DK369588A - 1-substituerede 7-diazabicycloalkyl-6-fluor-4-oxo-1,4-dihydroquinolin-3-carboxylsyre-forbindelser og antibakterielle farmaceutiske praeparater indeholdende disse samt mellemprodukter ved deres fremstilling - Google Patents

1-substituerede 7-diazabicycloalkyl-6-fluor-4-oxo-1,4-dihydroquinolin-3-carboxylsyre-forbindelser og antibakterielle farmaceutiske praeparater indeholdende disse samt mellemprodukter ved deres fremstilling

Info

Publication number
DK369588A
DK369588A DK369588A DK369588A DK369588A DK 369588 A DK369588 A DK 369588A DK 369588 A DK369588 A DK 369588A DK 369588 A DK369588 A DK 369588A DK 369588 A DK369588 A DK 369588A
Authority
DK
Denmark
Prior art keywords
drugs
diazabicycloalkyl
dihydroquinoline
fluor
oxo
Prior art date
Application number
DK369588A
Other languages
English (en)
Other versions
DK369588D0 (da
Inventor
Edward Fox Kleinman
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of DK369588D0 publication Critical patent/DK369588D0/da
Publication of DK369588A publication Critical patent/DK369588A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK369588A 1987-07-02 1988-07-01 1-substituerede 7-diazabicycloalkyl-6-fluor-4-oxo-1,4-dihydroquinolin-3-carboxylsyre-forbindelser og antibakterielle farmaceutiske praeparater indeholdende disse samt mellemprodukter ved deres fremstilling DK369588A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1987/001583 WO1989000158A1 (en) 1987-07-02 1987-07-02 Bridged-diazabicycloalkyl quinolone carboxylic acids and esters

Publications (2)

Publication Number Publication Date
DK369588D0 DK369588D0 (da) 1988-07-01
DK369588A true DK369588A (da) 1989-01-03

Family

ID=22202448

Family Applications (1)

Application Number Title Priority Date Filing Date
DK369588A DK369588A (da) 1987-07-02 1988-07-01 1-substituerede 7-diazabicycloalkyl-6-fluor-4-oxo-1,4-dihydroquinolin-3-carboxylsyre-forbindelser og antibakterielle farmaceutiske praeparater indeholdende disse samt mellemprodukter ved deres fremstilling

Country Status (6)

Country Link
EP (1) EP0297858A3 (da)
JP (1) JPH0686450B2 (da)
DK (1) DK369588A (da)
FI (1) FI890983A0 (da)
PT (1) PT87884A (da)
WO (1) WO1989000158A1 (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1336090C (en) * 1988-08-31 1995-06-27 Isao Hayakawa Spiro-substituted cyclic amines of quinolone derivatives
US5286723A (en) * 1988-08-31 1994-02-15 Daiichi Seiyaku Co., Ltd. Spiro compound
US7214686B2 (en) 1997-06-30 2007-05-08 Targacept, Inc. Pharmaceutical compositions and methods for effecting dopamine release
DK1519939T5 (da) 2002-07-05 2011-01-24 Targacept Inc N-Aryl-diazaspirocykliske forbindelser og fremgangsmåder til fremstilling og anvendelse deraf
WO2004009775A2 (en) 2002-07-19 2004-01-29 Targacept, Inc. Methods and compositions relating to chimeric nicotinic receptor subunits
US7098331B2 (en) 2003-03-05 2006-08-29 Targacept, Inc. Arylvinylazacycloalkane compounds and methods of preparation and use thereof
OA13050A (en) 2003-04-29 2006-11-10 Pfizer Ltd 5,7-diaminopyrazolo [4,3-D] pyrimidines useful in the treatment of hypertension.
WO2005037832A2 (en) 2003-10-15 2005-04-28 Targacept, Inc. Azabicycyclic compounds for relieving pain and treating central nervous system disorders
US7572799B2 (en) 2003-11-24 2009-08-11 Pfizer Inc Pyrazolo[4,3-d]pyrimidines as Phosphodiesterase Inhibitors
CA2562251C (en) 2004-04-07 2009-04-28 Pfizer Inc. Pyrazolo'4,3-d pyrimidines
CN101044134A (zh) 2004-09-20 2007-09-26 塔加西普特公司 具有烟碱性胆碱能受体活性的氮杂螺烯和氮杂螺烷化合物
UA88792C2 (ru) 2004-11-10 2009-11-25 Таргасепт, Інк. Гидроксибензоатные соли метаникотиновых соединений
US7459469B2 (en) 2004-11-10 2008-12-02 Targacept, Inc. Hydroxybenzoate salts of metanicotine compounds
US7732607B2 (en) 2005-08-22 2010-06-08 Anatoly Mazurov Heteroaryl-substituted diazatricycloalkanes and methods of use thereof
US8017785B2 (en) 2006-05-09 2011-09-13 Astrazeneca Ab Salt forms of (2S)-(4E)-N-methyl-5-[3-(5-isopropoxypyridin)y1]-4-penten 2-amine
TWI389889B (zh) 2006-05-09 2013-03-21 Targacept Inc （２ｓ）-（４ｅ）-ｎ-甲基-５-〔３-（５-異丙氧基吡啶）基〕-４-戊烯-２-胺之新穎多晶型
WO2009046025A1 (en) 2007-10-01 2009-04-09 Comentis, Inc. Quinuclidin-4-ylmethyl 1h-indole-3-carboxylate derivatives as alpha 7 nicotinic acetylcholine receptor ligands for the treatment of alzheimer's disease
US8802694B2 (en) 2009-12-07 2014-08-12 Targacept, Inc. 3,6-diazabicyclo[3.1.1]heptanes as neuronal nicotinic acetycholine receptor ligands
CN103180277A (zh) 2010-05-20 2013-06-26 塔格塞普特股份有限公司 制备芳基取代的烯属胺的新方法
JP2017524736A (ja) 2014-07-11 2017-08-31 アルファーマゲン，エルエルシー アルファ７−ニコチン性アセチルコリン受容体活性を調節するためのキヌクリジン化合物

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3947445A (en) * 1974-05-09 1976-03-30 Stanford Research Institute Diazabicyclooctanes and diazabicycloheptanes
US3954766A (en) * 1975-07-09 1976-05-04 Stanford Research Institute 1,4-Diazabicyclo[3.2.1]octanes
LU77362A1 (da) * 1977-05-17 1979-01-19
DE2726571A1 (de) * 1977-06-13 1978-12-21 Basf Ag Neue bispidinderivate, verfahren zu deren herstellung und arzneimittel, welche diese enthalten
US4665079A (en) * 1984-02-17 1987-05-12 Warner-Lambert Company Antibacterial agents
DE3234697A1 (de) * 1982-09-18 1984-03-22 Kali-Chemie Pharma Gmbh, 3000 Hannover Neue diazabicyclo-(3,3,1)-nonane
US4571396A (en) * 1984-04-16 1986-02-18 Warner-Lambert Company Antibacterial agents
US4578473A (en) * 1985-04-15 1986-03-25 Warner-Lambert Company Process for quinoline-3-carboxylic acid antibacterial agents
IN166416B (da) * 1985-09-18 1990-05-05 Pfizer
DE3601567A1 (de) * 1986-01-21 1987-07-23 Bayer Ag 7-(azabicycloalkyl)-chinoloncarbonsaeure- und -naphthyridon-carbonsaeure-derivate

Also Published As

Publication number Publication date
PT87884A (pt) 1989-06-30
EP0297858A3 (en) 1990-05-30
JPH0686450B2 (ja) 1994-11-02
EP0297858A2 (en) 1989-01-04
WO1989000158A1 (en) 1989-01-12
JPS6416783A (en) 1989-01-20
FI890983A7 (fi) 1989-03-01
FI890983A0 (fi) 1989-03-01
DK369588D0 (da) 1988-07-01

Similar Documents

Publication Publication Date Title
DK369588D0 (da) 1-substituerede 7-diazabicycloalkyl-6-fluor-4-oxo-1,4-dihydroquinolin-3-carboxylsyre-forbindelser og antibakterielle farmaceutiske praeparater indeholdende disse samt mellemprodukter ved deres fremstilling
DK359986D0 (da) Phenylethere, fremgangsmaader til fremstilling samt farmaceutiske midler indeholdende disse
DK25992A (da) Quinolinderivater, deres fremstilling samt farmaeutisk praeparat indeholdende saadanne derivater
DK290986D0 (da) 2-arylimidazolforbindelser, laegemidler indeholdende disse forbindelser og deres fremstilling
DK231687A (da) Heterocykliske forbindelser, deres fremstilling og anvendelse, samt laegemidler indeholdende disse forbindelser
DK518687A (da) Imidazo-benzoxazinoner, deres fremstilling og laegemidler indholdende forbindelserne
NO308287B1 (no) Substituerte 4-fenyl-6-amino-nikotinsyrederivater, legemidler inneholdende disse samt deres anvendelse
DK160986C (da) Ferrikomplekser, deres anvendelse samt farmaceutiske praeparater indeholdende disse
DK161383C (da) Quinolincarboxylsyre-derivat, fremgangsmaade til fremstilling heraf samt antibakterielle farmaceutiske praeparater indeholdende dette
DK166279C (da) 3,4-dihydro-2h-benzooebaapyranderivater, deres fremstilling og laegemidler indeholdende disse forbindelser
DK642588D0 (da) Indanderivater, fremgangsmaade til fremstilling deraf samt farmaceutiske praeparater indeholdende samme
DK165367C (da) Imidazolylalkylguanidinderivater, fremgangsmaade til fremstilling heraf samt laegemidler indeholdende disse forbindelser
DK592189A (da) Nitroimidazoler, fremgangsmaade til fremstilling deraf samt farmaceutiske praeparater indeholdende samme
DK66086D0 (da) Dihydropyridiner, fremgangsmaader til fremstilling heraf samt farmaceutiske midler indeholdende disse
DK170788D0 (da) Dihydropyridazinonderivater, fremgangsmaader til fremstilling heraf samt laegemidler indeholdende disse
NO880474D0 (no) Alkylsubstituerte n-benzopyranyllaktaner, fremgangsmaate til deres fremstilling, deres anvendelse samt farmasoeytiske preparater paa basis av disse forbindelser.
DK143188D0 (da) Farmaceutiske praeparater indeholdende pyranoquinolinforbindelser samt deres anvendelse
DK469189A (da) Substituerede thienopyraner, fremgangsmaade til fremstilling deraf samt farmaceutiske praeparater indeholdende samme
DK307085A (da) 4-phenyl-2-trifluormethyl-1,3-dioxan-5-ylheptensyrederivater, fremgangsmaade til fremstilling deraf samt farmaceutiske midler indeholdende disse
DK162984C (da) 1-(2-ar-2-halogen-2-ethenyl)-1h-azoler, fremgangsmaade til deres fremstilling samt farmaceutiske praeparater indeholdende disse
NO863461D0 (no) 3-desmetyl-mevalonsyrederivater, fremgangsmaate til deres fremstilling, farmasoeytiske preparater paa basis av disse forbindelser, deres anvendelse, samt mellomprodukter.
NO883609D0 (no) Farmasoeytiske preparater for topisk anvendelse.
DK449989A (da) Quinolinderivater, deres fremstilling og laegemidler indeholdende disse derivater
DK65986A (da) Dihydropyridiner, fremgangsmaader til fremstilling heraf samt farmaceutiske midler indeholdende disse
DK610388D0 (da) (6-(hetero) aryloxy-naphthalin-2-yl-oxy)-alkancarboxylsyrederivater, deres fremstilling og anvendelse samt ved fremgangsmaaden anvendelige mellemprodukter og disses fremstilling

Legal Events

Date Code Title Description
AHS Application shelved for other reasons than non-payment