DK356885A - 3-aminomethyl-imidazo(1,2-a)pyridinderivater samt fremgangsmaade til fremstilling af og laegemiddel indeholdende saadanne forbindelser - Google Patents

3-aminomethyl-imidazo(1,2-a)pyridinderivater samt fremgangsmaade til fremstilling af og laegemiddel indeholdende saadanne forbindelser Download PDF

Info

Publication number: DK356885A
Authority: DK; Denmark
Prior art keywords: imidazo; aminomethyl; procedures; compounds; preparation
Prior art date: 1984-08-07

Application number

DK356885A

Other languages

English (en)

Other versions

DK163923C (da

DK356885D0 (da

DK163923B (da

Inventor

Pascal George

Claudie Giron

Original Assignee

Synthelabo

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-08-07

Filing date

1985-08-06

Publication date

1986-02-08

1985-08-06 Application filed by Synthelabo filed Critical Synthelabo

1985-08-06 Publication of DK356885D0 publication Critical patent/DK356885D0/da

1986-02-08 Publication of DK356885A publication Critical patent/DK356885A/da

1992-04-21 Publication of DK163923B publication Critical patent/DK163923B/da

1992-09-14 Application granted granted Critical

1992-09-14 Publication of DK163923C publication Critical patent/DK163923C/da

Links

150000001875 compounds Chemical class 0.000 title 1
HMKNKWJIRCGBBP-UHFFFAOYSA-N imidazo[1,2-a]pyridin-3-ylmethanamine Chemical class C1=CC=CN2C(CN)=CN=C21 HMKNKWJIRCGBBP-UHFFFAOYSA-N 0.000 title 1
238000000034 method Methods 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Neurosurgery (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Anesthesiology (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

DK356885A 1984-08-07 1985-08-06 2-phenyl-3-aminomethyl-imidazooe1,2-aaapyridinderivater og farmaceutisk praeparat indeholdende saadanne forbindelser DK163923C (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR8412447A FR2568880B1 (fr)	1984-08-07	1984-08-07	Derives d'acylaminomethyl-3 imidazo(1,2-a)pyridines, leur preparation et leur application en therapeutique
FR8412447		1984-08-07

Publications (4)

Publication Number	Publication Date
DK356885D0 DK356885D0 (da)	1985-08-06
DK356885A true DK356885A (da)	1986-02-08
DK163923B DK163923B (da)	1992-04-21
DK163923C DK163923C (da)	1992-09-14

Family

ID=9306856

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK356885A DK163923C (da)	1984-08-07	1985-08-06	2-phenyl-3-aminomethyl-imidazooe1,2-aaapyridinderivater og farmaceutisk praeparat indeholdende saadanne forbindelser

Country Status (23)

Country	Link
US (1)	US4650796A (da)
EP (1)	EP0172096B1 (da)
JP (1)	JPS6147485A (da)
KR (1)	KR910004450B1 (da)
AR (1)	AR241185A1 (da)
AT (1)	ATE40365T1 (da)
AU (1)	AU575190B2 (da)
CA (1)	CA1261830A (da)
CZ (1)	CZ357691A3 (da)
DE (1)	DE3567867D1 (da)
DK (1)	DK163923C (da)
ES (1)	ES8604592A1 (da)
FI (1)	FI80696C (da)
FR (1)	FR2568880B1 (da)
GR (1)	GR851928B (da)
HU (1)	HU193799B (da)
IE (1)	IE58347B1 (da)
IL (1)	IL76020A (da)
MX (1)	MX160845A (da)
NO (1)	NO162189C (da)
NZ (1)	NZ213013A (da)
PT (1)	PT80921B (da)
ZA (1)	ZA855939B (da)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2593180B1 (fr) *	1986-01-22	1990-10-26	Synthelabo	Derives d'acylaminomethyl-1 imidazo (1,2-a)quinoleines, leur preparation et leur application en therapeutique
FR2593818B1 (fr) *	1986-02-05	1988-04-29	Synthelabo	Derives d'acylaminomethyl-3 imidazo(1,2-a)pyridine, leur preparation et leur application en therapeutique
ES2032455T3 (es) *	1986-01-22	1993-02-16	Synthelabo	Procedimiento para preparar derivados de 3-acilaminometil-imidazo (-1,2-a)piridinas.
US4990506A (en) *	1986-02-05	1991-02-05	Synthelabo	3-(acylaminomethyl)imidazo[1,2-a]pyridine derivatives and their application in therapy
FR2606409B1 (fr) *	1986-11-07	1989-05-05	Synthelabo	Derives d'imidazopyridine, leur preparation et leur application en therapeutique
DE3865073D1 (de) *	1987-03-27	1991-10-31	Synthelabo	Imidazopyridinderivate, ihre herstellung und therapeutische verwendung.
FR2615513B1 (fr) *	1987-05-21	1989-07-13	Synthelabo	Derives d'acylaminomethyl-3 tetrahydro-5,6,7,8 imidazo(1,2-a)pyridines, leur preparation et leur application en therapeutique
FR2654933B1 (fr) *	1989-11-30	1994-06-10	Synthelabo	Utilisation d'une imidazopyridine pour la fabrication de medicaments anesthesiques.
US5716964A (en) *	1989-12-04	1998-02-10	G.D. Searle & Co.	Tetrazolyl substituted imidazo 1,2-a!pyridinylalkyl compounds for treatment of neurotoxic injury
KR910011852A (ko) *	1989-12-04	1991-08-07	폴 디. 매튜카이티스	신경독 장해 치료용 이미다조[1,2-a]피리디닐알킬 화합물
IE904346A1 (en) *	1989-12-04	1991-06-05	Searle & Co	IMIDAZO[1,2-a]PYRIDINYLALKYL COMPOUNDS FOR TREATMENT OF¹NEUROTOXIC INJURY
US5464843A (en) *	1992-06-23	1995-11-07	G.D. Searle & Co.	Imidazo[1,2-a]pyridinyldiacid compounds for cognitive enhancement and for treatment of cognitive disorders and neutrotoxic injury
AUPP278498A0 (en) *	1998-04-03	1998-04-30	Australian Nuclear Science & Technology Organisation	Peripheral benzodiazepine receptor binding agents
DE10019714A1 (de) *	2000-04-20	2002-01-10	Gruenenthal Gmbh	Salze von bicyclischen, N-acylierten Imidazo-3-aminen und Imidazo-5-aminen
AU2001270297A1 (en)	2000-06-30	2002-01-14	Neurogen Corporation	2-phenylimidazo(1,2-a)pyridine derivatives: a new class of gaba brain receptor ligands
US6596731B2 (en)	2001-03-27	2003-07-22	Hoffmann-La Roche Inc.	Substituted imidazo[1,2-A] pyridine derivatives
DE10247269A1 (de)	2002-10-10	2004-04-22	Grünenthal GmbH	Substituierte C-Imidazo[1,2-a]pyridin-3-yl-methylamine
US7148353B2 (en) *	2003-10-28	2006-12-12	Sepracor Inc.	Imidazo[1,2-a] pyridine anxiolytics
WO2005081749A2 (en) *	2004-01-23	2005-09-09	Avanir Pharmaceuticals, Inc.	Neutralizing human antibodies to anthraxtoxin
FR2874611B1 (fr) *	2004-08-31	2006-11-17	Servier Lab	Nouveaux derives d'imidazopyridine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
CN101065377B (zh) *	2004-11-11	2011-07-27	菲尔若国际公司	咪唑并[1,2-a]吡啶化合物、组合物、与其有关的应用和方法
JP2008542323A (ja)	2005-06-01	2008-11-27	ユセベファルマソシエテアノニム	２−オキソ−１−ピロリジン誘導体、その製造方法及びその使用
WO2008132142A2 (en) *	2007-04-27	2008-11-06	Ucb Pharma S.A.	New heterocyclic derivatives useful for the treatment of cns disorders
EP2300470A2 (en) *	2008-05-19	2011-03-30	Sepracor Inc.	Imidazo[1,2-a]pyridine compounds as gaba-a receptor modulators
DK2376490T3 (da) *	2008-12-04	2013-04-15	Proximagen Ltd	Imidazopyridinforbindelser
WO2014187922A1 (en)	2013-05-24	2014-11-27	Iomet Pharma Ltd.	Slc2a transporter inhibitors
US12282014B2 (en)	2015-11-19	2025-04-22	Dana-Farber Cancer Institute, Inc.	Methods of identifying compounds that interfere with ERG-driven misguidance of BAF complexes in TMPRSS2-ERG driven prostate cancers
US11497752B2 (en)	2018-01-30	2022-11-15	Foghorn Therapeutics Inc.	Compounds and uses thereof
WO2020081588A1 (en)	2018-10-17	2020-04-23	Dana-Farber Cancer Institute, Inc.	Swi/snf family chromatin remodeling complexes and uses thereof
AU2019416589B2 (en) *	2018-12-29	2023-04-06	Wuhan Ll Science And Technology Development Co., Ltd.	Heterocyclic compound intermediate, preparation method therefor and application thereof
WO2020160196A1 (en)	2019-01-29	2020-08-06	Foghorn Therapeutics Inc.	Compounds and uses thereof
WO2020160100A1 (en)	2019-01-29	2020-08-06	Foghorn Therapeutics Inc.	Compounds and uses thereof
EP4096668A4 (en) *	2020-01-29	2024-02-28	Foghorn Therapeutics Inc.	COMPOUNDS AND USES THEREOF
BR112022015004A2 (pt)	2020-01-29	2022-09-20	Foghorn Therapeutics Inc	Composto, composição farmacêutica, métodos para diminuir a atividade de um complexo baf, induzir apoptose, reduzir o crescimento tumoral, suprimir a progressão e a colonização metastática do câncer e reduzir o nível e/ou a atividade de brg1 e/ou brm em um câncer e métodos de tratamento e de inibição de brm e brg1
US12383555B2 (en)	2020-05-20	2025-08-12	Foghorn Therapeutics Inc.	Methods of treating cancers
JP2024509268A (ja)	2021-03-09	2024-02-29	フォグホーンセラピューティクスインコーポレイテッド	結晶形、それらを含有する組成物、及びそれらの使用方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB991589A (en) *	1963-04-30	1965-05-12	Selvi & C Lab Bioterapico	Novel [1,2-ª‡]imidazopyridines and a process for the manufacture thereof
GB1076089A (en) *	1965-11-09	1967-07-19	Selvi & C Lab Bioterapico	New derivatives of imidazo [1,2-a]-pyridine and a process for the manufacture thereof

1984
- 1984-08-07 FR FR8412447A patent/FR2568880B1/fr not_active Expired
1985
- 1985-07-30 DE DE8585401554T patent/DE3567867D1/de not_active Expired
- 1985-07-30 EP EP85401554A patent/EP0172096B1/fr not_active Expired
- 1985-07-30 AT AT85401554T patent/ATE40365T1/de not_active IP Right Cessation
- 1985-08-06 NZ NZ213013A patent/NZ213013A/en unknown
- 1985-08-06 ES ES545928A patent/ES8604592A1/es not_active Expired
- 1985-08-06 PT PT80921A patent/PT80921B/pt not_active IP Right Cessation
- 1985-08-06 GR GR851928A patent/GR851928B/el unknown
- 1985-08-06 DK DK356885A patent/DK163923C/da not_active IP Right Cessation
- 1985-08-06 AU AU45809/85A patent/AU575190B2/en not_active Ceased
- 1985-08-06 HU HU852991A patent/HU193799B/hu not_active IP Right Cessation
- 1985-08-06 CA CA000488165A patent/CA1261830A/en not_active Expired
- 1985-08-06 FI FI853026A patent/FI80696C/fi not_active IP Right Cessation
- 1985-08-06 NO NO853100A patent/NO162189C/no unknown
- 1985-08-06 IL IL76020A patent/IL76020A/xx not_active IP Right Cessation
- 1985-08-06 MX MX206217A patent/MX160845A/es unknown
- 1985-08-06 KR KR1019850005660A patent/KR910004450B1/ko not_active Expired
- 1985-08-06 ZA ZA855939A patent/ZA855939B/xx unknown
- 1985-08-06 IE IE193785A patent/IE58347B1/en not_active IP Right Cessation
- 1985-08-06 AR AR85301203A patent/AR241185A1/es active
- 1985-08-06 JP JP60173977A patent/JPS6147485A/ja active Granted
1986
- 1986-02-07 US US06/826,966 patent/US4650796A/en not_active Expired - Lifetime
1991
- 1991-11-25 CZ CS913576A patent/CZ357691A3/cs unknown

Also Published As

Publication number	Publication date
DK163923C (da)	1992-09-14
CZ357691A3 (en)	1993-06-16
FR2568880B1 (fr)	1986-12-12
NO853100L (no)	1986-02-10
ZA855939B (en)	1986-03-26
FI80696C (fi)	1990-07-10
ES545928A0 (es)	1986-02-01
PT80921A (fr)	1985-09-01
ES8604592A1 (es)	1986-02-01
EP0172096A1 (fr)	1986-02-19
PT80921B (pt)	1987-12-30
DK356885D0 (da)	1985-08-06
DK163923B (da)	1992-04-21
HUT38637A (en)	1986-06-30
IE58347B1 (en)	1993-09-08
MX160845A (es)	1990-05-31
JPH0523267B2 (da)	1993-04-02
NO162189C (no)	1989-11-29
AR241185A1 (es)	1992-01-31
US4650796A (en)	1987-03-17
KR860001809A (ko)	1986-03-22
IL76020A0 (en)	1985-12-31
AU575190B2 (en)	1988-07-21
HU193799B (en)	1987-11-30
NZ213013A (en)	1988-05-30
IL76020A (en)	1989-01-31
EP0172096B1 (fr)	1989-01-25
JPS6147485A (ja)	1986-03-07
NO162189B (no)	1989-08-14
GR851928B (da)	1985-12-09
CA1261830A (en)	1989-09-26
FI853026A0 (fi)	1985-08-06
FI853026L (fi)	1986-02-08
FI80696B (fi)	1990-03-30
AU4580985A (en)	1986-02-13
IE851937L (en)	1986-02-07
DE3567867D1 (en)	1989-03-02
KR910004450B1 (ko)	1991-06-29
FR2568880A1 (fr)	1986-02-14
ATE40365T1 (de)	1989-02-15

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