DK3615515T3 - Propionsyrederivater og fremgangsmåder til anvendelse deraf - Google Patents
Propionsyrederivater og fremgangsmåder til anvendelse deraf Download PDFInfo
- Publication number
- DK3615515T3 DK3615515T3 DK18799302.7T DK18799302T DK3615515T3 DK 3615515 T3 DK3615515 T3 DK 3615515T3 DK 18799302 T DK18799302 T DK 18799302T DK 3615515 T3 DK3615515 T3 DK 3615515T3
- Authority
- DK
- Denmark
- Prior art keywords
- methods
- propionic acid
- acid derivatives
- derivatives
- propionic
- Prior art date
Links
- 229940111131 antiinflammatory and antirheumatic product propionic acid derivative Drugs 0.000 title 1
- 150000005599 propionic acid derivatives Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15/497,416 US10246451B2 (en) | 2017-04-26 | 2017-04-26 | Propionic acid derivatives and methods of use thereof |
| PCT/US2018/039291 WO2018209363A2 (en) | 2017-04-26 | 2018-06-25 | Propionic acid derivatives and methods of use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3615515T3 true DK3615515T3 (da) | 2024-11-11 |
Family
ID=63916458
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK18799302.7T DK3615515T3 (da) | 2017-04-26 | 2018-06-25 | Propionsyrederivater og fremgangsmåder til anvendelse deraf |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US10246451B2 (da) |
| EP (1) | EP3615515B1 (da) |
| CN (1) | CN110914241B (da) |
| AU (1) | AU2018266966B2 (da) |
| CA (1) | CA3061363A1 (da) |
| DK (1) | DK3615515T3 (da) |
| WO (1) | WO2018209363A2 (da) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10246451B2 (en) * | 2017-04-26 | 2019-04-02 | Aviara Pharmaceuticals, Inc. | Propionic acid derivatives and methods of use thereof |
| EP3773573B1 (en) | 2018-04-12 | 2026-03-18 | Morphic Therapeutic, Inc. | Antagonists of human integrin (alpha4)(beta7) |
| FI3873884T3 (fi) | 2018-10-30 | 2025-02-24 | Gilead Sciences Inc | 3-(kinolin-8-yyli)-1,4-dihydropyrido[3,4-d]pyrimidiini-2,4-dionijohdannaisia alfa-4-beta-7-integriinin estäjinä tulehdussairauksien hoidossa |
| JP7189368B2 (ja) | 2018-10-30 | 2022-12-13 | ギリアード サイエンシーズ， インコーポレイテッド | アルファ４ベータ７インテグリンの阻害のための化合物 |
| ES3013256T3 (en) | 2018-10-30 | 2025-04-11 | Gilead Sciences Inc | Imidazo[1,2-a]pyridine derivatives as alpha4beta7 integrin inhibitors for the treatment of inflammatory diseases |
| EP3873605B1 (en) | 2018-10-30 | 2024-10-23 | Gilead Sciences, Inc. | Compounds for inhibition of alpha4beta7 integrin |
| WO2021030438A1 (en) | 2019-08-14 | 2021-02-18 | Gilead Sciences, Inc. | Compounds for inhibition of alpha 4 beta 7 integrin |
| TWI775182B (zh) | 2019-10-16 | 2022-08-21 | 美商莫菲克醫療股份有限公司 | 抑制人類整合素αβ |
| EP4452248A4 (en) * | 2021-12-20 | 2025-12-10 | Nimml Inst | IMMUNOREGULATORY COMPOUNDS |
| KR20250061759A (ko) * | 2022-09-09 | 2025-05-08 | 시젱 하이스코 파마수티칼 씨오., 엘티디. | 프로피온산 유도체 및 이의 의약에서의 응용 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6972296B2 (en) * | 1999-05-07 | 2005-12-06 | Encysive Pharmaceuticals Inc. | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors |
| ATE383153T1 (de) * | 1999-05-07 | 2008-01-15 | Encysive Pharmaceuticals Inc | Carbonsäurederivate die die bindung von integrinen an ihre rezeptoren hemmen |
| US10246451B2 (en) * | 2017-04-26 | 2019-04-02 | Aviara Pharmaceuticals, Inc. | Propionic acid derivatives and methods of use thereof |
-
2017
- 2017-04-26 US US15/497,416 patent/US10246451B2/en active Active
-
2018
- 2018-06-25 EP EP18799302.7A patent/EP3615515B1/en active Active
- 2018-06-25 WO PCT/US2018/039291 patent/WO2018209363A2/en not_active Ceased
- 2018-06-25 DK DK18799302.7T patent/DK3615515T3/da active
- 2018-06-25 CN CN201880042064.4A patent/CN110914241B/zh active Active
- 2018-06-25 AU AU2018266966A patent/AU2018266966B2/en not_active Ceased
- 2018-06-25 CA CA3061363A patent/CA3061363A1/en active Pending
-
2019
- 2019-04-01 US US16/372,189 patent/US10494367B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN110914241B (zh) | 2023-11-14 |
| EP3615515A2 (en) | 2020-03-04 |
| EP3615515B1 (en) | 2024-09-25 |
| US20180312498A1 (en) | 2018-11-01 |
| WO2018209363A3 (en) | 2019-01-03 |
| US10494367B2 (en) | 2019-12-03 |
| AU2018266966A1 (en) | 2019-12-19 |
| WO2018209363A2 (en) | 2018-11-15 |
| CA3061363A1 (en) | 2018-11-15 |
| AU2018266966B2 (en) | 2022-09-01 |
| US20190225602A1 (en) | 2019-07-25 |
| EP3615515A4 (en) | 2020-09-02 |
| US10246451B2 (en) | 2019-04-02 |
| CN110914241A (zh) | 2020-03-24 |
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