DK3700513T3 - Ikke-steroide selektive glucocorticoidreceptor-agonistiske modulatorer (segram) og anvendelser deraf - Google Patents

Ikke-steroide selektive glucocorticoidreceptor-agonistiske modulatorer (segram) og anvendelser deraf Download PDF

Info

Publication number: DK3700513T3
Authority: DK; Denmark
Prior art keywords: segram; steroid; receptor agonist; glucocorticoid receptor; selective glucocorticoid
Prior art date: 2017-10-27

Application number

DK18786823.7T

Other languages

English (en)

Inventor

Pierre Chambon

Guoqiang Hua

Original Assignee

Association Pour La Rech A Ligbmc Ari

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2017-10-27

Filing date

2018-10-23

Publication date

2022-11-28

2018-05-17 Priority claimed from EP18305612.6A external-priority patent/EP3569228A1/en

2018-10-23 Application filed by Association Pour La Rech A Ligbmc Ari filed Critical Association Pour La Rech A Ligbmc Ari

2022-11-28 Application granted granted Critical

2022-11-28 Publication of DK3700513T3 publication Critical patent/DK3700513T3/da

Links

JFUAWXPBHXKZGA-IBGZPJMESA-N 4-fluoro-2-[(4r)-5,5,5-trifluoro-4-hydroxy-2-methyl-4-(1h-pyrrolo[2,3-c]pyridin-2-ylmethyl)pentan-2-yl]phenol Chemical compound C([C@@](O)(CC=1NC2=CN=CC=C2C=1)C(F)(F)F)C(C)(C)C1=CC(F)=CC=C1O JFUAWXPBHXKZGA-IBGZPJMESA-N 0.000 title 1
229940124750 glucocorticoid receptor agonist Drugs 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
- C07D307/88—Benzo [c] furans; Hydrogenated benzo [c] furans with one oxygen atom directly attached in position 1 or 3

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pulmonology (AREA)
Dermatology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Emergency Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

DK18786823.7T 2017-10-27 2018-10-23 Ikke-steroide selektive glucocorticoidreceptor-agonistiske modulatorer (segram) og anvendelser deraf DK3700513T3 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US201762578036P	2017-10-27	2017-10-27
EP18305612.6A EP3569228A1 (en)	2018-05-17	2018-05-17	Non-steroidal selective glucocorticoid receptor agonistic modulators (segrams) and uses thereof
PCT/EP2018/079049 WO2019081517A2 (en)	2017-10-27	2018-10-23	NON-STEROIDIC GLUCOCORTICOIC RECEPTOR (SEGRAM) RECEPTOR AGONIST MODULATORS AND USES THEREOF

Publications (1)

Publication Number	Publication Date
DK3700513T3 true DK3700513T3 (da)	2022-11-28

Family

ID=63862176

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK18786823.7T DK3700513T3 (da)	2017-10-27	2018-10-23	Ikke-steroide selektive glucocorticoidreceptor-agonistiske modulatorer (segram) og anvendelser deraf

Country Status (7)

Country	Link
US (1)	US20190151283A1 (da)
DK (1)	DK3700513T3 (da)
ES (1)	ES2932076T3 (da)
FI (1)	FI3700513T3 (da)
IL (1)	IL274208A (da)
PL (1)	PL3700513T3 (da)
WO (1)	WO2019081517A2 (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP3569228A1 (en) *	2018-05-17	2019-11-20	Association pour la recherche à l'IGBMC (ARI)	Non-steroidal selective glucocorticoid receptor agonistic modulators (segrams) and uses thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5262165A (en)	1992-02-04	1993-11-16	Schering Corporation	Transdermal nitroglycerin patch with penetration enhancers
US6010715A (en)	1992-04-01	2000-01-04	Bertek, Inc.	Transdermal patch incorporating a polymer film incorporated with an active agent
HU228434B1 (en)	1995-06-07	2013-03-28	Ortho Mcneil Pharm Inc	Transdermal medicament for administering 17-deacetyl norgestimate alone or in combination with an estrogen
US6245804B1 (en)	1997-05-30	2001-06-12	Schering Aktiengesellschaft	Nonsteroidal gestagens
US5948433A (en)	1997-08-21	1999-09-07	Bertek, Inc.	Transdermal patch
DE19856475A1 (de)	1998-11-27	2000-05-31	Schering Ag	Nichtsteroidale Entzündungshemmer
DE10038639A1 (de) *	2000-07-28	2002-02-21	Schering Ag	Nichtsteroidale Entzündungshemmer

2018
- 2018-10-23 ES ES18786823T patent/ES2932076T3/es active Active
- 2018-10-23 DK DK18786823.7T patent/DK3700513T3/da active
- 2018-10-23 US US16/167,971 patent/US20190151283A1/en not_active Abandoned
- 2018-10-23 WO PCT/EP2018/079049 patent/WO2019081517A2/en not_active Ceased
- 2018-10-23 FI FIEP18786823.7T patent/FI3700513T3/fi active
- 2018-10-23 PL PL18786823.7T patent/PL3700513T3/pl unknown
2020
- 2020-04-24 IL IL274208A patent/IL274208A/en unknown

Also Published As

Publication number	Publication date
PL3700513T3 (pl)	2023-01-09
ES2932076T3 (es)	2023-01-11
WO2019081517A3 (en)	2019-06-20
IL274208A (en)	2020-06-30
FI3700513T3 (fi)	2022-12-15
WO2019081517A2 (en)	2019-05-02
US20190151283A1 (en)	2019-05-23

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