DK3777858T3 - Middel til at hæmme stigning af intraneuronal calciumkoncentration - Google Patents

Middel til at hæmme stigning af intraneuronal calciumkoncentration Download PDF

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Publication number
DK3777858T3
DK3777858T3 DK19776508.4T DK19776508T DK3777858T3 DK 3777858 T3 DK3777858 T3 DK 3777858T3 DK 19776508 T DK19776508 T DK 19776508T DK 3777858 T3 DK3777858 T3 DK 3777858T3
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DK
Denmark
Prior art keywords
inhibit
agent
increase
calcium concentration
intraneuronal calcium
Prior art date
Application number
DK19776508.4T
Other languages
English (en)
Inventor
Kanako SERIZAWA
Kazumi Nishimura
Tomohiko Suzuki
Tatsuya Nishi
Original Assignee
Toray Industries
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toray Industries filed Critical Toray Industries
Application granted granted Critical
Publication of DK3777858T3 publication Critical patent/DK3777858T3/da

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41781,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
DK19776508.4T 2018-03-30 2019-03-29 Middel til at hæmme stigning af intraneuronal calciumkoncentration DK3777858T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2018066541 2018-03-30
PCT/JP2019/014045 WO2019189781A1 (ja) 2018-03-30 2019-03-29 神経細胞内カルシウム濃度上昇抑制剤

Publications (1)

Publication Number Publication Date
DK3777858T3 true DK3777858T3 (da) 2025-05-12

Family

ID=68062015

Family Applications (1)

Application Number Title Priority Date Filing Date
DK19776508.4T DK3777858T3 (da) 2018-03-30 2019-03-29 Middel til at hæmme stigning af intraneuronal calciumkoncentration

Country Status (13)

Country Link
US (1) US11510914B2 (da)
EP (1) EP3777858B1 (da)
JP (1) JP7264158B2 (da)
KR (1) KR102780996B1 (da)
CN (1) CN111902143B (da)
AU (1) AU2019242521B2 (da)
BR (1) BR112020019284A2 (da)
CA (1) CA3095723A1 (da)
DK (1) DK3777858T3 (da)
ES (1) ES3023985T3 (da)
PL (1) PL3777858T3 (da)
TW (1) TWI812692B (da)
WO (1) WO2019189781A1 (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI884935B (zh) * 2018-12-26 2025-06-01 日商東麗股份有限公司 作為神經細胞骨架蛋白質機能促進劑之環狀胺衍生物以及新穎環狀胺衍生物之醫藥用途
WO2021153743A1 (ja) * 2020-01-31 2021-08-05 東レ株式会社 環状アミン誘導体の結晶及びその医薬用途
WO2021172488A1 (ja) * 2020-02-28 2021-09-02 東レ株式会社 環状アミン誘導体及びその医薬用途
TW202330471A (zh) * 2021-09-30 2023-08-01 日商住友製藥股份有限公司 環丙醯胺衍生物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6906072B1 (en) 2000-01-20 2005-06-14 Eisai Co., Ltd. Piperazine compound and pharmaceutical composition containing the compound
TW200621677A (en) 2004-09-21 2006-07-01 Astellas Pharma Inc Cyclic amine derivative or salt thereof
WO2013147160A1 (ja) * 2012-03-29 2013-10-03 東レ株式会社 環状アミン誘導体及びその医薬用途
CN107250128B (zh) 2015-02-27 2019-07-26 东丽株式会社 环状胺衍生物和其医药用途
JP6859068B2 (ja) 2016-10-21 2021-04-14 東芝キヤリア株式会社 空気調和機の制御方法、空気調和機

Also Published As

Publication number Publication date
CA3095723A1 (en) 2019-10-03
PL3777858T3 (pl) 2025-06-02
AU2019242521A1 (en) 2020-10-08
KR102780996B1 (ko) 2025-03-14
US11510914B2 (en) 2022-11-29
CN111902143B (zh) 2024-01-02
EP3777858A1 (en) 2021-02-17
RU2020135329A (ru) 2022-05-04
CN111902143A (zh) 2020-11-06
TWI812692B (zh) 2023-08-21
ES3023985T3 (en) 2025-06-03
EP3777858B1 (en) 2025-04-02
EP3777858A4 (en) 2022-03-02
AU2019242521B2 (en) 2024-04-18
KR20200136895A (ko) 2020-12-08
TW202002974A (zh) 2020-01-16
US20210023068A1 (en) 2021-01-28
JPWO2019189781A1 (ja) 2021-04-08
BR112020019284A2 (pt) 2021-01-05
JP7264158B2 (ja) 2023-04-25
WO2019189781A1 (ja) 2019-10-03

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