DK384185A - Ekspressionsvektorer - Google Patents

Ekspressionsvektorer Download PDF

Info

Publication number
DK384185A
DK384185A DK384185A DK384185A DK384185A DK 384185 A DK384185 A DK 384185A DK 384185 A DK384185 A DK 384185A DK 384185 A DK384185 A DK 384185A DK 384185 A DK384185 A DK 384185A
Authority
DK
Denmark
Prior art keywords
dna sequence
contg
vector
host cell
gene
Prior art date
Application number
DK384185A
Other languages
English (en)
Other versions
DK384185D0 (da
Inventor
Haim Aviv
Daniel Bartfeld
Marian Gorecki
Jacob R Hartman
Dov Kanner
Avigdor Levanon
Original Assignee
Bio Technology General Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/644,105 external-priority patent/US4742004A/en
Application filed by Bio Technology General Corp filed Critical Bio Technology General Corp
Publication of DK384185D0 publication Critical patent/DK384185D0/da
Publication of DK384185A publication Critical patent/DK384185A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0089—Oxidoreductases (1.) acting on superoxide as acceptor (1.15)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/775—Apolipopeptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C12N15/69—Increasing the copy number of the vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C12N15/73—Expression systems using phage (lambda) regulatory sequences
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK384185A 1984-08-27 1985-08-23 Ekspressionsvektorer DK384185A (da)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US64511984A 1984-08-27 1984-08-27
US64467184A 1984-08-27 1984-08-27
US64424584A 1984-08-27 1984-08-27
US64455184A 1984-08-27 1984-08-27
US06/644,105 US4742004A (en) 1984-08-27 1984-08-27 Method for producing enzymatically active eucaryotic sod in bacteria

Publications (2)

Publication Number Publication Date
DK384185D0 DK384185D0 (da) 1985-08-23
DK384185A true DK384185A (da) 1986-02-28

Family

ID=27542038

Family Applications (1)

Application Number Title Priority Date Filing Date
DK384185A DK384185A (da) 1984-08-27 1985-08-23 Ekspressionsvektorer

Country Status (15)

Country Link
EP (2) EP0483113B1 (da)
JP (4) JP2933280B2 (da)
AT (2) ATE184916T1 (da)
AU (1) AU603331B2 (da)
CA (2) CA1340597C (da)
DE (2) DE3586473T2 (da)
DK (1) DK384185A (da)
GR (1) GR852030B (da)
HK (1) HK151695A (da)
HU (2) HU214977B (da)
IE (1) IE61141B1 (da)
IL (3) IL110039A (da)
MY (1) MY130321A (da)
NZ (1) NZ213154A (da)
PT (1) PT81025B (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU582536B2 (en) * 1983-04-29 1989-04-06 Yeda Research And Development Co. Ltd. Human superoxide dismutase cdna
BG49718A3 (bg) * 1983-07-15 1992-01-15 Bio- Technology General Corp Метод за получаване на полипептид със супероксиддисмутазна активност
ATE69618T1 (de) * 1983-10-03 1991-12-15 Chiron Corp Klonieren von superoxid-dismutase und expression in mikroorganismen.
CA1267615A (en) * 1984-08-27 1990-04-10 Dan Hadary Method for recovering purified growth hormones from genetically engineered microorganisms
JP2594535B2 (ja) * 1984-11-30 1997-03-26 サントリー株式会社 高発現ベクターおよびその利用
US5037806A (en) * 1985-02-22 1991-08-06 Monsanto Company Biologically active method using somatotropins
WO1987002062A1 (en) * 1985-10-04 1987-04-09 Biotechnology Research Partners, Ltd. Recombinant apolipoproteins and methods
GB8701848D0 (en) * 1987-01-28 1987-03-04 Celltech Ltd Polypeptides
IL96136A (en) * 1989-11-07 2000-12-06 Bio Technology General Corp Use of hydrophobic chromatography in a method for purification of copper-zinc superoxide dismutase from cells containing same
WO1991007496A1 (en) * 1989-11-09 1991-05-30 Allied-Signal Inc. Cloning and expression of genes encoding for polypeptides comprised of one or more repeating amino acid sequences
DE4239877C1 (de) * 1992-11-27 1994-03-17 Boehringer Ingelheim Int Stabilisierte Superoxid-Dismutase (SOD)-Zusammensetzung
GB9303988D0 (en) * 1993-02-26 1993-04-14 Health Lab Service Board Bi-functional expression systems
US6030810A (en) * 1997-02-26 2000-02-29 Delgado; Stephen Gregory Cloned tetrodotoxin-sensitive sodium channel α-subunit and a splice variant thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK143412C (da) * 1979-05-17 1982-05-24 Forenede Bryggerier As Fremgangsmaade til udvinding af cu,zn-superoxid-dismutase fra gaer
IE63126B1 (en) * 1980-06-06 1995-03-22 Biogen Inc Improved vectors and methods for making such vectors and for expressing cloned genes
US4506013A (en) * 1980-10-03 1985-03-19 Eli Lilly And Company Stabilizing and selecting recombinant DNA host cells
CA1341012C (en) * 1982-09-27 2000-06-06 Biogen, Inc. Dna sequences, recombinant dna molecules and processes for producing swine growth hormone-like polypeptides
WO1984002918A1 (fr) * 1983-01-21 1984-08-02 Transgene Sa NOUVEAUX VECTEURS D'EXPRESSION ET LEUR APPLICATION A LA PREPARATION D'UNE PROTEINE AYANT L'ACTIVITE DE L'ANTITRYPSINE-alpha1 HUMAINE
BG49718A3 (bg) * 1983-07-15 1992-01-15 Bio- Technology General Corp Метод за получаване на полипептид със супероксиддисмутазна активност
DE3486452T2 (de) * 1983-10-03 1997-11-06 Chiron Corp., Emeryville, Calif. Superoxiddismutase und deren Expression in Mikroorganismen

Also Published As

Publication number Publication date
IL76192A0 (en) 1985-12-31
JP2688180B2 (ja) 1997-12-08
DE3586473T2 (de) 1993-02-04
GR852030B (da) 1985-12-30
DE3588216T2 (de) 2000-02-03
HK151695A (en) 1995-09-29
AU4667785A (en) 1986-03-06
PT81025B (pt) 1988-01-22
ATE184916T1 (de) 1999-10-15
JP2777074B2 (ja) 1998-07-16
DE3586473D1 (de) 1992-09-17
IL110039A (en) 1996-12-05
CA1340464C (en) 1999-03-23
NZ213154A (en) 1988-11-29
HUT40697A (en) 1987-01-28
PT81025A (en) 1985-09-01
EP0173280A1 (en) 1986-03-05
HU214977B (hu) 1998-08-28
DK384185D0 (da) 1985-08-23
IE852093L (en) 1986-02-27
IE61141B1 (en) 1994-10-05
IL76192A (en) 1996-12-05
JPH08283296A (ja) 1996-10-29
MY130321A (en) 2007-06-29
IL108976A (en) 1996-12-05
EP0483113A3 (en) 1992-05-13
HU215160B (hu) 1998-10-28
ATE79407T1 (de) 1992-08-15
CA1340597C (en) 1999-06-22
JPH07222596A (ja) 1995-08-22
JPS61111693A (ja) 1986-05-29
EP0173280B1 (en) 1992-08-12
DE3588216D1 (de) 1999-10-28
EP0483113A2 (en) 1992-04-29
IL108976A0 (en) 1994-06-24
JP2933280B2 (ja) 1999-08-09
IL110039A0 (en) 1994-10-07
AU603331B2 (en) 1990-11-15
EP0483113B1 (en) 1999-09-22
JPH07236490A (ja) 1995-09-12

Similar Documents

Publication Publication Date Title
AU603331B2 (en) Expression vectors containing LAMBDA PL promoter, and engineered restriction site for convenient replacement of ribosomal binding site, plasmids containing the vectors, hosts containing the plasmids and related methods
IL173399A0 (en) Circular dna molecule with conditional origin of replication which contains nucleic acid of interest and selection marker but does not encode its replication initiation protein, method for preparing the same and use thereof in gene therapy
DK320686A (da) Ekspressionskontrolsekvenser
ATE27000T1 (de) Expression von polypeptiden in hefen.
HUT47321A (en) Process for inducing virus resistance in plants
GR852940B (da)
ES8304199A1 (es) Un procedimiento para la produccion de un plasmido.
EP0164992A3 (en) Nitrogen fixation regulator genes
ES8700321A1 (es) Un metodo para la produccion de polipeptidos codificados por un adn.
EP0187630A3 (en) Cloned streptomyces beta-galactosidase gene
WO1996007745A3 (fr) Vecteurs de criblage et/ou d'expression fonctionnels chez les mycobacteries
EP0164245A3 (en) Nif promoter of rhizobium japonicum
ES554327A0 (es) Un procedimiento para preparar un plasmido recombinante
EP0154539A3 (en) Recombinant dna expression vectors and method for gene expression
HUP9903075A2 (hu) Sejtciklus ellenőrzőpont gének
ES2008391A6 (es) Un metodo para producir isopenicilina n sintetasa.
Makeeva et al. Construction and properties of a hybrid operon coding the HBcAG and beta-galactosidase of the hepatitis B virus in Escherichia coli
NZ314777A (en) Vectors containing a gene for an antisigma polypeptide with a multiple cloning site
IT1189104B (it) Vettore plasmidico ad espressione in bacillus utile per il clonaggio del gene strutturale che codifica per l'ormone della crescita umano e procedimento per la produzione di detto ormone
WO2000053789A3 (de) Retrovirale expressionsvektoren auf der basis von herv-ltr-sequenzen
PT72787A (en) Methods for the preparation of improved vectors and for expressing cloned genes

Legal Events

Date Code Title Description
AHS Application shelved for other reasons than non-payment