DK384385A - Bicycliske forbindelser - Google Patents

Bicycliske forbindelser Download PDF

Info

Publication number: DK384385A
Authority: DK; Denmark
Prior art keywords: bicyclic; relations; bicyclic relations
Prior art date: 1984-08-24

Application number

DK384385A

Other languages

English (en)

Other versions

DK384385D0 (da

Inventor

Cedric Herbert Hassall

Geoffrey Lawton

Sally Redshaw

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-08-24

Filing date

1985-08-23

Publication date

1986-02-25

1984-08-24 Priority claimed from GB848421493A external-priority patent/GB8421493D0/en

1985-08-23 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

1985-08-23 Publication of DK384385D0 publication Critical patent/DK384385D0/da

1986-02-25 Publication of DK384385A publication Critical patent/DK384385A/da

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/04—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having less than three double bonds between ring members or between ring members and non-ring members

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Peptides Or Proteins (AREA)

DK384385A 1984-08-24 1985-08-23 Bicycliske forbindelser DK384385A (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB848421493A GB8421493D0 (en)	1984-08-24	1984-08-24	Bicyclic compounds
GB858513541A GB8513541D0 (en)	1984-08-24	1985-05-29	Bicyclic compounds

Publications (2)

Publication Number	Publication Date
DK384385D0 DK384385D0 (da)	1985-08-23
DK384385A true DK384385A (da)	1986-02-25

Family

ID=26288155

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK384385A DK384385A (da)	1984-08-24	1985-08-23	Bicycliske forbindelser

Country Status (14)

Country	Link
US (4)	US4692438A (da)
EP (1)	EP0172552A3 (da)
AU (1)	AU583843B2 (da)
CS (1)	CS255893B2 (da)
DK (1)	DK384385A (da)
ES (3)	ES8700258A1 (da)
FI (1)	FI853174L (da)
HU (1)	HU193446B (da)
IL (1)	IL76133A (da)
MC (1)	MC1694A1 (da)
NO (1)	NO161914C (da)
NZ (1)	NZ213130A (da)
PH (1)	PH21749A (da)
PT (1)	PT81015B (da)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4692438A (en) *	1984-08-24	1987-09-08	Hoffmann-La Roche Inc.	Pyridazo-diazepines, diazocines, and -triazepines having anti-hypertensive activity
ZW11586A1 (en) *	1985-07-01	1987-12-30	Hoffmann La Roche	Bicyclic compounds
GB8629875D0 (en) *	1986-12-15	1987-01-28	Hoffmann La Roche	Pyridazodiazepine derivatives
US5430145A (en) *	1990-10-18	1995-07-04	Merrell Dow Pharmaceuticals Inc.	Mercaptoacetylamide derivatives useful as inhibitors of enkephalinase and ace
US5308841A (en) *	1990-12-21	1994-05-03	Merrell Dow Pharmaceuticals Inc.	Amino and nitro containing tricyclic compounds useful as inhibitors of ACE
US5457196A (en) *	1991-09-27	1995-10-10	Merrell Dow Pharmaceuticals Inc.	2-substituted indane-2-carboxyalkyl derivatives useful as inhibitors of enkephalinase and ACE
US5455242A (en) *	1991-09-27	1995-10-03	Merrell Dow Pharmaceuticals Inc.	Carboxyalkyl tricyclic derivatives useful as inhibitors of enkephalinase and ace
CA2078758C (en) *	1991-09-27	2003-12-09	Alan M. Warshawsky	2-substituted indane-2-mercaptoacetylamide derivatives useful as inhibitors of enkephalinase and ace
DE69317764T2 (de) *	1992-02-14	1998-07-30	Merrell Pharmaceuticals Inc., Cincinnati, Ohio	Aminoacetylmercaptoacetylamid derivate mit enkephalinase- und ace-hemmwirkung
DK0640086T3 (da) *	1992-05-15	1999-12-06	Merrell Pharma Inc	Mercaptoacetylamido-pyridazo[1,2-a][1,2]diazepin-derivateranvendelige som enkephalinase- og ACE-inhibitorer
US5420271A (en) *	1992-08-24	1995-05-30	Merrell Dow Pharmaceuticals, Inc.	2-substituted indane-2-mercaptoacetylamide tricyclic derivatives useful as inhibitors of enkephalinase
PT669936E (pt) *	1992-10-30	2001-04-30	Merrell Pharma Inc	Derivados de lactama biciclica de mercaptoacetilamida uteis como inibidores de encefalinase e de ace
WO1994022440A1 (en) *	1993-03-29	1994-10-13	Smithkline Beecham Corporation	Bicyclic compounds which inhibit platelet aggregation
CA2183313C (en) *	1994-02-14	2001-01-02	Gary A. Flynn	Novel indane-2-mercaptoacetylamide disulfide derivatives useful as inhibitors of enkephalinase
US5530013A (en) *	1994-02-14	1996-06-25	American Home Products Corporation	Venlafaxine in the inducement of cognition enhancement
JPH09508906A (ja) *	1994-02-14	1997-09-09	メレルファーマスーティカルズインコーポレーテッド	エンケファリナーゼ及びａｃｅの阻害剤として有用な新規なメルカプトアセチルアミド１，３，４，５−テトラヒドロベンゾ［ｃ］アゼピン−３−オンジスルフィド誘導体類
WO1995021839A1 (en) *	1994-02-14	1995-08-17	Merrell Pharmaceuticals Inc.	Novel mercaptoacetylamide disulfide derivatives useful as inhibitors of enkephalinase and ace
CA2183314C (en) *	1994-02-14	1999-08-31	Gary A. Flynn	Novel 2-substituted indane-2-mercaptoacetylamide disulfide derivatives useful as inhibitors of enkephalinase and ace
US5484783A (en) *	1994-03-24	1996-01-16	Merrell Dow Pharmaceuticals Inc.	Hypocholesterolemic, antiatherosclerotic and hypotriglyceridemic mercaptoacetylamide and benzazapine derivatives
FI963784A0 (fi) *	1994-03-24	1996-09-23	Merrell Pharma Inc	Hypokolesteroleemisiä, antiateroskleroottisia ja hypotriglyserideemisiä merkaptoasetyyliamididisulfidijohdannaisia
NZ282568A (en) *	1994-03-24	1997-07-27	Merrell Pharma Inc	Use of condensed aminoacetylmercaptobenzazepines in treating elevated cholesterol levels, atherosclerosis, and hypotriglyceridemia
US6177565B1 (en) *	1998-08-19	2001-01-23	Vertex Pharmaceuticals Inc.	Process for synthesizing piperazic acid
US6703500B2 (en)	1998-08-19	2004-03-09	Vertex Pharmaceuticals, Incorporated	Method of preparing bicyclic intermediates from piperazic acid or an ester thereof useful in the manufacture of caspase inhibitors
US6559304B1 (en)	1998-08-19	2003-05-06	Vertex Pharmaceuticals Incorporated	Method for synthesizing caspase inhibitors
NZ520998A (en) *	2000-05-04	2004-11-26	Vertex Pharma	Asymmetric synthesis of piperazic acid and derivatives thereof
GB0119305D0 (en)	2001-04-12	2001-10-03	Aventis Pharma Gmbh	Mercaptoacetylamide derivatives,a process for their preparation and their use
US8408396B2 (en) *	2008-07-25	2013-04-02	Chuluun Enkhbold	Method of solid fuel beneficiation and transportation to thermoelectric power stations
WO2011073993A1 (en)	2009-12-16	2011-06-23	Hetero Research Foundation	Polymorphs of darunavir
PT2571355T (pt)	2010-05-20	2016-10-17	Hetero Research Foundation	Sal de cloridrato cristalino de darunavir

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4308094A (en) *	1977-02-02	1981-12-29	Sanyo Electric Co., Ltd.	Diaphragm for speaker and method of producing same
IL60617A0 (en) *	1979-07-23	1980-09-16	Sparamedica Ag	Triazolopyridazine derivative,their preparation and pharmaceutical compositions containing them
EP0025941B1 (de) *	1979-09-19	1983-05-04	F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft	Pyridazopyridazinderivate, Verfahren zu deren Herstellung und Arzneimittel enthaltend solche Pyridazopyridazinderivate
EP0042100A1 (de) *	1980-06-13	1981-12-23	F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft	Pyrazolopyridazin-Derivate, Zwischenprodukte und Verfahren zu deren Herstellung, sowie diese enthaltende Arzneimittel
GB2128984B (en) *	1982-05-12	1985-05-22	Hoffmann La Roche	Diaza-bicyclic compounds
US4692438A (en) *	1984-08-24	1987-09-08	Hoffmann-La Roche Inc.	Pyridazo-diazepines, diazocines, and -triazepines having anti-hypertensive activity

1985
- 1985-08-12 US US06/764,372 patent/US4692438A/en not_active Expired - Fee Related
- 1985-08-15 CS CS855928A patent/CS255893B2/cs unknown
- 1985-08-16 NZ NZ213130A patent/NZ213130A/en unknown
- 1985-08-19 EP EP85110370A patent/EP0172552A3/de not_active Withdrawn
- 1985-08-19 FI FI853174A patent/FI853174L/fi not_active Application Discontinuation
- 1985-08-19 IL IL76133A patent/IL76133A/xx unknown
- 1985-08-19 AU AU46415/85A patent/AU583843B2/en not_active Ceased
- 1985-08-21 PH PH32671A patent/PH21749A/en unknown
- 1985-08-21 MC MC851791A patent/MC1694A1/fr unknown
- 1985-08-21 HU HU853187A patent/HU193446B/hu not_active IP Right Cessation
- 1985-08-23 NO NO853336A patent/NO161914C/no unknown
- 1985-08-23 ES ES546360A patent/ES8700258A1/es not_active Expired
- 1985-08-23 DK DK384385A patent/DK384385A/da not_active Application Discontinuation
- 1985-08-23 PT PT81015A patent/PT81015B/pt unknown
1986
- 1986-02-17 ES ES552397A patent/ES8705443A1/es not_active Expired
- 1986-02-17 ES ES552398A patent/ES8705444A1/es not_active Expired
1987
- 1987-05-11 US US07/048,172 patent/US4785093A/en not_active Expired - Fee Related
- 1987-06-15 US US07/062,033 patent/US4762924A/en not_active Expired - Fee Related
1988
- 1988-07-12 US US07/217,805 patent/US4826980A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
DK384385D0 (da)	1985-08-23
US4785093A (en)	1988-11-15
PT81015B (en)	1987-08-24
NO161914C (no)	1989-10-11
US4692438A (en)	1987-09-08
ES552397A0 (es)	1987-05-01
US4826980A (en)	1989-05-02
PH21749A (en)	1988-02-18
EP0172552A2 (de)	1986-02-26
CS255893B2 (en)	1988-03-15
NO853336L (no)	1986-02-25
IL76133A (en)	1989-12-15
HU193446B (en)	1987-10-28
NO161914B (no)	1989-07-03
FI853174A7 (fi)	1986-02-25
US4762924A (en)	1988-08-09
ES8705444A1 (es)	1987-05-01
CS592885A2 (en)	1987-07-16
AU583843B2 (en)	1989-05-11
MC1694A1 (fr)	1986-07-18
FI853174L (fi)	1986-02-25
PT81015A (en)	1985-09-01
IL76133A0 (en)	1985-12-31
FI853174A0 (fi)	1985-08-19
ES546360A0 (es)	1986-10-01
EP0172552A3 (de)	1989-01-11
HUT38644A (en)	1986-06-30
ES8700258A1 (es)	1986-10-01
ES552398A0 (es)	1987-05-01
AU4641585A (en)	1986-02-27
ES8705443A1 (es)	1987-05-01
NZ213130A (en)	1988-05-30

Legal Events

Date	Code	Title	Description
1991-04-22	AHB	Application shelved due to non-payment

Publication	Publication Date	Title
DK384385D0 (da)	1985-08-23	Bicycliske forbindelser
DK499485D0 (da)	1985-10-30	Forbindelser
DK424685D0 (da)	1985-09-18	Forbindelser
AT380762B (de)	1986-07-10	Hoergeraet
AT379929B (de)	1986-03-10	Hoergeraet
DK155985A (da)	1985-10-10	Cephem-derivater
DK1585D0 (da)	1985-01-02	Cephalosporinantibiotica
ATA98284A (de)	1991-06-15	Schalplatte
ATA135485A (de)	1990-07-15	Maishaecksler
SE455355B (sv)	1988-07-04	Tryckstromstellare
DK284486A (da)	1986-12-20	Bicycliske forbindelser
DK297386A (da)	1987-01-02	Bicycliske forbindelser
BR8505778A (pt)	1986-08-12	Dentifricio adstringente
ATA45484A (de)	1985-05-15	Kimme
ATA906584A (de)	1989-04-15	Elektrokoagulator
BR8402733A (pt)	1986-01-07	Divisoria
NO862632D0 (no)	1986-06-30	Bicykliske forbindelser.
DK521885D0 (da)	1985-11-12	Saerlig fremgangsmaade
ES280124Y (es)	1985-06-16	Conjunto de tapon-precinto
AR231237A1 (es)	1984-10-31	Calzado-patin
BR8401156A (pt)	1985-10-29	Auto-balsa
BR8400417A (pt)	1985-09-03	Moto-continuo magnetico
BR6401784U (pt)	1986-06-03	Trimino
BR8404566A (pt)	1986-04-15	Paramortecedor
BR8400991A (pt)	1985-03-19	Forcapassivativa