DK3546462T3 - Nyt oxoisoquinolinderivat - Google Patents

Nyt oxoisoquinolinderivat Download PDF

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Publication number
DK3546462T3
DK3546462T3 DK17874560.0T DK17874560T DK3546462T3 DK 3546462 T3 DK3546462 T3 DK 3546462T3 DK 17874560 T DK17874560 T DK 17874560T DK 3546462 T3 DK3546462 T3 DK 3546462T3
Authority
DK
Denmark
Prior art keywords
new
oxoisoquinoline
derivative
oxoisoquinoline derivative
new oxoisoquinoline
Prior art date
Application number
DK17874560.0T
Other languages
English (en)
Inventor
Wataru Kawahata
Takao Kiyoi
Takayuki Irie
Tokiko ASAMI
Masaaki Sawa
Shigeki Kashimoto
Original Assignee
Carna Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Carna Biosciences Inc filed Critical Carna Biosciences Inc
Application granted granted Critical
Publication of DK3546462T3 publication Critical patent/DK3546462T3/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK17874560.0T 2016-11-25 2017-11-24 Nyt oxoisoquinolinderivat DK3546462T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2016229262 2016-11-25
JP2017191488 2017-09-29
PCT/JP2017/042172 WO2018097234A1 (ja) 2016-11-25 2017-11-24 新規オキソイソキノリン誘導体

Publications (1)

Publication Number Publication Date
DK3546462T3 true DK3546462T3 (da) 2024-03-04

Family

ID=62195030

Family Applications (1)

Application Number Title Priority Date Filing Date
DK17874560.0T DK3546462T3 (da) 2016-11-25 2017-11-24 Nyt oxoisoquinolinderivat

Country Status (12)

Country Link
US (1) US10793575B2 (da)
EP (1) EP3546462B1 (da)
JP (1) JP7015060B2 (da)
KR (1) KR102565546B1 (da)
CN (1) CN109963852B (da)
AU (1) AU2017364720B2 (da)
CA (1) CA3044933A1 (da)
DK (1) DK3546462T3 (da)
ES (1) ES2968023T3 (da)
FI (1) FI3546462T3 (da)
MX (1) MX389307B (da)
WO (1) WO2018097234A1 (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020119785A1 (zh) 2018-12-14 2020-06-18 正大天晴药业集团股份有限公司 一种Syk抑制剂的盐及其结晶型
US20230100235A1 (en) * 2020-02-05 2023-03-30 Carna Biosciences, Inc. Anticancer agent composition
US20230405006A1 (en) * 2020-11-13 2023-12-21 Carna Biosciences, Inc. Combination pharmaceutical composition and treatment method
US20240100172A1 (en) 2020-12-21 2024-03-28 Hangzhou Jijing Pharmaceutical Technology Limited Methods and compounds for targeted autophagy
KR20240157639A (ko) 2021-12-14 2024-11-01 크로스파이어 온콜로지 홀딩 비.브이. 거대고리 btk 억제제
CN116854709A (zh) * 2022-03-28 2023-10-10 药雅科技(上海)有限公司 Bruton′s酪氨酸激酶可逆抑制剂及其应用
JPWO2024134859A1 (da) 2022-12-23 2024-06-27
WO2024245578A1 (en) 2023-06-02 2024-12-05 Netherlands Translational Research Center Holding B.V. Therapeutic combinations of an irreversible btk inhibitor and a macrocyclic reversible btk inhibitor
WO2024245577A1 (en) 2023-06-02 2024-12-05 Netherlands Translational Research Center Holding B.V. Therapeutic combinations of an irreversible btk inhibitor and a reversible btk inhibitor
WO2024246287A1 (en) 2023-06-02 2024-12-05 Crossfire Oncology Holding B.V. Medical use of a macrocyclic reversible btk inhibitor
WO2024256574A1 (en) 2023-06-13 2024-12-19 Crossfire Oncology Holding B.V. Process for preparing macrocyclic btk inhibitors
WO2024256568A1 (en) 2023-06-13 2024-12-19 Crossfire Oncology Holding B.V. Salt and crystal forms of a macrocyclic btk inhibitor

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20140131955A (ko) 2012-03-09 2014-11-14 카나 바이오사이언스 인코포레이션 신규 트리아진 유도체
WO2013157021A1 (en) 2012-04-20 2013-10-24 Advinus Therapeutics Limited Bicyclic compounds, compositions and medicinal applications thereof
JP6182593B2 (ja) * 2012-04-20 2017-08-16 アドヴィーナス セラピューティクス リミテッド 置換ヘテロ二環化合物、組成物及び医薬並びにそれらの用途
CN104211703B (zh) * 2013-05-30 2018-04-03 南京勇山生物科技有限公司 一类作为布鲁顿激酶抑制剂的稠杂环化合物
DK3026050T3 (da) 2013-07-26 2019-02-18 Carna Biosciences Inc Nyt triazinderivat
EP3048102A1 (en) * 2013-09-20 2016-07-27 Carna Biosciences Inc. Novel triazine derivative

Also Published As

Publication number Publication date
MX389307B (es) 2025-03-20
AU2017364720B2 (en) 2021-09-23
AU2017364720A1 (en) 2019-06-20
BR112019010617A2 (pt) 2019-09-17
EP3546462A1 (en) 2019-10-02
EP3546462B1 (en) 2024-01-03
WO2018097234A1 (ja) 2018-05-31
RU2019119374A3 (da) 2020-12-25
RU2019119374A (ru) 2020-12-25
FI3546462T3 (fi) 2024-01-11
CN109963852B (zh) 2021-12-03
ES2968023T3 (es) 2024-05-06
KR20190104142A (ko) 2019-09-06
CA3044933A1 (en) 2018-05-31
KR102565546B1 (ko) 2023-08-10
US10793575B2 (en) 2020-10-06
JPWO2018097234A1 (ja) 2019-10-17
EP3546462A4 (en) 2020-07-01
JP7015060B2 (ja) 2022-02-02
CN109963852A (zh) 2019-07-02
MX2019006079A (es) 2019-11-12
US20190359616A1 (en) 2019-11-28

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