DK3720883T5 - T-celler omfattende kimære anti-cd38- og anti-cd138-antigenreceptorer og anvendelser deraf - Google Patents

T-celler omfattende kimære anti-cd38- og anti-cd138-antigenreceptorer og anvendelser deraf Download PDF

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DK3720883T5
DK3720883T5 DK18886875.6T DK18886875T DK3720883T5 DK 3720883 T5 DK3720883 T5 DK 3720883T5 DK 18886875 T DK18886875 T DK 18886875T DK 3720883 T5 DK3720883 T5 DK 3720883T5
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antigen receptors
cell comprehensive
chimeric anti
comprehensive chimeric
cell
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DK18886875.6T
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DK3720883T3 (da
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Zelig Eshhar
Tova Waks
Levin Anat Globerson
Slobodkin Moran Rawet
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Medical Res Infrastructure & Health Services Fund Tel Aviv Medical Ct
Yeda Res & Dev
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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    • A61K39/001126—CD38 not IgG
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    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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DK18886875.6T 2017-12-05 2018-12-04 T-celler omfattende kimære anti-cd38- og anti-cd138-antigenreceptorer og anvendelser deraf DK3720883T5 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762594577P 2017-12-05 2017-12-05
US201862667638P 2018-05-07 2018-05-07
PCT/IL2018/051325 WO2019111249A1 (en) 2017-12-05 2018-12-04 T-cells comprising anti-cd38 and anti-cd138 chimeric antigen receptors and uses thereof

Publications (2)

Publication Number Publication Date
DK3720883T3 DK3720883T3 (da) 2023-07-24
DK3720883T5 true DK3720883T5 (da) 2024-08-26

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DK18886875.6T DK3720883T5 (da) 2017-12-05 2018-12-04 T-celler omfattende kimære anti-cd38- og anti-cd138-antigenreceptorer og anvendelser deraf

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US (2) US11944644B2 (da)
EP (1) EP3720883B1 (da)
JP (2) JP7437705B2 (da)
CN (1) CN111587254B (da)
DK (1) DK3720883T5 (da)
ES (1) ES2949855T3 (da)
IL (2) IL316570A (da)
PL (1) PL3720883T3 (da)
WO (1) WO2019111249A1 (da)

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JP2022537066A (ja) * 2019-06-21 2022-08-23 シャタック ラボ，インコーポレイテッド キメラタンパク質を発現するｔ細胞
CN111484563B (zh) * 2020-04-30 2020-11-10 徐州医科大学附属医院 一种抗cd38嵌合抗原受体及其应用
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WO2024052318A1 (en) * 2022-09-06 2024-03-14 Institut National de la Santé et de la Recherche Médicale Novel dual split car-t cells for the treatment of cd38-positive hematological malignancies
WO2024102954A1 (en) 2022-11-10 2024-05-16 Massachusetts Institute Of Technology Activation induced clipping system (aics)
EP4688860A2 (en) * 2023-03-28 2026-02-11 Nkarta, Inc. Antibodies and chimeric antigen receptors specific for cd38

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CN110582509A (zh) 2017-01-31 2019-12-17 诺华股份有限公司 使用具有多特异性的嵌合t细胞受体蛋白治疗癌症
CN107326014B (zh) * 2017-07-31 2019-09-24 时力生物科技（北京）有限公司 一种双特异性嵌合抗原受体修饰的t淋巴细胞及其制备方法和应用
EP3720882A4 (en) 2017-12-05 2021-10-27 The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center T-CELLS WITH TWO DIFFERENT CHIMERIC ANTIGEN RECEPTORS AND THEIR USE

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JP2021517820A (ja) 2021-07-29
JP7437705B2 (ja) 2024-02-26
EP3720883A1 (en) 2020-10-14
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EP3720883B1 (en) 2023-04-19
DK3720883T3 (da) 2023-07-24
US20200384024A1 (en) 2020-12-10
US11944644B2 (en) 2024-04-02
CN111587254B (zh) 2025-02-25
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