DK35889A - Vitamin d3 derivater og farmaceutiske praeparater indeholdende disse forbindelser - Google Patents

Vitamin d3 derivater og farmaceutiske praeparater indeholdende disse forbindelser

Info

Publication number: DK35889A
Authority: DK; Denmark
Prior art keywords: derivatives; vitamin; compounds; pharmaceutical preparations; preparations containing
Prior art date: 1985-01-17

Application number

DK035889A

Other languages

English (en)

Other versions

DK35889D0 (da

DK159273B (da

DK159273C (da

Inventor

Hector F Deluca

Nobuo Ikekawa

Yoko Tanaka

Heinrich K Schnoes

Voula Ostrem

Original Assignee

Wisconsin Alumni Res Found

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-01-17

Filing date

1989-01-27

Publication date

1989-01-27

1985-05-30 Priority claimed from US06/739,332 external-priority patent/US4717721A/en

1989-01-27 Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found

1989-01-27 Publication of DK35889D0 publication Critical patent/DK35889D0/da

1989-01-27 Publication of DK35889A publication Critical patent/DK35889A/da

1990-09-24 Publication of DK159273B publication Critical patent/DK159273B/da

1991-02-18 Application granted granted Critical

1991-02-18 Publication of DK159273C publication Critical patent/DK159273C/da

Links

150000001875 compounds Chemical class 0.000 title 1
239000000825 pharmaceutical preparation Substances 0.000 title 1
150000003704 vitamin D3 derivatives Chemical class 0.000 title 1
125000002252 acyl group Chemical group 0.000 abstract 2
125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 2
-1 and R1- R3 are H Chemical group 0.000 abstract 1
239000000543 intermediate Substances 0.000 abstract 1
125000004184 methoxymethyl group Chemical group [H]C([H])([H])OC([H])([H])* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Endocrinology (AREA)
Rheumatology (AREA)
Nutrition Science (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

DK035889A 1985-01-17 1989-01-27 26-homocholesta-5,7-dienforbindelser, der kan anvendes som mellemprodukter til brug ved fremstillingen af 26-homovitamin d3 derivater DK159273C (da)

Applications Claiming Priority (6)

Application Number	Priority Date	Filing Date	Title
US69215185A	1985-01-17	1985-01-17
US69215185		1985-01-17
US06/739,332 US4717721A (en)	1985-05-30	1985-05-30	Sidechain homo-vitamin D compounds with preferential anti-cancer activity
US73933285		1985-05-30
PCT/US1986/000093 WO1986004333A1 (en)	1985-01-17	1986-01-15	Vitamin d derivatives and methods for preparing same
US8600093		1986-01-15

Publications (4)

Publication Number	Publication Date
DK35889D0 DK35889D0 (da)	1989-01-27
DK35889A true DK35889A (da)	1989-01-27
DK159273B DK159273B (da)	1990-09-24
DK159273C DK159273C (da)	1991-02-18

Family

ID=27104918

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
DK443186A DK157007C (da)	1985-01-17	1986-09-16	Vitamin d3 derivater, farmaceutiske praeparater indeholdende disse forbindelser, samt anvendelse af disse forbindelser til fremstilling af farmaceutiske praeparater til behandling af neoplastiske sygdomme eller til induktion af differentiering i maligne celler
DK035889A DK159273C (da)	1985-01-17	1989-01-27	26-homocholesta-5,7-dienforbindelser, der kan anvendes som mellemprodukter til brug ved fremstillingen af 26-homovitamin d3 derivater
DK056490A DK162394C (da)	1985-01-17	1990-03-05	26-homocholesta-5-en forbindelse, der kan anvendes som mellemprodukt til brug ved fremstillingen af 26-homovitamin d3 derivater

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
DK443186A DK157007C (da)	1985-01-17	1986-09-16	Vitamin d3 derivater, farmaceutiske praeparater indeholdende disse forbindelser, samt anvendelse af disse forbindelser til fremstilling af farmaceutiske praeparater til behandling af neoplastiske sygdomme eller til induktion af differentiering i maligne celler

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
DK056490A DK162394C (da)	1985-01-17	1990-03-05	26-homocholesta-5-en forbindelse, der kan anvendes som mellemprodukt til brug ved fremstillingen af 26-homovitamin d3 derivater

Country Status (7)

Country	Link
EP (1)	EP0211863B1 (da)
JP (3)	JPH0678354B2 (da)
KR (1)	KR910004337B1 (da)
AU (1)	AU594662B2 (da)
DE (1)	DE3687377T2 (da)
DK (3)	DK157007C (da)
WO (1)	WO1986004333A1 (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4927815A (en) *	1988-04-29	1990-05-22	Wisconsin Alumni Research Foundation	Compounds effective in inducing cell differentiation and process for preparing same
KR940003360B1 (ko) *	1988-04-29	1994-04-21	위스콘신 알럼나이 리써취 파운데이션	불포화 측쇄를 갖는 1α-히드록시비타민 D동족체
GB2229921B (en) *	1989-04-05	1992-12-16	Chugai Pharmaceutical Co Ltd	Treatment for hyperparathyroidism with use of vitamin d derivatives
US5260290A (en) *	1990-02-14	1993-11-09	Wisconsin Alumni Research Foundation	Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives
US5030772A (en) *	1990-02-14	1991-07-09	Deluca Hector F	Process for preparing vitamin D2 compounds and the corresponding 1 α-hydroxylated derivatives

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3880894A (en) *	1974-05-24	1975-04-29	Wisconsin Alumni Res Found	1,25-Dihydroxyergocalciferol
US4226770A (en) *	1978-02-10	1980-10-07	Kaiser Emil T	Synthesis of steroids
US4163744A (en)	1978-02-10	1979-08-07	Kaiser Emil T	Synthesis of steroids
US4508651A (en) *	1983-03-21	1985-04-02	Hoffmann-La Roche Inc.	Synthesis of 1α,25-dihydroxyergocalciferol
WO1984004527A1 (en) *	1983-05-09	1984-11-22	Wisconsin Alumni Res Found	PROCESS FOR THE PREPARATION OF 1alpha,25-DIHYDROXYLATED VITAMIN D2 AND RELATED COMPOUNDS
NL8520009A (nl) *	1984-01-30	1985-12-02	Wisconsin Alumni Res Found	1alfa.25-dihydroxy-22z-dehydrovitamine d verbinding.

1986
- 1986-01-15 EP EP86900954A patent/EP0211863B1/en not_active Expired - Lifetime
- 1986-01-15 AU AU53597/86A patent/AU594662B2/en not_active Ceased
- 1986-01-15 KR KR1019860700644A patent/KR910004337B1/ko not_active Expired
- 1986-01-15 DE DE8686900954T patent/DE3687377T2/de not_active Expired - Fee Related
- 1986-01-15 WO PCT/US1986/000093 patent/WO1986004333A1/en not_active Ceased
- 1986-09-16 DK DK443186A patent/DK157007C/da not_active IP Right Cessation
1989
- 1989-01-27 DK DK035889A patent/DK159273C/da not_active IP Right Cessation
1990
- 1990-03-05 DK DK056490A patent/DK162394C/da not_active IP Right Cessation
1992
- 1992-03-10 JP JP4086420A patent/JPH0678354B2/ja not_active Expired - Lifetime
- 1992-03-10 JP JP4086421A patent/JPH0635474B2/ja not_active Expired - Lifetime
- 1992-03-10 JP JP4086422A patent/JPH0737391B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
KR870700071A (ko)	1987-02-28
DK35889D0 (da)	1989-01-27
JPH05132499A (ja)	1993-05-28
EP0211863A4 (en)	1987-03-16
AU5359786A (en)	1986-08-13
EP0211863A1 (en)	1987-03-04
WO1986004333A1 (en)	1986-07-31
DK157007C (da)	1990-03-19
JPH0635474B2 (ja)	1994-05-11
DK159273B (da)	1990-09-24
DK162394B (da)	1991-10-21
EP0211863B1 (en)	1992-12-30
DK56490D0 (da)	1990-03-05
DE3687377T2 (de)	1993-04-29
DK159273C (da)	1991-02-18
AU594662B2 (en)	1990-03-15
JPH06128160A (ja)	1994-05-10
JPH0737391B2 (ja)	1995-04-26
DK56490A (da)	1990-03-05
DK443186A (da)	1986-09-16
DK162394C (da)	1992-03-09
DK443186D0 (da)	1986-09-16
JPH0678354B2 (ja)	1994-10-05
DE3687377D1 (de)	1993-02-11
DK157007B (da)	1989-10-30
JPH0649092A (ja)	1994-02-22
KR910004337B1 (ko)	1991-06-26

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Legal Events

Date	Code	Title	Description
1999-05-03	PBP	Patent lapsed