DK367189A - T-pa-derivat og dets fremstilling - Google Patents

T-pa-derivat og dets fremstilling Download PDF

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Publication number
DK367189A
DK367189A DK367189A DK367189A DK367189A DK 367189 A DK367189 A DK 367189A DK 367189 A DK367189 A DK 367189A DK 367189 A DK367189 A DK 367189A DK 367189 A DK367189 A DK 367189A
Authority
DK
Denmark
Prior art keywords
derivatives
manufacturing
Prior art date
Application number
DK367189A
Other languages
English (en)
Other versions
DK367189D0 (da
Inventor
Ulrich Weidle
Ralf Mattes
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of DK367189D0 publication Critical patent/DK367189D0/da
Publication of DK367189A publication Critical patent/DK367189A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • C12N9/6459—Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21069—Protein C activated (3.4.21.69)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK367189A 1988-07-25 1989-07-25 T-pa-derivat og dets fremstilling DK367189A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3825253A DE3825253A1 (de) 1988-07-25 1988-07-25 T-pa-derivat und seine herstellung

Publications (2)

Publication Number Publication Date
DK367189D0 DK367189D0 (da) 1989-07-25
DK367189A true DK367189A (da) 1990-01-26

Family

ID=6359511

Family Applications (1)

Application Number Title Priority Date Filing Date
DK367189A DK367189A (da) 1988-07-25 1989-07-25 T-pa-derivat og dets fremstilling

Country Status (4)

Country Link
EP (1) EP0352710A3 (da)
JP (1) JPH02107187A (da)
DE (1) DE3825253A1 (da)
DK (1) DK367189A (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0542869T3 (da) * 1990-07-31 1996-02-05 Genentech Inc Vævsplasminogenaktivatorvarianter med nedsat udskillelse
DE10153601A1 (de) 2001-11-02 2003-05-22 Paion Gmbh DSPA zur Behandlung von Schlaganfall
DE10342518A1 (de) * 2003-09-12 2005-05-12 Paion Gmbh Plasminogen-Aktivatoren mit verringerter Lysin-Bindungskapazität

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3687651T2 (de) * 1985-12-20 1993-06-24 Upjohn Co Analoge des gewebespezifischen plasminogenaktivators.
DE3643158A1 (de) * 1986-04-21 1987-11-19 Boehringer Mannheim Gmbh Gewebs-plasminogen-aktivator(tpa) - derivat und seine herstellung

Also Published As

Publication number Publication date
DE3825253A1 (de) 1990-02-01
DK367189D0 (da) 1989-07-25
JPH02107187A (ja) 1990-04-19
EP0352710A3 (de) 1990-05-02
EP0352710A2 (de) 1990-01-31

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment