DK3536346T3 - PET tracer til afbildning af neuroendocrine tumorer - Google Patents

PET tracer til afbildning af neuroendocrine tumorer Download PDF

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Publication number
DK3536346T3
DK3536346T3 DK19164889.8T DK19164889T DK3536346T3 DK 3536346 T3 DK3536346 T3 DK 3536346T3 DK 19164889 T DK19164889 T DK 19164889T DK 3536346 T3 DK3536346 T3 DK 3536346T3
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DK
Denmark
Prior art keywords
neuroendocrine tumors
pet tracer
imaging neuroendocrine
imaging
tracer
Prior art date
Application number
DK19164889.8T
Other languages
English (en)
Inventor
Andreas Kjaer
Ulrich Knigge
Liselotte Højgaard
Palle Rasmussen
Original Assignee
Somscan Aps
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Somscan Aps filed Critical Somscan Aps
Application granted granted Critical
Publication of DK3536346T3 publication Critical patent/DK3536346T3/da

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0474Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0482Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group chelates from cyclic ligands, e.g. DOTA
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/083Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the peptide being octreotide or a somatostatin-receptor-binding peptide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00Preparations for use in therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00Preparations for testing in vivo
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/04X-ray contrast preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nuclear Medicine (AREA)
DK19164889.8T 2011-08-31 2012-08-23 PET tracer til afbildning af neuroendocrine tumorer DK3536346T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA201100654 2011-08-31
EP12828526.9A EP2750717B1 (en) 2011-08-31 2012-08-23 Pet tracer for imaging of neuroendocrine tumors

Publications (1)

Publication Number Publication Date
DK3536346T3 true DK3536346T3 (da) 2021-01-25

Family

ID=47755353

Family Applications (1)

Application Number Title Priority Date Filing Date
DK19164889.8T DK3536346T3 (da) 2011-08-31 2012-08-23 PET tracer til afbildning af neuroendocrine tumorer

Country Status (7)

Country Link
US (3) US10159759B2 (da)
EP (2) EP2750717B1 (da)
DK (1) DK3536346T3 (da)
ES (2) ES2732823T3 (da)
HU (2) HUE044625T2 (da)
PL (2) PL2750717T3 (da)
WO (1) WO2013029616A1 (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2750717B1 (en) * 2011-08-31 2019-03-27 Somscan ApS Pet tracer for imaging of neuroendocrine tumors
JP2015532636A (ja) * 2012-05-08 2015-11-12 リグスホスピタレト 部位特異的uPAR標的化のための177−Lu標識ペプチド
GB201219403D0 (en) * 2012-10-29 2012-12-12 Uni I Olso Method for improved estimation of tracer uptake in physiological image volumes
ES2972124T3 (es) * 2012-12-03 2024-06-11 Curasight As Péptidos marcados con un radionúclido que emite positrones para obtención de imágenes de PET del uPAR humana
WO2014169073A1 (en) 2013-04-09 2014-10-16 Massachusetts Institute Of Technology Drug delivery polymer and uses thereof
DK3193945T3 (da) * 2014-09-17 2020-11-16 Fluoguide As Upar-målrettende peptid til anvendelse ved peroperativ optisk billeddannelse af invasiv cancer
HRP20231458T1 (hr) * 2017-01-12 2024-05-10 Radiomedix Inc. Liječenje stanica raka koje prekomjerno eksprimiraju receptore za somatostatin primjenom derivata oktreotida keliranih sa radioizotopima
CN112423744A (zh) 2018-04-11 2021-02-26 透明医药有限公司 用于放射疗法和诊断成像的制剂和试剂盒
WO2019240884A2 (en) 2018-04-27 2019-12-19 University Of Iowa Research Foundation Compositions for chelating metals at low temperatures
TWI878344B (zh) 2019-09-17 2025-04-01 瑞士商諾華公司 放射性標記grpr拮抗劑之方法及其套組
CA3166142A1 (en) * 2020-01-29 2021-08-05 Dongyoul Lee Structural optimization method to improve the theranostic performance of peptide receptor-targeted radionuclide therapy for cancers
IL297323A (en) 2020-04-29 2022-12-01 Novartis Ag Methods for radiological labeling of psma-binding ligands and their kits
TWI905175B (zh) 2020-04-29 2025-11-21 瑞士商諾華公司 放射性標記psma結合配位體的方法及其套組
AU2021336987A1 (en) * 2020-09-03 2023-04-06 Curium Us Llc Radiolabeling and formulation for scale up of 64Cu-dotatate
US11541134B1 (en) 2021-08-02 2023-01-03 Rayzebio, Inc. Stabilized compositions of radionuclides and uses thereof
EP4197561A1 (en) * 2021-12-15 2023-06-21 Curasight A/S Urokinase-type plasminogen activator receptor (upar)-pet/ct in neuroendocrine neoplams
KR20250073273A (ko) 2022-09-23 2025-05-27 누클리디움 아게 고순도 구리 방사성 의약 조성물 및 이의 진단 및 치료 용도
TW202426433A (zh) 2022-09-23 2024-07-01 瑞士商紐利迪姆股份公司 成纖維細胞活化蛋白(fap)抑制劑、fap結合物及其診斷與治療用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7122622B2 (en) * 2002-04-16 2006-10-17 Biosynthema Inc. Peptide compounds having improved binding affinity to somatostatin receptors
US20070025910A1 (en) 2005-07-29 2007-02-01 Norenberg Jeffrey P Anticancer therapy
EP2750717B1 (en) * 2011-08-31 2019-03-27 Somscan ApS Pet tracer for imaging of neuroendocrine tumors

Also Published As

Publication number Publication date
ES2842998T3 (es) 2021-07-15
PL2750717T3 (pl) 2019-11-29
EP2750717B1 (en) 2019-03-27
EP2750717A1 (en) 2014-07-09
HUE052723T2 (hu) 2021-05-28
US11160888B2 (en) 2021-11-02
ES2732823T3 (es) 2019-11-26
EP3536346A1 (en) 2019-09-11
WO2013029616A1 (en) 2013-03-07
US10383961B2 (en) 2019-08-20
US20190321497A1 (en) 2019-10-24
US20190083664A1 (en) 2019-03-21
US10159759B2 (en) 2018-12-25
PL3536346T3 (pl) 2021-07-19
EP2750717A4 (en) 2015-03-04
HUE044625T2 (hu) 2019-11-28
US20140341807A1 (en) 2014-11-20
EP3536346B1 (en) 2020-10-28

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