DK3692040T3 - Kemiske forbindelser - Google Patents
Kemiske forbindelser Download PDFInfo
- Publication number
- DK3692040T3 DK3692040T3 DK18795809.5T DK18795809T DK3692040T3 DK 3692040 T3 DK3692040 T3 DK 3692040T3 DK 18795809 T DK18795809 T DK 18795809T DK 3692040 T3 DK3692040 T3 DK 3692040T3
- Authority
- DK
- Denmark
- Prior art keywords
- chemical compounds
- compounds
- chemical
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/438—The ring being spiro-condensed with carbocyclic or heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/20—Spiro-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762568633P | 2017-10-05 | 2017-10-05 | |
| US201762570509P | 2017-10-10 | 2017-10-10 | |
| US201862681146P | 2018-06-06 | 2018-06-06 | |
| US201862683859P | 2018-06-12 | 2018-06-12 | |
| PCT/IB2018/057767 WO2019069293A1 (en) | 2017-10-05 | 2018-10-05 | CHEMICAL COMPOUNDS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3692040T3 true DK3692040T3 (da) | 2023-03-13 |
Family
ID=64049476
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK18795809.5T DK3692040T3 (da) | 2017-10-05 | 2018-10-05 | Kemiske forbindelser |
Country Status (27)
| Country | Link |
|---|---|
| US (3) | US20200255428A1 (da) |
| EP (2) | EP4180431A1 (da) |
| JP (1) | JP7248665B2 (da) |
| KR (1) | KR102705376B1 (da) |
| CN (2) | CN111433206B (da) |
| AU (2) | AU2018344926A1 (da) |
| CA (1) | CA3078312A1 (da) |
| CL (1) | CL2020000912A1 (da) |
| CO (1) | CO2020004202A2 (da) |
| CY (1) | CY1125888T1 (da) |
| DK (1) | DK3692040T3 (da) |
| ES (1) | ES2940263T3 (da) |
| FI (1) | FI3692040T3 (da) |
| HR (1) | HRP20230274T1 (da) |
| HU (1) | HUE061380T2 (da) |
| IL (1) | IL273769B2 (da) |
| LT (1) | LT3692040T (da) |
| MX (1) | MX2020003382A (da) |
| MY (1) | MY201605A (da) |
| PH (1) | PH12020550145A1 (da) |
| PL (1) | PL3692040T3 (da) |
| PT (1) | PT3692040T (da) |
| RS (1) | RS64043B1 (da) |
| SG (2) | SG10202111648YA (da) |
| SI (1) | SI3692040T1 (da) |
| SM (1) | SMT202300089T1 (da) |
| WO (1) | WO2019069293A1 (da) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016183266A1 (en) | 2015-05-13 | 2016-11-17 | Enanta Pharmaceuticals, Inc. | Ehpatitis b antiviral agents |
| KR102398439B1 (ko) | 2016-03-07 | 2022-05-16 | 이난타 파마슈티칼스, 인코포레이티드 | B형 간염 항바이러스제 |
| CN116751200A (zh) * | 2016-11-07 | 2023-09-15 | 爱彼特生物制药公司 | 含有取代的吡啶酮的三环化合物以及使用其的方法 |
| EA202090514A1 (ru) | 2017-08-28 | 2020-06-24 | Энанта Фармасьютикалс, Инк. | Противовирусное средство против гепатита в |
| WO2019143902A2 (en) | 2018-01-22 | 2019-07-25 | Enanta Pharmaceuticals, Inc. | Substituted heterocycles as antiviral agents |
| US10729688B2 (en) | 2018-03-29 | 2020-08-04 | Enanta Pharmaceuticals, Inc. | Hepatitis B antiviral agents |
| WO2019233941A1 (en) | 2018-06-05 | 2019-12-12 | F. Hoffmann-La Roche Ag | Tetrahydro-1 h-pyrazino[2,1 -ajisoindolylquinoline compounds for the treatment of autoimmune disease |
| WO2019246427A1 (en) * | 2018-06-22 | 2019-12-26 | Arbutus Biopharma Corporation | Crystalline forms of pyridinone-containing tricyclic compounds and methods of preparing and using same |
| US12128044B2 (en) | 2018-08-28 | 2024-10-29 | Sunshine Lake Pharma Co., Ltd. | Fused tricyclic compounds and uses thereof in medicine |
| CA3113235A1 (en) | 2018-09-21 | 2020-03-26 | Enanta Pharmaceuticals, Inc. | Functionalized heterocycles as antiviral agents |
| EP3856740A4 (en) | 2018-09-30 | 2021-12-15 | Sunshine Lake Pharma Co., Ltd. | CONDENSED TETRACYCLIC COMPOUNDS AND USES THEREOF IN MEDICINE |
| IL283190B2 (en) | 2018-11-21 | 2025-08-01 | Enanta Pharm Inc | Functionalized heterocycles as antiviral agents |
| CN111217811B (zh) * | 2018-11-26 | 2024-01-16 | 广东东阳光药业股份有限公司 | 稠合三环类化合物及其在药物中的应用 |
| TW202104214A (zh) | 2019-04-05 | 2021-02-01 | 英商葛蘭素史密斯克藍智慧財產發展有限公司 | 化合物 |
| US11236111B2 (en) | 2019-06-03 | 2022-02-01 | Enanta Pharmaceuticals, Inc. | Hepatitis B antiviral agents |
| WO2020247561A1 (en) | 2019-06-04 | 2020-12-10 | Enanta Pharmaceuticals, Inc, | Hepatitis b antiviral agents |
| WO2020247575A1 (en) | 2019-06-04 | 2020-12-10 | Enanta Pharmaceuticals, Inc. | Hepatitis b antiviral agents |
| WO2021007488A1 (en) | 2019-07-11 | 2021-01-14 | Enanta Pharmaceuticals, Inc. | Substituted heterocycles as antiviral agents |
| US11236108B2 (en) | 2019-09-17 | 2022-02-01 | Enanta Pharmaceuticals, Inc. | Functionalized heterocycles as antiviral agents |
| US11802125B2 (en) | 2020-03-16 | 2023-10-31 | Enanta Pharmaceuticals, Inc. | Functionalized heterocyclic compounds as antiviral agents |
| CN113173911A (zh) * | 2021-04-20 | 2021-07-27 | 梯尔希（南京）药物研发有限公司 | 吡虫啉代谢物5-羟基吡虫啉的合成方法 |
| KR20240144245A (ko) | 2022-01-28 | 2024-10-02 | 글락소스미스클라인 인털렉츄얼 프로퍼티 디벨로프먼트 리미티드 | B형 간염 바이러스 감염을 치료하기 위한 조합 요법 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2017504633A (ja) * | 2014-01-30 | 2017-02-09 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | Ｂ型肝炎ウイルス感染の治療及び予防のための新規なジヒドロキノリジノン |
| CA2948080A1 (en) * | 2014-05-13 | 2015-11-19 | F. Hoffmann-La Roche Ag | Novel dihydroquinolizinones for the treatment and prophylaxis of hepatitis b virus infection |
| US9637485B2 (en) * | 2014-11-03 | 2017-05-02 | Hoffmann-La Roche Inc. | 6,7-dihydrobenzo[a]quinolizin-2-one derivatives for the treatment and prophylaxis of hepatitis B virus infection |
| EP3256471B1 (en) * | 2015-02-11 | 2018-12-12 | F. Hoffmann-La Roche AG | Novel 2-oxo-6,7-dihydrobenzo[a]quinolizine-3-carboxylic acid derivatives for the treatment and prophylaxis of hepatitis b virus infection |
| WO2017108630A1 (en) * | 2015-12-21 | 2017-06-29 | F. Hoffmann-La Roche Ag | Combination therapy of an hbsag inhibitor and an hbv capsid assembly inhibitor |
| TW201811788A (zh) * | 2016-09-09 | 2018-04-01 | 瑞士商諾華公司 | 作為抗病毒劑之多環吡啶酮化合物 |
| CN116751200A (zh) * | 2016-11-07 | 2023-09-15 | 爱彼特生物制药公司 | 含有取代的吡啶酮的三环化合物以及使用其的方法 |
| CN106810548B (zh) * | 2017-01-13 | 2019-02-15 | 苏州爱科百发生物医药技术有限公司 | 一种二氢异喹啉类化合物 |
| CN108727378A (zh) * | 2017-04-19 | 2018-11-02 | 银杏树药业(苏州)有限公司 | 新型异喹啉类化合物及其医药用途 |
-
2018
- 2018-10-05 RS RS20230207A patent/RS64043B1/sr unknown
- 2018-10-05 SI SI201830862T patent/SI3692040T1/sl unknown
- 2018-10-05 DK DK18795809.5T patent/DK3692040T3/da active
- 2018-10-05 MY MYPI2020001721A patent/MY201605A/en unknown
- 2018-10-05 CN CN201880078910.8A patent/CN111433206B/zh active Active
- 2018-10-05 JP JP2020519410A patent/JP7248665B2/ja active Active
- 2018-10-05 SM SM20230089T patent/SMT202300089T1/it unknown
- 2018-10-05 SG SG10202111648YA patent/SG10202111648YA/en unknown
- 2018-10-05 AU AU2018344926A patent/AU2018344926A1/en not_active Abandoned
- 2018-10-05 PT PT187958095T patent/PT3692040T/pt unknown
- 2018-10-05 ES ES18795809T patent/ES2940263T3/es active Active
- 2018-10-05 LT LTEPPCT/IB2018/057767T patent/LT3692040T/lt unknown
- 2018-10-05 PL PL18795809.5T patent/PL3692040T3/pl unknown
- 2018-10-05 EP EP22214773.8A patent/EP4180431A1/en active Pending
- 2018-10-05 HU HUE18795809A patent/HUE061380T2/hu unknown
- 2018-10-05 MX MX2020003382A patent/MX2020003382A/es unknown
- 2018-10-05 EP EP18795809.5A patent/EP3692040B1/en active Active
- 2018-10-05 CA CA3078312A patent/CA3078312A1/en active Pending
- 2018-10-05 KR KR1020207012236A patent/KR102705376B1/ko active Active
- 2018-10-05 US US16/753,645 patent/US20200255428A1/en not_active Abandoned
- 2018-10-05 HR HRP20230274TT patent/HRP20230274T1/hr unknown
- 2018-10-05 WO PCT/IB2018/057767 patent/WO2019069293A1/en not_active Ceased
- 2018-10-05 IL IL273769A patent/IL273769B2/en unknown
- 2018-10-05 SG SG11202002771XA patent/SG11202002771XA/en unknown
- 2018-10-05 CN CN202310780889.9A patent/CN116942663A/zh active Pending
- 2018-10-05 FI FIEP18795809.5T patent/FI3692040T3/fi active
-
2020
- 2020-03-25 PH PH12020550145A patent/PH12020550145A1/en unknown
- 2020-04-03 CL CL2020000912A patent/CL2020000912A1/es unknown
- 2020-04-03 CO CONC2020/0004202A patent/CO2020004202A2/es unknown
-
2021
- 2021-06-04 AU AU2021203650A patent/AU2021203650B9/en active Active
- 2021-10-25 US US17/509,769 patent/US12221444B2/en active Active
-
2023
- 2023-03-16 CY CY20231100145T patent/CY1125888T1/el unknown
-
2024
- 2024-11-11 US US18/943,115 patent/US20250066361A1/en active Pending
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