DK3886813T3 - Farmaceutiske formuleringer af cyclosporinanaloger - Google Patents
Farmaceutiske formuleringer af cyclosporinanaloger Download PDFInfo
- Publication number
- DK3886813T3 DK3886813T3 DK19821392.8T DK19821392T DK3886813T3 DK 3886813 T3 DK3886813 T3 DK 3886813T3 DK 19821392 T DK19821392 T DK 19821392T DK 3886813 T3 DK3886813 T3 DK 3886813T3
- Authority
- DK
- Denmark
- Prior art keywords
- pharmaceutical formulations
- cyclosporine analogs
- cyclosporine
- analogs
- formulations
- Prior art date
Links
- PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical class CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Dispersion Chemistry (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Communicable Diseases (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862771453P | 2018-11-26 | 2018-11-26 | |
| PCT/US2019/062849 WO2020112562A1 (en) | 2018-11-26 | 2019-11-22 | Pharmaceutical formulations of cyclosporine analogs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3886813T3 true DK3886813T3 (da) | 2023-05-01 |
Family
ID=68916602
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK19821392.8T DK3886813T3 (da) | 2018-11-26 | 2019-11-22 | Farmaceutiske formuleringer af cyclosporinanaloger |
Country Status (28)
| Country | Link |
|---|---|
| US (3) | US20200163876A1 (da) |
| EP (1) | EP3886813B1 (da) |
| JP (1) | JP7489385B2 (da) |
| KR (1) | KR20210099038A (da) |
| CN (1) | CN113194927B (da) |
| AR (1) | AR117150A1 (da) |
| AU (1) | AU2019386859A1 (da) |
| BR (1) | BR112021009967A2 (da) |
| CA (1) | CA3120015A1 (da) |
| CY (1) | CY1126071T1 (da) |
| DK (1) | DK3886813T3 (da) |
| ES (1) | ES2942473T3 (da) |
| FI (1) | FI3886813T3 (da) |
| HR (1) | HRP20230548T1 (da) |
| HU (1) | HUE061877T2 (da) |
| IL (1) | IL283286A (da) |
| LT (1) | LT3886813T (da) |
| MX (1) | MX2021006010A (da) |
| PH (1) | PH12021551086A1 (da) |
| PL (1) | PL3886813T3 (da) |
| PT (1) | PT3886813T (da) |
| RS (1) | RS64239B1 (da) |
| SG (1) | SG11202105336TA (da) |
| SI (1) | SI3886813T1 (da) |
| SM (1) | SMT202300139T1 (da) |
| TW (1) | TWI844585B (da) |
| WO (1) | WO2020112562A1 (da) |
| ZA (1) | ZA202103090B (da) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3171882A1 (en) | 2020-02-19 | 2021-08-26 | Hepion Pharmaceuticals, Inc. | Use of cyclosporine analogues for treating fibrosis |
| AU2021227230A1 (en) | 2020-02-25 | 2022-09-08 | Hepion Pharmaceuticals, Inc. | Use of cyclosporine analogues for treating cancer |
| CA3199530A1 (en) * | 2020-11-29 | 2022-06-02 | Hepion Pharmaceuticals, Inc. | Use of cyclosporine analogues as antithrombotic agents |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR0148748B1 (ko) * | 1988-09-16 | 1998-08-17 | 장 크라메르, 한스 루돌프 하우스 | 사이클로스포린을 함유하는 약학조성물 |
| US6262022B1 (en) * | 1992-06-25 | 2001-07-17 | Novartis Ag | Pharmaceutical compositions containing cyclosporin as the active agent |
| GB9113872D0 (en) * | 1991-06-27 | 1991-08-14 | Sandoz Ag | Improvements in or relating to organic compounds |
| WO1999029316A1 (en) * | 1997-12-10 | 1999-06-17 | Severson, Mary, L. | Pharmaceutical compositions containing an omega-3 fatty acid oil |
| US20030216303A1 (en) * | 1998-03-06 | 2003-11-20 | Michael Ambuhl | Emulsion preconcentrates containing cyclosporin or a macrolide |
| ID25908A (id) * | 1998-03-06 | 2000-11-09 | Novartis Ag | Prakonsentrat-prakonsentrat emulsi yang mengandung siklosporin atau makrolida |
| WO2001028518A1 (de) * | 1999-10-20 | 2001-04-26 | Vesifact Ag | Cyclosporine enthaltende mikroemulsion-prekonzentrate und mikroemulsionen |
| EA200301139A1 (ru) * | 2001-06-21 | 2004-12-30 | Пфайзер Продактс Инк. | Самоэмульгирующиеся препараты ингибиторов белка-переносчика эфиров холестерина |
| IL160761A0 (en) * | 2001-10-19 | 2004-08-31 | Isotechnika Inc | Novel cyclosporin analog microemulsion preconcentrates |
| US20180296588A1 (en) * | 2017-04-14 | 2018-10-18 | Contravir Pharmaceuticals, Inc. | Combination therapy for treating viral infections |
-
2019
- 2019-11-22 FI FIEP19821392.8T patent/FI3886813T3/fi active
- 2019-11-22 AR ARP190103428A patent/AR117150A1/es not_active Application Discontinuation
- 2019-11-22 LT LTEPPCT/US2019/062849T patent/LT3886813T/lt unknown
- 2019-11-22 JP JP2021529703A patent/JP7489385B2/ja active Active
- 2019-11-22 TW TW108142503A patent/TWI844585B/zh active
- 2019-11-22 MX MX2021006010A patent/MX2021006010A/es unknown
- 2019-11-22 CN CN201980077553.8A patent/CN113194927B/zh active Active
- 2019-11-22 WO PCT/US2019/062849 patent/WO2020112562A1/en not_active Ceased
- 2019-11-22 CA CA3120015A patent/CA3120015A1/en active Pending
- 2019-11-22 KR KR1020217019811A patent/KR20210099038A/ko not_active Ceased
- 2019-11-22 AU AU2019386859A patent/AU2019386859A1/en not_active Abandoned
- 2019-11-22 RS RS20230417A patent/RS64239B1/sr unknown
- 2019-11-22 BR BR112021009967-0A patent/BR112021009967A2/pt not_active IP Right Cessation
- 2019-11-22 PL PL19821392.8T patent/PL3886813T3/pl unknown
- 2019-11-22 SM SM20230139T patent/SMT202300139T1/it unknown
- 2019-11-22 ES ES19821392T patent/ES2942473T3/es active Active
- 2019-11-22 HR HRP20230548TT patent/HRP20230548T1/hr unknown
- 2019-11-22 EP EP19821392.8A patent/EP3886813B1/en active Active
- 2019-11-22 SG SG11202105336TA patent/SG11202105336TA/en unknown
- 2019-11-22 US US16/693,051 patent/US20200163876A1/en not_active Abandoned
- 2019-11-22 PT PT198213928T patent/PT3886813T/pt unknown
- 2019-11-22 HU HUE19821392A patent/HUE061877T2/hu unknown
- 2019-11-22 DK DK19821392.8T patent/DK3886813T3/da active
- 2019-11-22 SI SI201930510T patent/SI3886813T1/sl unknown
-
2021
- 2021-05-07 PH PH12021551086A patent/PH12021551086A1/en unknown
- 2021-05-07 ZA ZA2021/03090A patent/ZA202103090B/en unknown
- 2021-05-19 IL IL283286A patent/IL283286A/en unknown
-
2023
- 2023-06-22 CY CY20231100293T patent/CY1126071T1/el unknown
- 2023-08-17 US US18/451,456 patent/US20230390198A1/en not_active Abandoned
- 2023-08-17 US US18/451,467 patent/US20230390199A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP3886813A1 (en) | 2021-10-06 |
| PL3886813T3 (pl) | 2023-06-19 |
| ES2942473T3 (es) | 2023-06-01 |
| CN113194927B (zh) | 2023-10-27 |
| CA3120015A1 (en) | 2020-06-04 |
| EP3886813B1 (en) | 2023-03-22 |
| LT3886813T (lt) | 2023-04-11 |
| WO2020112562A1 (en) | 2020-06-04 |
| CN113194927A (zh) | 2021-07-30 |
| BR112021009967A2 (pt) | 2021-08-17 |
| US20230390199A1 (en) | 2023-12-07 |
| SMT202300139T1 (it) | 2023-07-20 |
| PH12021551086A1 (en) | 2022-01-03 |
| IL283286A (en) | 2021-07-29 |
| AU2019386859A1 (en) | 2021-05-27 |
| SI3886813T1 (sl) | 2023-05-31 |
| JP7489385B2 (ja) | 2024-05-23 |
| KR20210099038A (ko) | 2021-08-11 |
| HUE061877T2 (hu) | 2023-08-28 |
| MX2021006010A (es) | 2021-09-21 |
| ZA202103090B (en) | 2023-09-27 |
| PT3886813T (pt) | 2023-04-26 |
| CY1126071T1 (el) | 2023-11-15 |
| JP2022513635A (ja) | 2022-02-09 |
| AR117150A1 (es) | 2021-07-14 |
| RS64239B1 (sr) | 2023-06-30 |
| FI3886813T3 (fi) | 2023-05-04 |
| US20200163876A1 (en) | 2020-05-28 |
| HRP20230548T1 (hr) | 2023-08-04 |
| US20230390198A1 (en) | 2023-12-07 |
| TW202038911A (zh) | 2020-11-01 |
| SG11202105336TA (en) | 2021-06-29 |
| TWI844585B (zh) | 2024-06-11 |
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