DK393488A - N-((2-oxopyrrolidin-1-yl)acetyl)piperazinderivater og farmaceutisk praeparat mod senil demens - Google Patents
N-((2-oxopyrrolidin-1-yl)acetyl)piperazinderivater og farmaceutisk praeparat mod senil demensInfo
- Publication number
- DK393488A DK393488A DK393488A DK393488A DK393488A DK 393488 A DK393488 A DK 393488A DK 393488 A DK393488 A DK 393488A DK 393488 A DK393488 A DK 393488A DK 393488 A DK393488 A DK 393488A
- Authority
- DK
- Denmark
- Prior art keywords
- demens
- senil
- oxopyrrolidin
- acetyl
- pharmaceutical preparations
- Prior art date
Links
- YFXAZRCWZHAOHD-UHFFFAOYSA-N 1-(2-oxo-2-piperazin-1-ylethyl)pyrrolidin-2-one Chemical class C1CNCCN1C(=O)CN1CCCC1=O YFXAZRCWZHAOHD-UHFFFAOYSA-N 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 125000006527 (C1-C5) alkyl group Chemical group 0.000 abstract 2
- -1 C8-C12 phenylalkenyl Chemical group 0.000 abstract 2
- 125000002373 5 membered heterocyclic group Chemical group 0.000 abstract 1
- 125000004070 6 membered heterocyclic group Chemical group 0.000 abstract 1
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 206010039966 Senile dementia Diseases 0.000 abstract 1
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 230000000506 psychotropic effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
- C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02C—CAPTURE, STORAGE, SEQUESTRATION OR DISPOSAL OF GREENHOUSE GASES [GHG]
- Y02C20/00—Capture or disposal of greenhouse gases
- Y02C20/40—Capture or disposal of greenhouse gases of CO2
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP17806487 | 1987-07-15 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK393488D0 DK393488D0 (da) | 1988-07-14 |
| DK393488A true DK393488A (da) | 1989-01-16 |
Family
ID=16041980
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK393488A DK393488A (da) | 1987-07-15 | 1988-07-14 | N-((2-oxopyrrolidin-1-yl)acetyl)piperazinderivater og farmaceutisk praeparat mod senil demens |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US4904663A (da) |
| EP (1) | EP0299493B1 (da) |
| KR (1) | KR900006742B1 (da) |
| AT (1) | ATE106868T1 (da) |
| AU (1) | AU608025B2 (da) |
| CA (1) | CA1322199C (da) |
| DE (1) | DE3889987T2 (da) |
| DK (1) | DK393488A (da) |
| ES (1) | ES2056860T3 (da) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1231477B (it) * | 1989-07-12 | 1991-12-07 | Sigma Tau Ind Farmaceuti | (pirrolidin-2-one-1-il) acetammidi quali attivatori dei processi di apprendimento e della memoria e composizioni farmaceutiche comprendenti tali composti |
| US5250528A (en) * | 1989-08-02 | 1993-10-05 | Fujisawa Pharmaceutical Co., Ltd. | New aminopiperazine derivatives |
| IT1243702B (it) * | 1990-08-08 | 1994-06-21 | Pulitzer Italiana | Composti ad attivita' nootropa, procedimento per la loro preparazione e relative composizioni farmaceutiche |
| US6359134B1 (en) | 1997-05-30 | 2002-03-19 | Takeda Chemical Industries, Ltd. | Sulfonamide derivatives, their production and use |
| CN1290254A (zh) | 1998-02-05 | 2001-04-04 | 武田药品工业株式会社 | 氨磺酰衍生物及其制备和用途 |
| AUPP818099A0 (en) * | 1999-01-14 | 1999-02-11 | Fujisawa Pharmaceutical Co., Ltd. | New n-containing heterocyclic compounds |
| US6538017B2 (en) | 2001-03-09 | 2003-03-25 | Ortho-Mcneil Pharmaceutical, Inc. | Aminopyrrolidine sulfonamides as serine protease inhibitors |
| US6710061B2 (en) | 2001-03-09 | 2004-03-23 | Ortho-Mcneil Pharamceutical, Inc. | Aminopyrrolidine sulfonamides as serine protease inhibitors |
| CA2450073C (en) | 2001-07-25 | 2017-08-29 | Biomarin Pharmaceutical Inc. | Compositions and methods for modulating blood-brain barrier transport |
| EP2671508B1 (en) | 2005-04-28 | 2020-09-16 | Proteus Digital Health, Inc. | Pharma-informatics system |
| JP2010503710A (ja) | 2006-09-18 | 2010-02-04 | ラプトール ファーマシューティカル インコーポレイテッド | 受容体関連タンパク質（ｒａｐ）結合体の投与による肝障害の処置 |
| ES2919563T3 (es) | 2009-02-20 | 2022-07-27 | Enhanx Biopharm Inc | Sistema de administración de medicamentos a base de glutatión |
| KR20180114970A (ko) | 2009-05-06 | 2018-10-19 | 라보라토리 스킨 케어, 인크. | 활성제-칼슘 포스페이트 입자 복합체를 포함하는 피부 전달 조성물 및 이들을 이용하는 방법 |
| US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE864269A (fr) * | 1977-03-03 | 1978-06-16 | Parke Davis & Co | Nouveaux n-(aminoalkyl substitue)-2-oxo-1-pyrrolidine-acetamides et procedes pour les produire |
| ATE27T1 (de) * | 1978-05-08 | 1981-04-15 | Ucb Sa | Lactam-n-essigsaeuren und ihre amide, verfahren zu ihrer herstellung und heilmittel, die sie enthalten |
| US4372960A (en) * | 1980-12-12 | 1983-02-08 | Warner-Lambert Company | Quaternary derivatives of N-(substituted-aminoalkyl)-2-oxo-1-pyrrolidine-acetamides as cognition activators |
| FR2515179A1 (fr) * | 1981-07-24 | 1983-04-29 | Hoffmann La Roche | Derives de pyrrolidine, leur procede de preparation, les intermediaires pour leur synthese et leur application therapeutique |
| DE3361609D1 (en) * | 1982-03-24 | 1986-02-06 | Prodes Sa | New n-((2-oxo-1-pyrrolidinyl)acetyl)piperazines, the methods of producing such new compounds and their salts as well as pharmaceutical preparations for therapeutic use containing these compounds or salts |
| US4668687A (en) * | 1984-07-23 | 1987-05-26 | Bristol-Myers Company | Psychogeriatric 1-(2-pyrimidinyl)piperazinyl derivatives of 1-pyrrolidin-2-ones |
| CA1250291A (en) * | 1984-07-23 | 1989-02-21 | Bristol-Myers Company | Psychogeriatric 1-(2-pyrimidinyl)-piperazinyl derivatives of 1-pyrrolidin-2-ones |
| GB8512163D0 (en) * | 1985-05-14 | 1985-06-19 | Fujisawa Pharmaceutical Co | Oxothiazolidine compound |
-
1988
- 1988-07-06 CA CA000571320A patent/CA1322199C/en not_active Expired - Fee Related
- 1988-07-13 AU AU19013/88A patent/AU608025B2/en not_active Ceased
- 1988-07-14 ES ES88111353T patent/ES2056860T3/es not_active Expired - Lifetime
- 1988-07-14 DE DE3889987T patent/DE3889987T2/de not_active Expired - Fee Related
- 1988-07-14 EP EP88111353A patent/EP0299493B1/en not_active Expired - Lifetime
- 1988-07-14 AT AT88111353T patent/ATE106868T1/de not_active IP Right Cessation
- 1988-07-14 DK DK393488A patent/DK393488A/da not_active Application Discontinuation
- 1988-07-15 US US07/221,450 patent/US4904663A/en not_active Expired - Fee Related
- 1988-07-15 KR KR1019880008858A patent/KR900006742B1/ko not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| AU608025B2 (en) | 1991-03-21 |
| CA1322199C (en) | 1993-09-14 |
| ATE106868T1 (de) | 1994-06-15 |
| DE3889987D1 (de) | 1994-07-14 |
| KR900006742B1 (ko) | 1990-09-20 |
| AU1901388A (en) | 1989-01-19 |
| DE3889987T2 (de) | 1994-09-15 |
| EP0299493A2 (en) | 1989-01-18 |
| US4904663A (en) | 1990-02-27 |
| DK393488D0 (da) | 1988-07-14 |
| EP0299493A3 (en) | 1990-05-23 |
| KR890002097A (ko) | 1989-04-07 |
| ES2056860T3 (es) | 1994-10-16 |
| EP0299493B1 (en) | 1994-06-08 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX9306831A (es) | Nuevos compuestos heterociclicos. | |
| PT88410A (pt) | Process for preparing thiazolidinedione derivatives | |
| DK393488D0 (da) | N-((2-oxopyrrolidin-1-yl)acetyl)piperazinderivater og farmaceutisk praeparat mod senil demens | |
| DK0389282T3 (da) | Xanthinderivater, fremgangsmåde til deres fremstilling og deres farmaceutiske anvendelse | |
| DZ1694A1 (fr) | "n-(2-Aminoethyl)-benzothialozones". | |
| DK5386A (da) | Arylcyklobutylaminer og laegemiddelpraeparat indeholdende en saadan forbindelse | |
| FI894693A0 (fi) | Menetelmä valmistaa farmaseuttisesti arvokasta imidatsoliinijohdannaista | |
| TW249804B (da) | ||
| FR2612517B1 (fr) | Derives de benzoxazine, procedes de preparation de ces derives et compositions pharmaceutiques les contenant | |
| TW221429B (da) | ||
| DK148288A (da) | N-phenethylaminoalkyl-benzamid-forbindelser, deres anvendelse til fremstilling af antiarrhythmia-laegemidler og farmaceutiske praeparater indeholdende forbindelserne | |
| DE69110217D1 (de) | Derivate der Kaffeinsäure und sie enthaltende pharmazeutische Zusammensetzungen. | |
| HUT43068A (en) | Process for preparing 5-amino-alkyl-beta-carboline derivatives and pharmaceutical compositions containing them | |
| NO174886C (no) | Analogifremgangsmåte for fremstilling av terapeutisk aktive pyrrolidin-derivater | |
| DK614989D0 (da) | Indolderivater, fremgangsmaade til deres fremstilling og farmaceutiske midler indeholdende dem | |
| NO903084D0 (no) | Farmasoeytisk anvendbare thiazol-derivater og fremgangsmaate for deres fremstilling. | |
| DK424888D0 (da) | Naphthothiazepinderivater, fremgangsmaade til fremstilling deraf samt farmaceutiske praeparater indeholdende saadanne derivater | |
| DK0850939T3 (da) | Ellipticin-derivater, fremgangsmåde til fremstilling deraf og farmaceutiske sammensætninger indeholdende derivaterne |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHB | Application shelved due to non-payment |