DK3639191T4 - Fremgangsmåde til træning af en deep learning-model for at opnå histopatologisk information fra billeder - Google Patents

Fremgangsmåde til træning af en deep learning-model for at opnå histopatologisk information fra billeder Download PDF

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DK3639191T4
DK3639191T4 DK18729159.6T DK18729159T DK3639191T4 DK 3639191 T4 DK3639191 T4 DK 3639191T4 DK 18729159 T DK18729159 T DK 18729159T DK 3639191 T4 DK3639191 T4 DK 3639191T4
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training
approach
images
learning model
deep learning
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DK18729159.6T
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DK3639191T3 (da
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Jeppe Thagaard
Thomas Ebstrup
Michael Grunkin
Johan Doré Hansen
Michael Friis Lippert
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Visiopharm As
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    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V10/00—Arrangements for image or video recognition or understanding
    • G06V10/70—Arrangements for image or video recognition or understanding using pattern recognition or machine learning
    • G06V10/77—Processing image or video features in feature spaces; using data integration or data reduction, e.g. principal component analysis [PCA] or independent component analysis [ICA] or self-organising maps [SOM]; Blind source separation
    • G06V10/774—Generating sets of training patterns; Bootstrap methods, e.g. bagging or boosting
    • G06V10/7753—Incorporation of unlabelled data, e.g. multiple instance learning [MIL]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/0002—Inspection of images, e.g. flaw detection
    • G06T7/0012—Biomedical image inspection
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/30—Determination of transform parameters for the alignment of images, i.e. image registration
    • G06T7/33—Determination of transform parameters for the alignment of images, i.e. image registration using feature-based methods
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V20/00—Scenes; Scene-specific elements
    • G06V20/60—Type of objects
    • G06V20/69—Microscopic objects, e.g. biological cells or cellular parts
    • G06V20/698—Matching; Classification
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/20—Special algorithmic details
    • G06T2207/20081—Training; Learning
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/30—Subject of image; Context of image processing
    • G06T2207/30004—Biomedical image processing
    • G06T2207/30024—Cell structures in vitro; Tissue sections in vitro
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V2201/00—Indexing scheme relating to image or video recognition or understanding
    • G06V2201/03—Recognition of patterns in medical or anatomical images

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  • Engineering & Computer Science (AREA)
  • Theoretical Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Multimedia (AREA)
  • Databases & Information Systems (AREA)
  • Biomedical Technology (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Evolutionary Computation (AREA)
  • Software Systems (AREA)
  • Computing Systems (AREA)
  • Artificial Intelligence (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Quality & Reliability (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DK18729159.6T 2017-06-15 2018-06-12 Fremgangsmåde til træning af en deep learning-model for at opnå histopatologisk information fra billeder DK3639191T4 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP17176214 2017-06-15
PCT/EP2018/065504 WO2018229052A1 (en) 2017-06-15 2018-06-12 Method for training a deep learning model to obtain histopathological information from images

Publications (2)

Publication Number Publication Date
DK3639191T3 DK3639191T3 (da) 2021-12-06
DK3639191T4 true DK3639191T4 (da) 2024-09-30

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DK18729159.6T DK3639191T4 (da) 2017-06-15 2018-06-12 Fremgangsmåde til træning af en deep learning-model for at opnå histopatologisk information fra billeder

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US (1) US11276165B2 (da)
EP (1) EP3639191B2 (da)
DK (1) DK3639191T4 (da)
WO (1) WO2018229052A1 (da)

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WO2021134508A1 (zh) * 2019-12-31 2021-07-08 深圳迈瑞生物医疗电子股份有限公司 一种细胞图像分析装置和样本分析方法
WO2021188617A1 (en) * 2020-03-18 2021-09-23 Sanofi Systems and methods for predicting expression levels
US20240029409A1 (en) * 2020-08-18 2024-01-25 Newtron Group Sa Tissue staining and sequential imaging of biological samples for deep learning image analysis and virtual staining
CN112101451B (zh) * 2020-09-14 2024-01-05 北京联合大学 一种基于生成对抗网络筛选图像块的乳腺癌组织病理类型分类方法
DE102020212189A1 (de) * 2020-09-28 2022-03-31 Siemens Healthcare Gmbh Verfahren und Vorrichtung zur Analyse von Histopathologiedatensätzen
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CN113256618A (zh) * 2021-06-23 2021-08-13 重庆点检生物科技有限公司 一种基于ihc染色的肿瘤识别系统及方法
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CN114399764B (zh) * 2021-12-29 2025-09-26 宁波江丰生物信息技术有限公司 一种病理切片的扫描方法及系统
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WO2024011400A1 (zh) * 2022-07-12 2024-01-18 福州迈新生物技术开发有限公司 生成用于计算浸润性乳腺癌细胞Ki-67计数的训练数据的方法、存储设备和试剂盒
CN115240000B (zh) * 2022-07-22 2023-05-02 司法鉴定科学研究院 一种用于法医鉴定的糖尿病检测装置及方法
CN116993972A (zh) * 2022-10-26 2023-11-03 腾讯科技（深圳）有限公司 实例分割模型的训练方法、装置、服务器及存储介质
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US11276165B2 (en) 2022-03-15
EP3639191B1 (en) 2021-09-01
EP3639191A1 (en) 2020-04-22
EP3639191B2 (en) 2024-07-17
US20210150701A1 (en) 2021-05-20
WO2018229052A1 (en) 2018-12-20
DK3639191T3 (da) 2021-12-06

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