018010156A8/pt active Search and Examination
- 2016-11-18 ES ES16801740T patent/ES2781374T3/es active Active
- 2016-11-18 EP EP16801740.8A patent/EP3377894B1/en active Active
- 2016-11-18 US US15/777,651 patent/US10718760B2/en active Active
- 2016-11-18 WO PCT/EP2016/078131 patent/WO2017085251A1/en not_active Ceased
- 2016-11-18 KR KR1020187017419A patent/KR20180082588A/ko not_active Ceased
-
2018
- 2018-05-14 IL IL259328A patent/IL259328B/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| US10718760B2 (en) | 2020-07-21 |
| BR112018010156A2 (en) | 2018-11-21 |
| BR112018010156A8 (pt) | 2019-02-26 |
| CN108431601A (zh) | 2018-08-21 |
| US20180348210A1 (en) | 2018-12-06 |
| CN108431601B (zh) | 2021-04-27 |
| KR20180082588A (ko) | 2018-07-18 |
| WO2017085251A1 (en) | 2017-05-26 |
| IL259328A (en) | 2018-07-31 |
| EP3377894B1 (en) | 2019-12-25 |
| IL259328B (en) | 2020-06-30 |
| EP3377894A1 (en) | 2018-09-26 |
| JP6906515B2 (ja) | 2021-07-21 |
| HK1255013A1 (zh) | 2019-08-02 |
| JP2018537668A (ja) | 2018-12-20 |
| ES2781374T3 (es) | 2020-09-01 |
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