DK3722436T3 - Fixed-bed-bioreaktor med pumpe/rør-system med konstant flow - Google Patents
Fixed-bed-bioreaktor med pumpe/rør-system med konstant flowInfo
- Publication number
- DK3722436T3 DK3722436T3 DK20176020.4T DK20176020T DK3722436T3 DK 3722436 T3 DK3722436 T3 DK 3722436T3 DK 20176020 T DK20176020 T DK 20176020T DK 3722436 T3 DK3722436 T3 DK 3722436T3
- Authority
- DK
- Denmark
- Prior art keywords
- fixed
- constant flow
- pipe system
- flow pump
- bed bioreactor
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M1/00—Apparatus for enzymology or microbiology
- C12M1/02—Apparatus for enzymology or microbiology with agitation means; with heat exchange means
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
- C12M25/16—Particles; Beads; Granular material; Encapsulation
- C12M25/18—Fixed or packed bed
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
- C12M29/10—Perfusion
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
- C12M29/18—External loop; Means for reintroduction of fermented biomass or liquid percolate
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/26—Means for regulation, monitoring, measurement or control, e.g. flow regulation of pH
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/46—Means for regulation, monitoring, measurement or control, e.g. flow regulation of cellular or enzymatic activity or functionality, e.g. cell viability
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
- C12N2740/15051—Methods of production or purification of viral material
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Sustainable Development (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662322651P | 2016-04-14 | 2016-04-14 | |
| EP17782838.1A EP3442986A4 (en) | 2016-04-14 | 2017-04-03 | FIXED BAYOR ACTUATOR WITH CONSTANT FLOW PUMP / PIPING SYSTEM |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3722436T3 true DK3722436T3 (da) | 2025-12-15 |
Family
ID=60042678
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK20176020.4T DK3722436T3 (da) | 2016-04-14 | 2017-04-03 | Fixed-bed-bioreaktor med pumpe/rør-system med konstant flow |
| DK20176019.6T DK3722435T3 (da) | 2016-04-14 | 2017-04-03 | Fixed-bed-bioreaktor med pumpe/rør-system med konstant flow |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK20176019.6T DK3722435T3 (da) | 2016-04-14 | 2017-04-03 | Fixed-bed-bioreaktor med pumpe/rør-system med konstant flow |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US11781102B2 (da) |
| EP (4) | EP3604547A1 (da) |
| KR (1) | KR102535013B1 (da) |
| CN (1) | CN109071594A (da) |
| CA (1) | CA3021070A1 (da) |
| DK (2) | DK3722436T3 (da) |
| PT (1) | PT3722435T (da) |
| SG (1) | SG11201808698TA (da) |
| WO (1) | WO2017180341A2 (da) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116144500A (zh) | 2016-04-14 | 2023-05-23 | 崔泽尔有限公司 | 具有恒流泵/管道系统的固定床生物反应器 |
| EP3604547A1 (en) | 2016-04-14 | 2020-02-05 | Trizell Ltd. | Fixed-bed bioreactor with constant-flow pump/tubing system |
| BE1026108B1 (fr) * | 2018-03-16 | 2019-10-14 | Univercells S.A. | Échantillonneur à lit fixe et procédés associés |
| JP2022532498A (ja) * | 2019-05-02 | 2022-07-15 | アレフ ファームス リミテッド | 培養システムおよび培養食品の大量生産方法 |
| US20220403307A1 (en) * | 2019-11-06 | 2022-12-22 | I Peace, Inc. | Cell culture device |
| CN113832112A (zh) * | 2020-06-24 | 2021-12-24 | 重庆精准生物技术有限公司 | 一种制备慢病毒的混合方法及混合系统 |
| US20230146372A1 (en) * | 2021-11-07 | 2023-05-11 | Univercells Technologies S.A. | Sampling apparatus for cell culture bed and related methods |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS63313576A (ja) * | 1987-06-13 | 1988-12-21 | Rikagaku Kenkyusho | チユ−ブラ−バイオリアクタ− |
| US5622857A (en) * | 1995-08-08 | 1997-04-22 | Genespan Corporation | High performance cell culture bioreactor and method |
| WO1998022588A2 (en) * | 1996-11-20 | 1998-05-28 | Introgen Therapeutics, Inc. | An improved method for the production and purification of adenoviral vectors |
| ZA200406921B (en) * | 2002-03-12 | 2006-10-25 | Ark Therapeutics Ltd | Engineered baculoviruses and their use |
| CA2557046A1 (en) * | 2004-03-05 | 2005-10-13 | John Crowley | Process for cell culturing by continuous perfusion and alternating tangential flow |
| US20110189764A1 (en) * | 2011-03-27 | 2011-08-04 | Nathan Starbard | Single use device incorporating a container and scaffold |
| US20140315294A1 (en) * | 2011-11-24 | 2014-10-23 | Genethon | Scalable lentiviral vector production system compatible with industrial pharmaceutical applications |
| HUE042094T2 (hu) * | 2013-02-22 | 2019-06-28 | Genzyme Corp | Mikrokarrier-perfúziós tenyésztési eljárások és alkalmazásuk |
| AU2014226126B2 (en) * | 2013-03-08 | 2019-02-14 | Genzyme Corporation | Continuous purification of therapeutic proteins |
| GB201417042D0 (en) * | 2014-09-29 | 2014-11-12 | Fkd Therapies Oy | Method |
| CN116144500A (zh) | 2016-04-14 | 2023-05-23 | 崔泽尔有限公司 | 具有恒流泵/管道系统的固定床生物反应器 |
| EP3604547A1 (en) | 2016-04-14 | 2020-02-05 | Trizell Ltd. | Fixed-bed bioreactor with constant-flow pump/tubing system |
-
2017
- 2017-04-03 EP EP19196877.5A patent/EP3604547A1/en not_active Withdrawn
- 2017-04-03 DK DK20176020.4T patent/DK3722436T3/da active
- 2017-04-03 CA CA3021070A patent/CA3021070A1/en active Pending
- 2017-04-03 DK DK20176019.6T patent/DK3722435T3/da active
- 2017-04-03 PT PT201760196T patent/PT3722435T/pt unknown
- 2017-04-03 SG SG11201808698TA patent/SG11201808698TA/en unknown
- 2017-04-03 EP EP20176019.6A patent/EP3722435B1/en active Active
- 2017-04-03 KR KR1020187032704A patent/KR102535013B1/ko active Active
- 2017-04-03 CN CN201780023830.8A patent/CN109071594A/zh active Pending
- 2017-04-03 WO PCT/US2017/025681 patent/WO2017180341A2/en not_active Ceased
- 2017-04-03 EP EP17782838.1A patent/EP3442986A4/en not_active Withdrawn
- 2017-04-03 EP EP20176020.4A patent/EP3722436B1/en active Active
- 2017-04-25 US US15/777,228 patent/US11781102B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP3722435A1 (en) | 2020-10-14 |
| WO2017180341A3 (en) | 2017-11-23 |
| PT3722435T (pt) | 2025-09-22 |
| EP3722436B1 (en) | 2025-09-24 |
| CA3021070A1 (en) | 2017-10-19 |
| WO2017180341A4 (en) | 2018-01-11 |
| SG11201808698TA (en) | 2018-11-29 |
| KR102535013B1 (ko) | 2023-05-22 |
| KR20180133487A (ko) | 2018-12-14 |
| EP3442986A4 (en) | 2019-11-13 |
| US11781102B2 (en) | 2023-10-10 |
| WO2017180341A2 (en) | 2017-10-19 |
| US20200165557A1 (en) | 2020-05-28 |
| EP3722436A1 (en) | 2020-10-14 |
| DK3722435T3 (da) | 2025-11-17 |
| EP3722435B1 (en) | 2025-09-03 |
| EP3442986A2 (en) | 2019-02-20 |
| CN109071594A (zh) | 2018-12-21 |
| EP3604547A1 (en) | 2020-02-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SI3722435T1 (sl) | Bioreaktor s fiksno posteljo s sistemom črpalke/cevnim sistemom s konstantnim pretokom | |
| EP4026893C0 (en) | FLUID PUMP AND BIOREACTOR SYSTEM | |
| DK3722436T3 (da) | Fixed-bed-bioreaktor med pumpe/rør-system med konstant flow | |
| DK3760795T3 (da) | Væskeforsyningssystem | |
| DK3230459T3 (da) | Rekombinante mikroorganismer med øget strømning gennem en fermenteringsbane | |
| DK3353456T3 (da) | Rørforbindelse med sensor | |
| PL3102829T3 (pl) | Bezimpulsowa pompa wyporowa i sposób bezimpulsowego przemieszczania płynu | |
| DK2971920T3 (da) | Rørforbindelse med automatisk forbindelse | |
| EP3337371C0 (en) | WATER DRAG DETECTION SYSTEM | |
| EP3804782C0 (en) | FLOW SENSOR SYSTEM WITH CONNECTION ASSEMBLY | |
| FR3017438B1 (fr) | Conduite flexible de transport de fluide et procede associe | |
| DE112015004508A5 (de) | Fluidführungssystem | |
| DK3380131T3 (da) | Implanterbart fluidpumpesystem | |
| BR112018005885A2 (pt) | sistema de fluido. | |
| DK3092084T3 (da) | Aseptisk rørledningsgris med identifikationsmidler | |
| BR112018005757A2 (pt) | sistema de fluido. | |
| EP3200745C0 (en) | LIQUID TRANSFER SYSTEM | |
| DK3242990T3 (da) | Boresystem med flere væsker | |
| DK3925693T3 (da) | Fluidtanksystem | |
| BR112016024662A2 (pt) | estrutura de fluxo de fluido | |
| BR112017014211A2 (pt) | sistema de purificação de líquido. | |
| BR112017002317A2 (pt) | estrutura de redirecionamento de fluido | |
| DK3317544T3 (da) | Fristrømspumpe | |
| LT3104758T (lt) | Prijungimo dėžės sistema centrinėms valymo siurblių sistemoms | |
| FR3017183B1 (fr) | Installation de delivrance de liquide cryogenique |