DK3487625T3 - Alsidigt, strækbart 3d-mikromiljø til anordninger til mikrochip-organer fremstillet med almindelig siliciumteknologi - Google Patents

Alsidigt, strækbart 3d-mikromiljø til anordninger til mikrochip-organer fremstillet med almindelig siliciumteknologi Download PDF

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Publication number
DK3487625T3
DK3487625T3 DK17758965.2T DK17758965T DK3487625T3 DK 3487625 T3 DK3487625 T3 DK 3487625T3 DK 17758965 T DK17758965 T DK 17758965T DK 3487625 T3 DK3487625 T3 DK 3487625T3
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Denmark
Prior art keywords
microchip
extensible
versatile
devices manufactured
organic devices
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DK17758965.2T
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English (en)
Inventor
Nikolas Gaio
Solano William Fausto Quirã¿S
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Biond Solutions B V
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502707Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/02Form or structure of the vessel
    • C12M23/16Microfluidic devices; Capillary tubes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/20Material Coatings
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/22Transparent or translucent parts
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/12Specific details about manufacturing devices
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/0627Sensor or part of a sensor is integrated
    • B01L2300/0645Electrodes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/0627Sensor or part of a sensor is integrated
    • B01L2300/0663Whole sensors
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0887Laminated structure
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0893Geometry, shape and general structure having a very large number of wells, microfabricated wells
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/12Specific details about materials
    • B01L2300/123Flexible; Elastomeric
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/18Means for temperature control
    • B01L2300/1805Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • B01L2300/1822Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using Peltier elements
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/18Means for temperature control
    • B01L2300/1805Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • B01L2300/1827Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using resistive heater

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micromachines (AREA)
DK17758965.2T 2016-07-25 2017-07-20 Alsidigt, strækbart 3d-mikromiljø til anordninger til mikrochip-organer fremstillet med almindelig siliciumteknologi DK3487625T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL2017227A NL2017227B1 (en) 2016-07-25 2016-07-25 Versatile 3D Stretchable Micro-Environment for Organ-on-Chip Devices Fabricated with Standard Silicon Technology
PCT/NL2017/050492 WO2018021906A1 (en) 2016-07-25 2017-07-20 Versatile 3d stretchable micro-environment for organ-on-chip devices fabricated with standard silicon technology

Publications (1)

Publication Number Publication Date
DK3487625T3 true DK3487625T3 (da) 2020-06-02

Family

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Family Applications (1)

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DK17758965.2T DK3487625T3 (da) 2016-07-25 2017-07-20 Alsidigt, strækbart 3d-mikromiljø til anordninger til mikrochip-organer fremstillet med almindelig siliciumteknologi

Country Status (10)

Country Link
US (1) US11565250B2 (da)
EP (1) EP3487625B1 (da)
JP (2) JP2019521699A (da)
KR (1) KR102572442B1 (da)
CN (1) CN109689214B (da)
CA (1) CA3068696C (da)
DK (1) DK3487625T3 (da)
ES (1) ES2794876T3 (da)
NL (1) NL2017227B1 (da)
WO (1) WO2018021906A1 (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3765870B1 (en) 2018-03-15 2025-05-07 The Regents of the University of California Adaptive materials and systems for manipulation of electromagnetic radiation
CN111971383B (zh) * 2018-05-21 2022-02-22 深圳华大生命科学研究院 一种仿生肠道器官芯片及其制备方法和应用
EP3887147B1 (en) 2018-11-27 2026-02-11 The Regents of the University of California Composite materials with adjustable spectral properties
EP3798300A1 (en) 2019-09-24 2021-03-31 Koninklijke Philips N.V. Cell culturing materials
KR102222074B1 (ko) 2020-04-28 2021-03-03 (주)아크에이르 장기 칩 시험 시스템
NL2025441B1 (en) * 2020-04-28 2021-11-09 Biond Solutions B V All-in-one microchamber for 3D muscular tissues
EP3912722A1 (en) * 2020-05-21 2021-11-24 Biothink Technologies S.L. Laboratory integrated on a chip and manufacturing procedure
US12027636B2 (en) 2020-11-19 2024-07-02 Maxeon Solar Pte. Ltd. Protection coating for solar cell wafers
CN115125122A (zh) * 2022-06-06 2022-09-30 太原理工大学 单细胞三维动态力学刺激装置
KR20240130384A (ko) 2023-02-22 2024-08-29 한국과학기술원 미세유체 칩을 이용하는 세포 손상의 회복에 대한 시험 장치 및 시험 방법
KR102926981B1 (ko) 2023-10-30 2026-02-11 포항공과대학교 산학협력단 3d 잉크젯 바이오 프린팅된 폐 조직이 삽입된 미세유체 칩 시스템 및 그 제조 방법
CN121136817A (zh) * 2025-09-05 2025-12-16 甬江实验室 芯片组件及其制备方法

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JP2001281233A (ja) * 2000-03-28 2001-10-10 Inst Of Physical & Chemical Res 水性分配用マイクロチップおよびそれを用いた水性分配方法
US7790443B2 (en) * 2002-08-27 2010-09-07 Vanderbilt University Bioreactors with substance injection capacity
US6878271B2 (en) * 2002-09-09 2005-04-12 Cytonome, Inc. Implementation of microfluidic components in a microfluidic system
CN101405084B (zh) * 2006-03-20 2011-11-16 皇家飞利浦电子股份有限公司 用于电子微流体设备的系统级封装台
US9403126B2 (en) * 2007-01-10 2016-08-02 The Regents Of The University Of Michigan Ultrafiltration membrane, device, bioartificial organ, and related methods
US8058630B2 (en) * 2009-01-16 2011-11-15 Fluidigm Corporation Microfluidic devices and methods
CN103201624B (zh) * 2010-08-05 2015-06-17 皇家飞利浦电子股份有限公司 包含心肌细胞的装置、制造方法和测量方法
JP6033959B2 (ja) * 2013-01-09 2016-11-30 テカン・トレーディング・アクチェンゲゼルシャフトTECAN Trading AG マイクロ流体システム用使い捨てカートリッジ
CN203508047U (zh) * 2013-08-23 2014-04-02 许毅 自动切换通道的纸基微流体装置及其制成的生化检测装置
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Also Published As

Publication number Publication date
JP7257565B2 (ja) 2023-04-13
CA3068696C (en) 2023-02-14
NL2017227B1 (en) 2018-01-31
EP3487625B1 (en) 2020-04-08
ES2794876T3 (es) 2020-11-19
CN109689214A (zh) 2019-04-26
EP3487625A1 (en) 2019-05-29
KR20190032413A (ko) 2019-03-27
JP2022063879A (ja) 2022-04-22
JP2019521699A (ja) 2019-08-08
WO2018021906A1 (en) 2018-02-01
KR102572442B1 (ko) 2023-08-29
CN109689214B (zh) 2022-12-23
US11565250B2 (en) 2023-01-31
CA3068696A1 (en) 2018-02-01
US20190168218A1 (en) 2019-06-06

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