DK3555268T3 - Fremgangsmåder til produktion af fedtalkoholer og derivater deraf i gær - Google Patents

Fremgangsmåder til produktion af fedtalkoholer og derivater deraf i gær Download PDF

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Publication number
DK3555268T3
DK3555268T3 DK17825464.5T DK17825464T DK3555268T3 DK 3555268 T3 DK3555268 T3 DK 3555268T3 DK 17825464 T DK17825464 T DK 17825464T DK 3555268 T3 DK3555268 T3 DK 3555268T3
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Denmark
Prior art keywords
yeast
derivatives
processes
production
fatty alcohols
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DK17825464.5T
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English (en)
Inventor
Carina Holkenbrink
Marie Inger Dam
Christer Löfstedt
Irina Borodina
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Univ Danmarks Tekniske
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Publication of DK3555268T3 publication Critical patent/DK3555268T3/da

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0008Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0071Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/02Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y114/00Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
    • C12Y114/19Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water (1.14.19)
    • C12Y114/19001Stearoyl-CoA 9-desaturase (1.14.19.1), i.e. DELTA9-desaturase
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/582Recycling of unreacted starting or intermediate materials

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK17825464.5T 2016-12-16 2017-12-15 Fremgangsmåder til produktion af fedtalkoholer og derivater deraf i gær DK3555268T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16204769 2016-12-16
PCT/EP2017/083021 WO2018109163A1 (en) 2016-12-16 2017-12-15 Methods for producing fatty alcohols and derivatives thereof in yeast

Publications (1)

Publication Number Publication Date
DK3555268T3 true DK3555268T3 (da) 2021-08-30

Family

ID=57609699

Family Applications (1)

Application Number Title Priority Date Filing Date
DK17825464.5T DK3555268T3 (da) 2016-12-16 2017-12-15 Fremgangsmåder til produktion af fedtalkoholer og derivater deraf i gær

Country Status (9)

Country Link
US (1) US11345922B2 (da)
EP (2) EP3916087A1 (da)
CN (1) CN110300799B (da)
BR (1) BR112019012266B1 (da)
DE (1) DE17825464T1 (da)
DK (1) DK3555268T3 (da)
ES (1) ES2888232T3 (da)
HU (1) HUE055982T2 (da)
WO (1) WO2018109163A1 (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108697072A (zh) 2015-11-18 2018-10-23 普罗维维股份有限公司 用于产生昆虫信息素及相关化合物的微生物
WO2018213554A1 (en) 2017-05-17 2018-11-22 Provivi, Inc. Microorganisms for the production of insect pheromones and related compounds
US20230332096A1 (en) 2019-02-19 2023-10-19 Biophero Aps Methods and cell factories for producing insect pheromones
US20230332195A1 (en) * 2019-10-10 2023-10-19 River Stone Biotech Aps Genetically modified host cells producing benzylisoquinoline alkaloids
AU2020370542A1 (en) 2019-10-22 2022-04-28 FMC Agricultural Solutions A/S Improved methods for production, recovery and secretion of hydrophobic compounds in a fermentation
WO2021119548A1 (en) * 2019-12-11 2021-06-17 Provivi, Inc. Biosynthesis of insect pheromones and precursors thereof
CA3161539A1 (en) * 2019-12-20 2021-06-24 Irina BORODINA Yeast cells and methods for production of e8,e10-dodecadienyl coenzyme a, codlemone and derivatives thereof
CN114807240B (zh) * 2021-01-21 2024-02-06 深圳市第二人民医院(深圳市转化医学研究院) 一种连接有适配体的模板分子及其试剂盒
AU2022274152A1 (en) 2021-05-10 2023-11-23 FMC Agricultural Solutions A/S Improved methods and cells for increasing enzyme activity and production of insect pheromones
WO2023275374A1 (en) 2021-07-02 2023-01-05 Biophero Aps Methods and yeast cells for production of desaturated compounds
KR20240028439A (ko) 2021-07-02 2024-03-05 에프엠씨 애그리컬쳐럴 솔루션즈 에이/에스 탈포화 화합물의 생산을 위한 방법 및 효모 세포
WO2023012151A1 (en) 2021-08-06 2023-02-09 Biophero Aps Method for producing fatty aldehydes and derivatives thereof
US20230242944A1 (en) * 2022-01-31 2023-08-03 Isca Technologies, Inc. Methods for production of diatraea saccharalis pheromone precursors
US20230242945A1 (en) * 2022-01-31 2023-08-03 Isca Technologies, Inc. Methods for production of amyelois transitella pheromone precursor

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5876994A (en) 1995-11-16 1999-03-02 Cornell Research Foundation, Inc. Pheromone desaturases
US6593299B1 (en) 1999-04-21 2003-07-15 University Of Florida Research Foundation, Inc. Compositions and methods for controlling pests
DE10208812A1 (de) 2002-03-01 2003-09-11 Basf Plant Science Gmbh Verfahren zur Herstellung von ungesättigten Fettsäuren
ES2204328B1 (es) 2002-10-04 2005-09-01 Consejo Sup. De Invest. Cientificas Procedimiento de produccion de acidos grasos polinsaturados con levaduras por incorporacion de sustratos olefinicos o acetilenicos.
US20090117253A1 (en) 2007-10-03 2009-05-07 E. I. Du Pont De Nemours And Company Peroxisome biogenesis factor protein (pex) disruptions for altering polyunsaturated fatty acids and total lipid content in oleaginous eukaryotic organisms
PL2655612T3 (pl) 2010-12-23 2017-12-29 Shell Internationale Research Maatschappij B.V. Czynniki uszkadzające geny produkujące pochodne tłuszczowego acylo-coa
WO2012087958A2 (en) 2010-12-23 2012-06-28 Codexis, Inc. Yeast promoters
US20140357727A1 (en) 2011-12-20 2014-12-04 Codexis, Inc. Fatty alcohol forming acyl reductase (far) variants and methods of use
CN102795997A (zh) 2012-08-21 2012-11-28 昆明博鸿生物科技有限公司 小菜蛾性信息素化合物的合成方法
WO2015013674A2 (en) 2013-07-25 2015-01-29 The Regents Of The University Of California A yeast cell modified to overproduce fatty acid and fatty acid-derived compounds
WO2015057155A1 (en) 2013-10-18 2015-04-23 Biopetrolia Ab Engineering of hydrocarbon metabolism in yeast
WO2015171057A1 (en) 2014-05-06 2015-11-12 Per Hofvander Production of insect pheromone precursors in plants
ES2789823T3 (es) 2015-06-26 2020-10-26 Univ Danmarks Tekniske Procedimiento de producción de feromonas de polilla en levadura
CN108697072A (zh) * 2015-11-18 2018-10-23 普罗维维股份有限公司 用于产生昆虫信息素及相关化合物的微生物

Also Published As

Publication number Publication date
BR112019012266B1 (pt) 2022-08-30
CN110300799B (zh) 2024-01-19
ES2888232T3 (es) 2022-01-03
EP3555268A1 (en) 2019-10-23
BR112019012266A2 (pt) 2020-01-28
WO2018109163A1 (en) 2018-06-21
EP3916087A1 (en) 2021-12-01
DE17825464T1 (de) 2019-12-19
EP3555268B1 (en) 2021-05-26
HUE055982T2 (hu) 2022-01-28
CN110300799A (zh) 2019-10-01
US11345922B2 (en) 2022-05-31
US20190330646A1 (en) 2019-10-31

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