DK3625231T3 - Derivatives of resiquimod - Google Patents
Derivatives of resiquimod Download PDFInfo
- Publication number
- DK3625231T3 DK3625231T3 DK18729301.4T DK18729301T DK3625231T3 DK 3625231 T3 DK3625231 T3 DK 3625231T3 DK 18729301 T DK18729301 T DK 18729301T DK 3625231 T3 DK3625231 T3 DK 3625231T3
- Authority
- DK
- Denmark
- Prior art keywords
- resiquimod
- derivatives
- Prior art date
Links
- BXNMTOQRYBFHNZ-UHFFFAOYSA-N resiquimod Chemical class C1=CC=CC2=C(N(C(COCC)=N3)CC(C)(C)O)C3=C(N)N=C21 BXNMTOQRYBFHNZ-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/05—Isotopically modified compounds, e.g. labelled
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Virology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Pulmonology (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762508722P | 2017-05-19 | 2017-05-19 | |
| PCT/US2018/033493 WO2018213769A1 (en) | 2017-05-19 | 2018-05-18 | Derivatives of resiquimod |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3625231T3 true DK3625231T3 (da) | 2022-10-31 |
Family
ID=62528901
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK18729301.4T DK3625231T3 (da) | 2017-05-19 | 2018-05-18 | Derivatives of resiquimod |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US11274099B2 (da) |
| EP (1) | EP3625231B1 (da) |
| JP (1) | JP7228574B2 (da) |
| KR (1) | KR102650538B1 (da) |
| CN (2) | CN116854686A (da) |
| AU (1) | AU2018270266B2 (da) |
| BR (1) | BR112019024177A2 (da) |
| CA (1) | CA3063953A1 (da) |
| DK (1) | DK3625231T3 (da) |
| ES (1) | ES2928723T3 (da) |
| IL (1) | IL270703B2 (da) |
| MX (1) | MX2019013769A (da) |
| PH (1) | PH12019502544B1 (da) |
| WO (1) | WO2018213769A1 (da) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112019024177A2 (pt) * | 2017-05-19 | 2020-06-02 | Superb Wisdom Limited | Derivados de resiquimode |
| US20240382469A1 (en) * | 2021-09-17 | 2024-11-21 | Birdie Biopharmaceuticals, Inc. | Combination therapy with deuterated imidazoquinolines |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL73534A (en) * | 1983-11-18 | 1990-12-23 | Riker Laboratories Inc | 1h-imidazo(4,5-c)quinoline-4-amines,their preparation and pharmaceutical compositions containing certain such compounds |
| US5389640A (en) | 1991-03-01 | 1995-02-14 | Minnesota Mining And Manufacturing Company | 1-substituted, 2-substituted 1H-imidazo[4,5-c]quinolin-4-amines |
| CA2289219C (en) * | 1991-03-01 | 2003-05-20 | Minnesota Mining And Manufacturing Company | 1-substituted, 2-substituted 1h-imidazo[4,5-c]quinolin-4-amines |
| KR100235389B1 (ko) * | 1991-03-01 | 1999-12-15 | 스프레이그 로버트 월터 | 1-치환된, 2-치환된 1H-이미다조[4,5-c]퀴놀린-4-아민 |
| US6221335B1 (en) * | 1994-03-25 | 2001-04-24 | Isotechnika, Inc. | Method of using deuterated calcium channel blockers |
| KR100518903B1 (ko) | 1996-10-25 | 2005-10-06 | 미네소타 마이닝 앤드 매뉴팩춰링 캄파니 | Ｔｈ2 매개 질병 및 관련 질병의 치료용 면역 반응 조절 화합물 |
| TR200101943T2 (tr) | 1999-01-08 | 2002-04-22 | 3M Innovative Properties Company | Bir immun cevap modifayeri ile mukoza ile ilgili durumların tedavisine yönelik formülasyonlar ve metodlar. |
| US6486168B1 (en) | 1999-01-08 | 2002-11-26 | 3M Innovative Properties Company | Formulations and methods for treatment of mucosal associated conditions with an immune response modifier |
| GB9925962D0 (en) | 1999-11-02 | 1999-12-29 | Novartis Ag | Organic compounds |
| HU229938B1 (en) | 2001-05-03 | 2015-01-28 | Hoffmann La Roche | Pharmaceutical dosage form of amorphous nelfinavir mesylate |
| CA2446904A1 (en) | 2001-05-24 | 2003-04-03 | Alexza Pharmaceuticals, Inc. | Delivery of drug esters through an inhalation route |
| US20060183767A1 (en) | 2003-01-06 | 2006-08-17 | Eugene Mandrea | Methods of stimulating immune response in certain individuals |
| CA2540541C (en) | 2003-10-03 | 2012-03-27 | 3M Innovative Properties Company | Alkoxy substituted imidazoquinolines |
| WO2006115509A2 (en) | 2004-06-24 | 2006-11-02 | Novartis Vaccines And Diagnostics Inc. | Small molecule immunopotentiators and assays for their detection |
| US20060094744A1 (en) | 2004-09-29 | 2006-05-04 | Maryanoff Cynthia A | Pharmaceutical dosage forms of stable amorphous rapamycin like compounds |
| US20160206715A1 (en) * | 2013-03-15 | 2016-07-21 | Bullet Biotechnology, Inc. | Specific multivalent virus-like particle vaccines and uses thereof |
| US20180222982A1 (en) * | 2015-07-29 | 2018-08-09 | Novartis Ag | Combination therapies comprising antibody molecules to pd-1 |
| JP7100578B2 (ja) * | 2015-11-05 | 2022-07-13 | ザ ジェネラル ホスピタル コーポレイション | 腫瘍内免疫応答を増強することによってがんを治療するための方法 |
| BR112019024177A2 (pt) * | 2017-05-19 | 2020-06-02 | Superb Wisdom Limited | Derivados de resiquimode |
-
2018
- 2018-05-18 BR BR112019024177-9A patent/BR112019024177A2/pt not_active Application Discontinuation
- 2018-05-18 WO PCT/US2018/033493 patent/WO2018213769A1/en not_active Ceased
- 2018-05-18 CN CN202310632172.XA patent/CN116854686A/zh active Pending
- 2018-05-18 MX MX2019013769A patent/MX2019013769A/es unknown
- 2018-05-18 EP EP18729301.4A patent/EP3625231B1/en active Active
- 2018-05-18 JP JP2020514152A patent/JP7228574B2/ja active Active
- 2018-05-18 KR KR1020197037270A patent/KR102650538B1/ko active Active
- 2018-05-18 US US16/612,216 patent/US11274099B2/en active Active
- 2018-05-18 ES ES18729301T patent/ES2928723T3/es active Active
- 2018-05-18 CA CA3063953A patent/CA3063953A1/en active Pending
- 2018-05-18 CN CN201880044288.9A patent/CN111094282B/zh active Active
- 2018-05-18 AU AU2018270266A patent/AU2018270266B2/en not_active Ceased
- 2018-05-18 DK DK18729301.4T patent/DK3625231T3/da active
- 2018-05-18 PH PH1/2019/502544A patent/PH12019502544B1/en unknown
-
2019
- 2019-11-17 IL IL270703A patent/IL270703B2/en unknown
-
2022
- 2022-02-04 US US17/665,104 patent/US12077535B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| BR112019024177A2 (pt) | 2020-06-02 |
| MX2019013769A (es) | 2020-07-20 |
| US11274099B2 (en) | 2022-03-15 |
| EP3625231B1 (en) | 2022-07-20 |
| PH12019502544B1 (en) | 2023-07-26 |
| RU2019141473A3 (da) | 2021-09-17 |
| AU2018270266A1 (en) | 2020-01-16 |
| AU2018270266B2 (en) | 2022-06-30 |
| WO2018213769A1 (en) | 2018-11-22 |
| CN116854686A (zh) | 2023-10-10 |
| KR20200038889A (ko) | 2020-04-14 |
| US20200207757A1 (en) | 2020-07-02 |
| JP7228574B2 (ja) | 2023-02-24 |
| ES2928723T3 (es) | 2022-11-22 |
| RU2019141473A (ru) | 2021-06-21 |
| CN111094282A (zh) | 2020-05-01 |
| US12077535B2 (en) | 2024-09-03 |
| PH12019502544A1 (en) | 2020-07-13 |
| US20230002370A1 (en) | 2023-01-05 |
| CA3063953A1 (en) | 2018-11-22 |
| CN111094282B (zh) | 2023-06-16 |
| IL270703B2 (en) | 2023-07-01 |
| IL270703A (en) | 2020-01-30 |
| KR102650538B1 (ko) | 2024-03-21 |
| IL270703B1 (en) | 2023-03-01 |
| EP3625231A1 (en) | 2020-03-25 |
| JP2020520993A (ja) | 2020-07-16 |
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