DK339685A - 2-phenylalkyl-3-aminoalkyl-4(3h)-quinazolinoner og fremgangsmaade til fremstilling deraf - Google Patents

2-phenylalkyl-3-aminoalkyl-4(3h)-quinazolinoner og fremgangsmaade til fremstilling deraf Download PDF

Info

Publication number: DK339685A
Authority: DK; Denmark
Prior art keywords: group; carbon atoms; sub; sup; integer
Prior art date: 1984-07-26

Application number

DK339685A

Other languages

English (en)

Other versions

DK339685D0 (da

Inventor

Tetsuo Sekiya

Mikio Tsutsui

Daijiro Horii

Akira Ishikawa

Original Assignee

Mitsubishi Yuka Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-07-26

Filing date

1985-07-25

Publication date

1986-01-27

1985-07-25 Application filed by Mitsubishi Yuka Pharma filed Critical Mitsubishi Yuka Pharma

1985-07-25 Publication of DK339685D0 publication Critical patent/DK339685D0/da

1986-01-27 Publication of DK339685A publication Critical patent/DK339685A/da

Links

238000000034 method Methods 0.000 title 1
125000004432 carbon atom Chemical group C* 0.000 abstract 9
125000000217 alkyl group Chemical group 0.000 abstract 5
150000001875 compounds Chemical class 0.000 abstract 4
125000003545 alkoxy group Chemical group 0.000 abstract 3
125000005843 halogen group Chemical group 0.000 abstract 3
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
125000000051 benzyloxy group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])O* 0.000 abstract 2
239000002253 acid Substances 0.000 abstract 1
239000004480 active ingredient Substances 0.000 abstract 1
125000002947 alkylene group Chemical group 0.000 abstract 1
125000003277 amino group Chemical group 0.000 abstract 1
230000003276 anti-hypertensive effect Effects 0.000 abstract 1
230000002213 calciumantagonistic effect Effects 0.000 abstract 1
125000004122 cyclic group Chemical group 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
229910052757 nitrogen Inorganic materials 0.000 abstract 1
125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
125000000951 phenoxy group Chemical group [H]C1=C([H])C([H])=C(O*)C([H])=C1[H] 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
230000000304 vasodilatating effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/88—Oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/88—Oxygen atoms
- C07D239/90—Oxygen atoms with acyclic radicals attached in position 2 or 3
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Endocrinology (AREA)
Rheumatology (AREA)
Pulmonology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

DK339685A 1984-07-26 1985-07-25 2-phenylalkyl-3-aminoalkyl-4(3h)-quinazolinoner og fremgangsmaade til fremstilling deraf DK339685A (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP15408684A JPS6136273A (ja)	1984-07-26	1984-07-26	２−フエニルアルキル−４（３ｈ）−キナゾリノン誘導体

Publications (2)

Publication Number	Publication Date
DK339685D0 DK339685D0 (da)	1985-07-25
DK339685A true DK339685A (da)	1986-01-27

Family

ID=15576584

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK339685A DK339685A (da)	1984-07-26	1985-07-25	2-phenylalkyl-3-aminoalkyl-4(3h)-quinazolinoner og fremgangsmaade til fremstilling deraf

Country Status (9)

Country	Link
US (1)	US4668682A (da)
EP (1)	EP0169537B1 (da)
JP (1)	JPS6136273A (da)
KR (1)	KR860001078A (da)
AT (1)	ATE49199T1 (da)
CA (1)	CA1266266A (da)
DE (1)	DE3575132D1 (da)
DK (1)	DK339685A (da)
HU (1)	HU194836B (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2037630C (en) *	1990-03-07	2001-07-03	Akira Morimoto	Nitrogen-containing heterocylic compounds, their production and use
GB9116207D0 (en) *	1991-07-26	1991-09-11	Ici Plc	Novel compounds
US5430148A (en) *	1992-03-31	1995-07-04	Agouron Pharmaceuticals, Inc.	Antiproliferative quinazolines
IT1266992B1 (it) *	1993-04-16	1997-01-24	Alfa Wassermann Spa	Composti eterociclici, a struttura correlabile alle banzammidi, attivi nelle patologie gastro-intestinali, ad attivita' procinetica ed
US5756502A (en) *	1994-08-08	1998-05-26	Warner-Lambert Company	Quinazolinone derivatives as cholyecystokinin (CCK) ligands
DE19501481A1 (de) *	1995-01-19	1996-07-25	Bayer Ag	2,8-Disubstituierte Chinazolinone
WO1997009301A1 (en) *	1995-09-07	1997-03-13	Kissei Pharmaceutical Co., Ltd.	2-acylaminobenzamide derivatives and preventive and remedy for diseases caused by the supermultiplication of vascular intimal cells
EP0903344B1 (en) *	1997-08-21	2011-01-26	Shiseido Co., Ltd.	Quinazolin-4-one derivatives, their preparation and their use as hair growth promoters or in external compositions for skin
US6444816B1 (en)	1997-10-27	2002-09-03	Dr. Reddy's Research Foundation	Fused 7-oxo-pyrimidinyl compounds, preparation, composition and use thereof
US6337332B1 (en) *	1998-09-17	2002-01-08	Pfizer Inc.	Neuropeptide Y receptor antagonists
US6890930B1 (en)	1999-09-28	2005-05-10	3-Dimensional Pharmaceuticals, Inc.	Quinazolinones
CA2385921A1 (en) *	1999-09-28	2001-04-05	Merck Patent Gesellschaft Mit Beschraenkter Haftung	Quinazolinones
AU9650201A (en) *	2000-10-02	2002-04-15	Molecular Probes Inc	Reagents for labeling biomolecules having aldehyde or ketone moieties
EP1389103A4 (en) *	2001-04-23	2005-09-14	Univ Virginia	SYNTHESIS AND EVALUATION OF NEW PHTHALIMIDE COPIES AS ANTIANGIOGENIC AGENTS
US7053216B2 (en) *	2001-11-19	2006-05-30	Iconix Pharmaceuticals, Inc.	Modulators of Rho C activity
PL377474A1 (pl) *	2002-12-13	2006-02-06	F. Hoffmann-La Roche Ag	Pochodne 3H-chinazolin-4-onu
KR100610731B1 (ko) *	2004-02-24	2006-08-09	한국과학기술연구원	Ｔ-형 칼슘 채널 차단제로서 유용한 ３,４-디히드로퀴나졸린유도체 및 그의 제조 방법

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2020234A1 (de) *	1970-04-25	1971-11-18	Cassella Farbwerke Mainkur Ag	Basisch substituierte Derivate des 4(3H)-Chinazolinons

1984
- 1984-07-26 JP JP15408684A patent/JPS6136273A/ja active Pending
1985
- 1985-07-10 US US06/753,708 patent/US4668682A/en not_active Expired - Fee Related
- 1985-07-15 CA CA000486793A patent/CA1266266A/en not_active Expired - Lifetime
- 1985-07-23 AT AT85109193T patent/ATE49199T1/de not_active IP Right Cessation
- 1985-07-23 DE DE8585109193T patent/DE3575132D1/de not_active Expired - Lifetime
- 1985-07-23 EP EP85109193A patent/EP0169537B1/en not_active Expired - Lifetime
- 1985-07-25 KR KR1019850005302A patent/KR860001078A/ko not_active Withdrawn
- 1985-07-25 DK DK339685A patent/DK339685A/da not_active Application Discontinuation
- 1985-07-26 HU HU852850A patent/HU194836B/hu not_active IP Right Cessation

Also Published As

Publication number	Publication date
HUT39166A (en)	1986-08-28
EP0169537B1 (en)	1990-01-03
ATE49199T1 (de)	1990-01-15
CA1266266A (en)	1990-02-27
HU194836B (en)	1988-03-28
DE3575132D1 (de)	1990-02-08
EP0169537A3 (en)	1987-03-25
JPS6136273A (ja)	1986-02-20
DK339685D0 (da)	1985-07-25
KR860001078A (ko)	1986-02-22
EP0169537A2 (en)	1986-01-29
US4668682A (en)	1987-05-26

Legal Events

Date	Code	Title	Description
1992-03-02	AHS	Application shelved for other reasons than non-payment

Publication	Publication Date	Title
DK339685D0 (da)	1985-07-25	2-phenylalkyl-3-aminoalkyl-4(3h)-quinazolinoner og fremgangsmaade til fremstilling deraf
DK250386D0 (da)	1986-05-28	Fremgangsmaade til fremstilling af heterocycliske forbindelser
DK602589A (da)	1990-05-31	Quinazolinonderivater
ATE37179T1 (de)	1988-09-15	Dihydropyridazinone.
IL75583A0 (en)	1985-10-31	Pyrazole analogs of mevalonolactone and derivatives thereof,their preparation and pharmaceutical compositions containing them
ES534505A0 (es)	1986-11-16	Un procedimiento para la preparacion de compuestos de 1, 4-dihidropiridina
ATE66674T1 (de)	1991-09-15	Dihydropyridin-derivate, verfahren zu ihrer herstellung, diese enthaltende pharmazeutische zusammensetzungen, und verfahren zur herstellung dieser zusammensetzungen.
DE69001111D1 (de)	1993-04-22	Antikrebs-zusammensetzung.
EP0219852A3 (en)	1987-11-25	Chartreusin derivatives, salts thereof, antitumorous compositions containing the same, and processes for producing the same
GR79148B (da)	1984-10-02
ES8706610A1 (es)	1987-07-01	Proceso para preparar un derivado de aminoalcohol.
DE3576499D1 (en)	1990-04-19	Dihydropyridine.
DE69007356D1 (de)	1994-04-21	Zyklisches Tetrapeptid und Verfahren zu dessen Herstellung.
ES557597A0 (es)	1988-02-16	Procedimiento para preparar acidos hexenoicos
ES8608500A1 (es)	1986-06-16	Un procedimiento para preparar nuevas 1,2,4-tiadiazinas
DK162785D0 (da)	1985-04-11	1-cyklohexyl-3,4-dihydroisoquinolinderivater, fremgangsmaade til fremstilling deraf og farmaceutiske praeparater indeholdende dem
EP0218195A3 (en)	1988-01-07	Bis(dibenzo[b,d]pyranyloxy)propanes