DK3759108T3 - Polyprolin-mimetika af prolin-afledt modul 15 - Google Patents

Polyprolin-mimetika af prolin-afledt modul 15 Download PDF

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Publication number
DK3759108T3
DK3759108T3 DK19706670.7T DK19706670T DK3759108T3 DK 3759108 T3 DK3759108 T3 DK 3759108T3 DK 19706670 T DK19706670 T DK 19706670T DK 3759108 T3 DK3759108 T3 DK 3759108T3
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DK
Denmark
Prior art keywords
polyproline
mimetics
proline
derived module
derived
Prior art date
Application number
DK19706670.7T
Other languages
English (en)
Other versions
DK3759108T5 (da
Inventor
Ronald Kühne
Hans-Günther Schmalz
Stephan Dohmen
Matthias Barone
Matthias Müller
Slim Chiha
Dominik Albat
Original Assignee
Forschungsverbund Berlin Ev
Univ Koeln
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Forschungsverbund Berlin Ev, Univ Koeln filed Critical Forschungsverbund Berlin Ev
Publication of DK3759108T3 publication Critical patent/DK3759108T3/da
Application granted granted Critical
Publication of DK3759108T5 publication Critical patent/DK3759108T5/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK19706670.7T 2018-02-26 2019-02-26 Polyprolin-mimetika af prolin-afledt modul 15 DK3759108T5 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP18158650 2018-02-26
EP18175731 2018-06-04
PCT/EP2019/054715 WO2019162524A1 (de) 2018-02-26 2019-02-26 Polyprolin-mimetika des prolin-abgeleiteten moduls-15

Publications (2)

Publication Number Publication Date
DK3759108T3 true DK3759108T3 (da) 2023-11-27
DK3759108T5 DK3759108T5 (da) 2024-08-26

Family

ID=65516662

Family Applications (1)

Application Number Title Priority Date Filing Date
DK19706670.7T DK3759108T5 (da) 2018-02-26 2019-02-26 Polyprolin-mimetika af prolin-afledt modul 15

Country Status (6)

Country Link
US (1) US12195466B2 (da)
EP (1) EP3759108B1 (da)
DK (1) DK3759108T5 (da)
ES (1) ES2964378T3 (da)
PL (1) PL3759108T3 (da)
WO (1) WO2019162524A1 (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4729523A1 (en) 2024-10-16 2026-04-22 Prosion GmbH Bicyclic dipeptide mimetics and their use
EP4729520A1 (en) 2024-10-16 2026-04-22 Prosion GmbH Conformationally fixed diproline mimetics and their use

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2094711B8 (de) 2006-09-25 2018-03-28 Forschungsverbund Berlin e.V. Strukturmimetika prolinreicher peptide und ihre pharmazeutische verwendung
EP2561873A1 (de) 2011-08-26 2013-02-27 Forschungsverbund Berlin e.V. Strukturmimetika prolinreicher Peptide und ihre Verwendung
EP3230300B1 (de) 2014-12-11 2021-11-24 Forschungsverbund Berlin E.V. Inhibitoren zur hemmung der tumormetastasierung

Also Published As

Publication number Publication date
ES2964378T3 (es) 2024-04-05
EP3759108B1 (de) 2023-08-30
WO2019162524A1 (de) 2019-08-29
US20210332050A1 (en) 2021-10-28
EP3759108A1 (de) 2021-01-06
DK3759108T5 (da) 2024-08-26
US12195466B2 (en) 2025-01-14
PL3759108T3 (pl) 2024-02-26

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