DK3511015T3 - Genetisk stabil levende svækket respiratorisk syncytialvirusvaccine og fremstilling deraf - Google Patents
Genetisk stabil levende svækket respiratorisk syncytialvirusvaccine og fremstilling deraf Download PDFInfo
- Publication number
- DK3511015T3 DK3511015T3 DK19150800.1T DK19150800T DK3511015T3 DK 3511015 T3 DK3511015 T3 DK 3511015T3 DK 19150800 T DK19150800 T DK 19150800T DK 3511015 T3 DK3511015 T3 DK 3511015T3
- Authority
- DK
- Denmark
- Prior art keywords
- manufacturing
- respiratory syncytial
- syncytial virus
- virus vaccine
- genetically stable
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
- C12N2760/18521—Viruses as such, e.g. new isolates, mutants or their genomic sequences
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
- C12N2760/18522—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
- C12N2760/18534—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
- C12N2760/18561—Methods of inactivation or attenuation
- C12N2760/18562—Methods of inactivation or attenuation by genetic engineering
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Pulmonology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261624010P | 2012-04-13 | 2012-04-13 | |
| EP13712641.3A EP2836231B1 (en) | 2012-04-13 | 2013-03-13 | Genetically stable live attenuated respiratory syncytial virus vaccine and its production |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK3511015T3 true DK3511015T3 (da) | 2021-03-15 |
| DK3511015T5 DK3511015T5 (da) | 2025-12-01 |
Family
ID=47998536
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK19150800.1T DK3511015T5 (da) | 2012-04-13 | 2013-03-13 | Genetisk stabil levende svækket respiratorisk syncytialvirusvaccine og fremstilling deraf |
Country Status (8)
| Country | Link |
|---|---|
| US (4) | US9624475B2 (da) |
| EP (3) | EP2836231B1 (da) |
| DK (1) | DK3511015T5 (da) |
| ES (1) | ES2863477T3 (da) |
| FI (1) | FI3511015T9 (da) |
| PL (1) | PL3511015T3 (da) |
| PT (1) | PT3511015T (da) |
| WO (1) | WO2013154728A1 (da) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL3511015T3 (pl) * | 2012-04-13 | 2021-09-13 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Genetycznie stabilna żywa atenuowana szczepionka przeciw syncytialnemu wirusowi oddechowemu i jej wytwarzanie |
| US10947512B2 (en) | 2015-08-14 | 2021-03-16 | Research Institute At Nationwide Children's Hospital | Respiratory syncytial virus having altered NS1 protein function and related materials and methods |
| WO2017100759A1 (en) * | 2015-12-11 | 2017-06-15 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Recombinant respiratory syncytial virus strains with mutations in the m2-2 orf providing a range of attenuation phenotypes |
| US20230279362A1 (en) * | 2020-06-05 | 2023-09-07 | The United States Of America, As Represented By The Secretary, Department Of Health And Human | Live attenuated respiratory syncytial virus |
| AU2023219791A1 (en) | 2022-02-14 | 2024-08-22 | University Of Georgia Research Foundation, Inc. | Pan-pneumovirus vaccine compositions and methods of use thereof. |
| CN114574521B (zh) * | 2022-03-03 | 2023-09-12 | 山东中医药大学 | 一种基于平衡补偿的重组流感病毒构建方法 |
| EP4709418A1 (en) | 2023-05-11 | 2026-03-18 | Sanofi Pasteur Inc. | Respiratory syncytial virus vaccine and methods of use |
| AU2024380679A1 (en) | 2023-11-17 | 2026-07-02 | Sanofi Vaccines US Inc. | Trehalose vaccine formulation |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3224404A1 (de) | 1982-06-30 | 1984-01-05 | LuK Lamellen und Kupplungsbau GmbH, 7580 Bühl | Reibungskupplung sowie verfahren zu deren montage |
| IL105456A (en) * | 1992-04-21 | 1996-12-05 | American Home Prod | Vaccines of attenuated respiratory syncytial virus |
| US7846455B2 (en) * | 1996-07-15 | 2010-12-07 | The United States Of America As Represented By The Department Of Health And Human Services | Attenuated chimeric respiratory syncytial virus |
| US6713066B1 (en) * | 1996-07-15 | 2004-03-30 | The United States Of America As Represented By The Department Of Health And Human Services | Production of attenuated respiratory syncytial virus vaccines involving modification of M2 ORF2 |
| EP0912724B1 (en) * | 1996-07-15 | 2009-12-09 | The Government of The United States of America, as represented by The Department of Health and Human Services | Production of attenuated respiratory syncytial virus vaccines from cloned nucleotide sequences |
| CN101260386A (zh) | 1999-07-09 | 2008-09-10 | 美国政府健康及人类服务部 | 减毒的人-牛嵌合呼吸道合胞病毒疫苗的生产 |
| PL3511015T3 (pl) * | 2012-04-13 | 2021-09-13 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Genetycznie stabilna żywa atenuowana szczepionka przeciw syncytialnemu wirusowi oddechowemu i jej wytwarzanie |
-
2013
- 2013-03-13 PL PL19150800T patent/PL3511015T3/pl unknown
- 2013-03-13 EP EP13712641.3A patent/EP2836231B1/en active Active
- 2013-03-13 EP EP19150800.1A patent/EP3511015B9/en active Active
- 2013-03-13 US US14/394,226 patent/US9624475B2/en active Active
- 2013-03-13 ES ES19150800T patent/ES2863477T3/es active Active
- 2013-03-13 FI FIEP19150800.1T patent/FI3511015T9/fi unknown
- 2013-03-13 WO PCT/US2013/030836 patent/WO2013154728A1/en not_active Ceased
- 2013-03-13 DK DK19150800.1T patent/DK3511015T5/da active
- 2013-03-13 EP EP20217105.4A patent/EP3875112A1/en active Pending
- 2013-03-13 PT PT191508001T patent/PT3511015T/pt unknown
-
2017
- 2017-03-10 US US15/455,438 patent/US10307476B2/en active Active
-
2019
- 2019-05-29 US US16/425,725 patent/US10980872B2/en active Active
-
2021
- 2021-04-07 US US17/224,819 patent/US20210330782A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US9624475B2 (en) | 2017-04-18 |
| EP3511015A1 (en) | 2019-07-17 |
| US10307476B2 (en) | 2019-06-04 |
| ES2863477T3 (es) | 2021-10-11 |
| EP3511015B1 (en) | 2020-12-30 |
| US20150118732A1 (en) | 2015-04-30 |
| EP2836231B1 (en) | 2019-01-09 |
| EP2836231A1 (en) | 2015-02-18 |
| US10980872B2 (en) | 2021-04-20 |
| US20170189520A1 (en) | 2017-07-06 |
| PT3511015T (pt) | 2021-04-05 |
| EP3511015B9 (en) | 2025-10-22 |
| US20210330782A1 (en) | 2021-10-28 |
| US20190282690A1 (en) | 2019-09-19 |
| WO2013154728A1 (en) | 2013-10-17 |
| DK3511015T5 (da) | 2025-12-01 |
| ES2863477T9 (en) | 2025-12-19 |
| EP3875112A1 (en) | 2021-09-08 |
| PL3511015T3 (pl) | 2021-09-13 |
| FI3511015T9 (fi) | 2025-09-11 |
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