DK3717636T5 - Adeno-associeret-virus-variantcapsider og anvendelse til inhibering af angiogenese - Google Patents

Adeno-associeret-virus-variantcapsider og anvendelse til inhibering af angiogenese Download PDF

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Publication number
DK3717636T5
DK3717636T5 DK18881166.5T DK18881166T DK3717636T5 DK 3717636 T5 DK3717636 T5 DK 3717636T5 DK 18881166 T DK18881166 T DK 18881166T DK 3717636 T5 DK3717636 T5 DK 3717636T5
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adeno
inhibiting angiogenesis
virus variant
variant capsids
capsids
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DK18881166.5T
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DK3717636T3 (da
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Melissa Kotterman
David Schaffer
Paul Szymanski
Peter Francis
David Kirn
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4D Molecular Therapeutics Inc
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    • A61K48/0008—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition
    • A—HUMAN NECESSITIES
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    • C07—ORGANIC CHEMISTRY
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    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
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    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
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    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14141—Use of virus, viral particle or viral elements as a vector
    • C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14141—Use of virus, viral particle or viral elements as a vector
    • C12N2750/14145—Special targeting system for viral vectors

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  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Virology (AREA)
  • General Engineering & Computer Science (AREA)
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  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
DK18881166.5T 2017-11-27 2018-11-26 Adeno-associeret-virus-variantcapsider og anvendelse til inhibering af angiogenese DK3717636T5 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762590976P 2017-11-27 2017-11-27
US201862664726P 2018-04-30 2018-04-30
PCT/US2018/062478 WO2019104279A1 (en) 2017-11-27 2018-11-26 Adeno-associated virus variant capsids and use for inhibiting angiogenesis

Publications (2)

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DK3717636T3 DK3717636T3 (da) 2023-05-30
DK3717636T5 true DK3717636T5 (da) 2024-08-26

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US (1) US11766489B2 (da)
EP (3) EP3717636B1 (da)
JP (4) JP7184894B2 (da)
KR (2) KR102793696B1 (da)
CN (1) CN111770999A (da)
AU (3) AU2018372235B9 (da)
BR (1) BR112020010674A2 (da)
CA (1) CA3083472A1 (da)
CL (1) CL2020001360A1 (da)
CR (1) CR20200282A (da)
DK (1) DK3717636T5 (da)
ES (1) ES2946747T3 (da)
FI (1) FI3717636T3 (da)
IL (1) IL274712A (da)
MX (1) MX2020005451A (da)
PE (1) PE20210915A1 (da)
PH (1) PH12020550706A1 (da)
PT (1) PT3717636T (da)
SG (1) SG11202004545XA (da)
UA (1) UA127831C2 (da)
WO (1) WO2019104279A1 (da)

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