DK3712265T5 - Makrofag apoptosehæmmer varitant - Google Patents

Makrofag apoptosehæmmer varitant Download PDF

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Publication number
DK3712265T5
DK3712265T5 DK18877418.6T DK18877418T DK3712265T5 DK 3712265 T5 DK3712265 T5 DK 3712265T5 DK 18877418 T DK18877418 T DK 18877418T DK 3712265 T5 DK3712265 T5 DK 3712265T5
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Prior art keywords
apoptosis inhibitor
macrophage apoptosis
inhibitor variant
variant
macrophage
Prior art date
Application number
DK18877418.6T
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English (en)
Other versions
DK3712265T3 (da
Inventor
Satoko Arai
Toru Miyazaki
Original Assignee
Toru Miyazaki
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Publication date
Application filed by Toru Miyazaki filed Critical Toru Miyazaki
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Publication of DK3712265T3 publication Critical patent/DK3712265T3/da
Publication of DK3712265T5 publication Critical patent/DK3712265T5/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702Regulators; Modulating activity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70596Molecules with a "CD"-designation not provided for elsewhere
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/50Fusion polypeptide containing protease site

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK18877418.6T 2017-11-16 2018-10-09 Makrofag apoptosehæmmer varitant DK3712265T5 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2017220733 2017-11-16
PCT/JP2018/037505 WO2019097898A1 (ja) 2017-11-16 2018-10-09 変異型aim

Publications (2)

Publication Number Publication Date
DK3712265T3 DK3712265T3 (da) 2024-03-11
DK3712265T5 true DK3712265T5 (da) 2024-08-26

Family

ID=66539641

Family Applications (1)

Application Number Title Priority Date Filing Date
DK18877418.6T DK3712265T5 (da) 2017-11-16 2018-10-09 Makrofag apoptosehæmmer varitant

Country Status (8)

Country Link
US (2) US11866471B2 (da)
EP (1) EP3712265B1 (da)
JP (1) JP7231230B2 (da)
CN (1) CN111315880B (da)
DK (1) DK3712265T5 (da)
ES (1) ES2974545T3 (da)
PT (1) PT3712265T (da)
WO (1) WO2019097898A1 (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7504490B2 (ja) 2022-09-01 2024-06-24 合同会社AiMIYA 重度腎不全に罹患するネコ科動物における尿毒症の悪化を抑制するための剤
CN116982600B (zh) * 2023-09-14 2025-11-18 江苏集萃药康生物科技股份有限公司 一种cd69人源化小鼠模型的构建方法及其应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6046314A (en) * 1997-03-06 2000-04-04 Bristol-Myers Squibb Co. Spα: a novel scavenger receptor cysteine-rich domain-containing polypeptide, and monoclonal antibodies thereto
US20100331244A1 (en) 2009-06-01 2010-12-30 The University Of Tokyo Pharmaceutical composition, food or drink, and methods related thereto
US20130115220A1 (en) 2010-05-20 2013-05-09 Dainippon Sumitomo Pharma Co., Ltd. Method for prevention or treatment of metabolic syndrome
JP6143015B2 (ja) * 2012-04-27 2017-06-07 宮崎 徹 肝疾患の予防または治療剤
WO2015119253A1 (ja) 2014-02-07 2015-08-13 宮崎 徹 腎疾患の予防または治療剤
JP6083549B1 (ja) 2016-06-03 2017-02-22 株式会社制御システム研究所 特定パケット中継機能付きデータダイオード装置
JP7289033B2 (ja) * 2018-10-01 2023-06-09 徹 宮崎 神経変性疾患治療剤

Also Published As

Publication number Publication date
JP7231230B2 (ja) 2023-03-01
WO2019097898A1 (ja) 2019-05-23
ES2974545T3 (es) 2024-06-27
EP3712265A4 (en) 2021-08-25
DK3712265T3 (da) 2024-03-11
US20230212238A1 (en) 2023-07-06
EP3712265A1 (en) 2020-09-23
CN111315880B (zh) 2023-10-31
EP3712265B1 (en) 2024-01-10
JPWO2019097898A1 (ja) 2021-02-04
US20200399332A1 (en) 2020-12-24
PT3712265T (pt) 2024-03-12
CN111315880A (zh) 2020-06-19
US11866471B2 (en) 2024-01-09

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