DK3765525T5 - Biparatopiske anti-her2-antistof-lægemiddelkonjugater og anvendelsesfremgangsmåder - Google Patents

Biparatopiske anti-her2-antistof-lægemiddelkonjugater og anvendelsesfremgangsmåder Download PDF

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DK3765525T5
DK3765525T5 DK19766478.2T DK19766478T DK3765525T5 DK 3765525 T5 DK3765525 T5 DK 3765525T5 DK 19766478 T DK19766478 T DK 19766478T DK 3765525 T5 DK3765525 T5 DK 3765525T5
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stof
methods
drug conjugates
her2
biparatopic
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DK19766478.2T
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DK3765525T3 (da
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Kevin Hamblett
Rupert H Davies
James R Rich
Gerald J Rowse
Vincent K C Fung
Stuart D Barnscher
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Zymeworks Bc Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/6425—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the peptide or protein in the drug conjugate being a receptor, e.g. CD4, a cell surface antigen, i.e. not a peptide ligand targeting the antigen, or a cell surface determinant, i.e. a part of the surface of a cell
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