DK3452475T3 - Tetrahydropyridodiazepinforbindelser til at behandle smerte og smerterelaterede tilstande - Google Patents
Tetrahydropyridodiazepinforbindelser til at behandle smerte og smerterelaterede tilstande Download PDFInfo
- Publication number
- DK3452475T3 DK3452475T3 DK17721680.1T DK17721680T DK3452475T3 DK 3452475 T3 DK3452475 T3 DK 3452475T3 DK 17721680 T DK17721680 T DK 17721680T DK 3452475 T3 DK3452475 T3 DK 3452475T3
- Authority
- DK
- Denmark
- Prior art keywords
- pain
- tetrahydropyridodiazepine
- compounds
- related conditions
- treat
- Prior art date
Links
- UVQZQVBFEIHXDX-UHFFFAOYSA-N 2,3,4,5-tetrahydro-1H-pyrido[3,2-c]diazepine Chemical class N1NCCCC2=C1C=CC=N2 UVQZQVBFEIHXDX-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16382199 | 2016-05-06 | ||
| PCT/EP2017/060780 WO2017191304A1 (en) | 2016-05-06 | 2017-05-05 | Tetrahydropyrimidodiazepine and tetrahydropyridodiazepine compounds for treating pain and pain related conditions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3452475T3 true DK3452475T3 (da) | 2020-04-27 |
Family
ID=56024209
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK17721680.1T DK3452475T3 (da) | 2016-05-06 | 2017-05-05 | Tetrahydropyridodiazepinforbindelser til at behandle smerte og smerterelaterede tilstande |
Country Status (33)
| Country | Link |
|---|---|
| US (1) | US10590140B2 (da) |
| EP (1) | EP3452475B1 (da) |
| JP (1) | JP6926197B2 (da) |
| KR (1) | KR20190024876A (da) |
| CN (1) | CN109526220B (da) |
| AR (1) | AR108387A1 (da) |
| AU (1) | AU2017260305B2 (da) |
| BR (1) | BR112018072755A2 (da) |
| CA (1) | CA3023379A1 (da) |
| CO (1) | CO2018012002A2 (da) |
| CY (1) | CY1123231T1 (da) |
| DK (1) | DK3452475T3 (da) |
| ES (1) | ES2789676T3 (da) |
| HR (1) | HRP20200668T1 (da) |
| HU (1) | HUE051829T2 (da) |
| IL (1) | IL262825A (da) |
| LT (1) | LT3452475T (da) |
| ME (1) | ME03726B (da) |
| MX (1) | MX383520B (da) |
| MY (1) | MY196791A (da) |
| PH (1) | PH12018502337A1 (da) |
| PL (1) | PL3452475T3 (da) |
| PT (1) | PT3452475T (da) |
| RS (1) | RS60528B1 (da) |
| RU (1) | RU2018141084A (da) |
| SG (1) | SG11201809799WA (da) |
| SI (1) | SI3452475T1 (da) |
| SM (1) | SMT202000365T1 (da) |
| TN (1) | TN2018000372A1 (da) |
| TW (1) | TWI736619B (da) |
| UA (1) | UA123789C2 (da) |
| WO (1) | WO2017191304A1 (da) |
| ZA (1) | ZA201807653B (da) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019076904A1 (en) * | 2017-10-16 | 2019-04-25 | Esteve Pharmaceuticals, S.A. | PROPANAMINE DERIVATIVES FOR THE TREATMENT OF PAIN AND PAIN DISEASES ASSOCIATED WITH PAIN |
| JP2021500416A (ja) * | 2017-10-27 | 2021-01-07 | エステベ ファーマスーティカルズ，ソシエダッド アノニマ | 疼痛及び疼痛関連状態を治療するための新規アルコキシアミノ誘導体 |
| TW201938154A (zh) * | 2017-12-04 | 2019-10-01 | 西班牙商艾斯提夫製藥股份有限公司 | 具有抗疼痛活性之鄰苯氧基及鄰苄氧基丙胺基衍生物 |
| WO2019115008A1 (en) * | 2017-12-12 | 2019-06-20 | Esteve Pharmaceuticals, S.A. | Dialkylaminoarylpiperidinyl-o-phenoxy and o-benzyloxypropylamino derivatives having multimodal activity against pain |
| WO2019149919A1 (en) * | 2018-02-05 | 2019-08-08 | Esteve Pharmaceuticals, S.A. | Aminopropoxypiperidinylamido derivatives having multimodal activity against pain |
| WO2020089263A1 (en) * | 2018-10-31 | 2020-05-07 | Esteve Pharmaceuticals, S.A. | Optionally nitrogenated isoquinolin-1(2h)-ones and 1h-isochromen- 1-ones for treating pain and pain related conditions |
| US20210395254A1 (en) * | 2018-11-02 | 2021-12-23 | Esteve Pharmaceuticals, S.A. | New tetrahydropyrimidodiazepin and tetrahydropyridodiazepin compounds for treating pain and pain related conditions |
| US20210395249A1 (en) * | 2018-11-02 | 2021-12-23 | Esteve Pharmaceuticals, S.A. | New alkoxyaminopyridine derivatives for treating pain and pain related conditions |
| JP7658578B2 (ja) | 2019-02-28 | 2025-04-08 | 国立大学法人大阪大学 | タンパク質及び／又はペプチド修飾用分子 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL155035A0 (en) * | 2000-09-27 | 2003-10-31 | Ajinomoto Kk | Benzodiazepine derivatives |
| WO2004002462A2 (en) | 2002-06-27 | 2004-01-08 | Warner-Lambert Company Llc | Use of an alpha2delta ligand such as gabapentin or pregabalin for treating ttention deficit hyperactivity disorder |
| JPWO2005085210A1 (ja) * | 2004-03-10 | 2008-01-17 | 小野薬品工業株式会社 | ニトリル化合物およびその化合物を有効成分として含有する医薬組成物 |
| ZA200806871B (en) * | 2006-02-14 | 2009-10-28 | Vertex Pharma | Dihydrodiazepines useful as inhibitors of protein kinases |
| TW200914457A (en) * | 2007-05-31 | 2009-04-01 | Kyowa Hakko Kogyo Kk | Pyrimidodiazepinone derivative |
| UY32622A (es) * | 2009-05-12 | 2010-12-31 | Astrazeneca Ab | Nuevos compuestos para el tratamiento de patologías relacionadas con ab(beta) |
-
2017
- 2017-05-05 MY MYPI2018704135A patent/MY196791A/en unknown
- 2017-05-05 SI SI201730239T patent/SI3452475T1/sl unknown
- 2017-05-05 HU HUE17721680A patent/HUE051829T2/hu unknown
- 2017-05-05 ES ES17721680T patent/ES2789676T3/es active Active
- 2017-05-05 HR HRP20200668TT patent/HRP20200668T1/hr unknown
- 2017-05-05 JP JP2019510471A patent/JP6926197B2/ja not_active Expired - Fee Related
- 2017-05-05 CN CN201780042378.XA patent/CN109526220B/zh not_active Expired - Fee Related
- 2017-05-05 TW TW106114980A patent/TWI736619B/zh not_active IP Right Cessation
- 2017-05-05 DK DK17721680.1T patent/DK3452475T3/da active
- 2017-05-05 AU AU2017260305A patent/AU2017260305B2/en not_active Ceased
- 2017-05-05 RU RU2018141084A patent/RU2018141084A/ru unknown
- 2017-05-05 ME MEP-2020-101A patent/ME03726B/me unknown
- 2017-05-05 WO PCT/EP2017/060780 patent/WO2017191304A1/en not_active Ceased
- 2017-05-05 LT LTEP17721680.1T patent/LT3452475T/lt unknown
- 2017-05-05 US US16/098,244 patent/US10590140B2/en active Active
- 2017-05-05 PT PT177216801T patent/PT3452475T/pt unknown
- 2017-05-05 KR KR1020187032195A patent/KR20190024876A/ko not_active Ceased
- 2017-05-05 TN TNP/2018/000372A patent/TN2018000372A1/en unknown
- 2017-05-05 SM SM20200365T patent/SMT202000365T1/it unknown
- 2017-05-05 RS RS20200595A patent/RS60528B1/sr unknown
- 2017-05-05 EP EP17721680.1A patent/EP3452475B1/en active Active
- 2017-05-05 CA CA3023379A patent/CA3023379A1/en not_active Abandoned
- 2017-05-05 MX MX2018013471A patent/MX383520B/es unknown
- 2017-05-05 UA UAA201811326A patent/UA123789C2/uk unknown
- 2017-05-05 PL PL17721680T patent/PL3452475T3/pl unknown
- 2017-05-05 AR ARP170101172A patent/AR108387A1/es unknown
- 2017-05-05 BR BR112018072755-5A patent/BR112018072755A2/pt not_active IP Right Cessation
- 2017-05-05 SG SG11201809799WA patent/SG11201809799WA/en unknown
-
2018
- 2018-11-06 IL IL262825A patent/IL262825A/en unknown
- 2018-11-06 PH PH12018502337A patent/PH12018502337A1/en unknown
- 2018-11-14 ZA ZA2018/07653A patent/ZA201807653B/en unknown
- 2018-11-29 CO CONC2018/0012002A patent/CO2018012002A2/es unknown
-
2020
- 2020-05-25 CY CY20201100472T patent/CY1123231T1/el unknown
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