DK3721980T3 - Mikrofluidindretning til emulsionsfremstilling - Google Patents

Mikrofluidindretning til emulsionsfremstilling Download PDF

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Publication number
DK3721980T3
DK3721980T3 DK19305477.2T DK19305477T DK3721980T3 DK 3721980 T3 DK3721980 T3 DK 3721980T3 DK 19305477 T DK19305477 T DK 19305477T DK 3721980 T3 DK3721980 T3 DK 3721980T3
Authority
DK
Denmark
Prior art keywords
microfluidic device
emulsion production
emulsion
production
microfluidic
Prior art date
Application number
DK19305477.2T
Other languages
English (en)
Inventor
Nicolas Bremond
Jérôme Bibette
Gwénaëlle Bazin
Original Assignee
Paris Sciences Et Lettres
Centre Nat Rech Scient
Ecole Superieure Physique & Chimie Ind Ville De Paris
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Paris Sciences Et Lettres, Centre Nat Rech Scient, Ecole Superieure Physique & Chimie Ind Ville De Paris filed Critical Paris Sciences Et Lettres
Application granted granted Critical
Publication of DK3721980T3 publication Critical patent/DK3721980T3/da

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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/40Mixing liquids with liquids; Emulsifying
    • B01F23/41Emulsifying
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30Micromixers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5025Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures for parallel transport of multiple samples
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/40Mixing liquids with liquids; Emulsifying
    • B01F23/41Emulsifying
    • B01F23/4105Methods of emulsifying
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/40Mixing liquids with liquids; Emulsifying
    • B01F23/41Emulsifying
    • B01F23/413Homogenising a raw emulsion or making monodisperse or fine emulsions
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/40Mixing liquids with liquids; Emulsifying
    • B01F23/41Emulsifying
    • B01F23/414Emulsifying characterised by the internal structure of the emulsion
    • B01F23/4143Microemulsions
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/30Injector mixers
    • B01F25/31Injector mixers in conduits or tubes through which the main component flows
    • B01F25/314Injector mixers in conduits or tubes through which the main component flows wherein additional components are introduced at the circumference of the conduit
    • B01F25/3142Injector mixers in conduits or tubes through which the main component flows wherein additional components are introduced at the circumference of the conduit the conduit having a plurality of openings in the axial direction or in the circumferential direction
    • B01F25/31422Injector mixers in conduits or tubes through which the main component flows wherein additional components are introduced at the circumference of the conduit the conduit having a plurality of openings in the axial direction or in the circumferential direction with a plurality of perforations in the axial direction only
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30Micromixers
    • B01F33/3035Micromixers using surface tension to mix, move or hold the fluids
    • B01F33/30351Micromixers using surface tension to mix, move or hold the fluids using hydrophilic/hydrophobic surfaces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0819Microarrays; Biochips
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0861Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0867Multiple inlets and one sample wells, e.g. mixing, dilution
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/16Surface properties and coatings
    • B01L2300/161Control and use of surface tension forces, e.g. hydrophobic, hydrophilic
    • B01L2300/165Specific details about hydrophobic, oleophobic surfaces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Colloid Chemistry (AREA)
DK19305477.2T 2019-04-12 2019-04-12 Mikrofluidindretning til emulsionsfremstilling DK3721980T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP19305477.2A EP3721980B1 (en) 2019-04-12 2019-04-12 Emulsion production microfluidic device

Publications (1)

Publication Number Publication Date
DK3721980T3 true DK3721980T3 (da) 2022-10-10

Family

ID=67396895

Family Applications (1)

Application Number Title Priority Date Filing Date
DK19305477.2T DK3721980T3 (da) 2019-04-12 2019-04-12 Mikrofluidindretning til emulsionsfremstilling

Country Status (11)

Country Link
US (1) US12172155B2 (da)
EP (1) EP3721980B1 (da)
JP (1) JP7607267B2 (da)
KR (1) KR102911593B1 (da)
CN (1) CN113853249B (da)
CA (1) CA3132526A1 (da)
DK (1) DK3721980T3 (da)
ES (1) ES2928237T3 (da)
PL (1) PL3721980T3 (da)
PT (1) PT3721980T (da)
WO (1) WO2020208121A1 (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3895794A1 (en) * 2020-04-15 2021-10-20 HighFly Therapeutics (HK) Limited Method and system of producing hydrogel microspheres
CN119140185A (zh) * 2023-06-16 2024-12-17 深圳麦科田生物医疗技术股份有限公司 微流控芯片
CN119140186A (zh) * 2023-06-16 2024-12-17 深圳麦科田生物医疗技术股份有限公司 微流控芯片

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004103539A2 (en) * 2003-05-16 2004-12-02 Velocys Inc. Process for forming an emulsion using microchannel process technology
CN1265199C (zh) * 2004-07-13 2006-07-19 东南大学 一种基于微球的微流控生物芯片
US20070048192A1 (en) * 2005-08-10 2007-03-01 Emil Kartalov Integrated microfluidic vias, overpasses, underpasses, septums, microfuses, nested bioarrays and methods for fabricating the same
US20090042241A1 (en) * 2007-04-06 2009-02-12 California Institute Of Technology Microfluidic device
NL2002862C2 (en) * 2009-05-08 2010-11-09 Friesland Brands Bv Microfluidic apparatus and method for generating a dispersion.
WO2011028764A2 (en) * 2009-09-02 2011-03-10 President And Fellows Of Harvard College Multiple emulsions created using jetting and other techniques
CN103226127B (zh) * 2013-03-27 2015-02-18 清华大学 一种多通道微流控芯片-质谱联用装置
US10151429B2 (en) * 2013-05-14 2018-12-11 President And Fellows Of Harvard College Rapid production of droplets
US10662470B2 (en) * 2015-03-16 2020-05-26 Luminex Corporation Apparatus and methods for multi-step channel emulsification
GB201506807D0 (en) * 2015-04-22 2015-06-03 Univ Leicester An emulsion
CN106975411B (zh) * 2017-05-05 2020-01-10 北京大学 基于3d打印的微流控芯片及包括该芯片的乳液产生装置
CN108393103A (zh) * 2018-03-03 2018-08-14 北京工业大学 一种可实现液滴尺寸不依赖流量的微流控芯片
CN108671970B (zh) * 2018-04-11 2020-07-14 华南师范大学 一种基于微流控芯片的双尺寸微液滴的产生方法
CN109012774B (zh) * 2018-08-10 2022-03-15 深圳先进技术研究院 液滴生成装置、液滴微流控芯片及应用

Also Published As

Publication number Publication date
US20220203354A1 (en) 2022-06-30
JP2022528471A (ja) 2022-06-10
EP3721980A1 (en) 2020-10-14
EP3721980B1 (en) 2022-07-06
JP7607267B2 (ja) 2024-12-27
CA3132526A1 (en) 2020-10-15
WO2020208121A1 (en) 2020-10-15
PT3721980T (pt) 2022-10-13
KR20220022892A (ko) 2022-02-28
CN113853249A (zh) 2021-12-28
ES2928237T3 (es) 2022-11-16
US12172155B2 (en) 2024-12-24
CN113853249B (zh) 2024-09-20
KR102911593B1 (ko) 2026-01-14
PL3721980T3 (pl) 2023-04-17

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