DK404982A - Fremgangsmaade til fremstilling af substituerede pyrimid-2-oner eller salte deraf - Google Patents
Fremgangsmaade til fremstilling af substituerede pyrimid-2-oner eller salte deraf Download PDFInfo
- Publication number
- DK404982A DK404982A DK404982A DK404982A DK404982A DK 404982 A DK404982 A DK 404982A DK 404982 A DK404982 A DK 404982A DK 404982 A DK404982 A DK 404982A DK 404982 A DK404982 A DK 404982A
- Authority
- DK
- Denmark
- Prior art keywords
- group
- aliphatic group
- saturated
- compounds
- trifluoromethyl
- Prior art date
Links
- 125000001931 aliphatic group Chemical group 0.000 abstract 3
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000000623 heterocyclic group Chemical group 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 229920006395 saturated elastomer Polymers 0.000 abstract 2
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
- KUAWDIFZEBBSPW-UHFFFAOYSA-N 5-(trifluoromethyl)-1h-pyrimidin-2-one Chemical compound OC1=NC=C(C(F)(F)F)C=N1 KUAWDIFZEBBSPW-UHFFFAOYSA-N 0.000 abstract 1
- 230000002159 abnormal effect Effects 0.000 abstract 1
- 230000002378 acidificating effect Effects 0.000 abstract 1
- 125000002015 acyclic group Chemical group 0.000 abstract 1
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000002837 carbocyclic group Chemical group 0.000 abstract 1
- 230000004663 cell proliferation Effects 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- -1 hydroxy, mercapto Chemical class 0.000 abstract 1
- 239000012948 isocyanate Substances 0.000 abstract 1
- 150000002513 isocyanates Chemical class 0.000 abstract 1
- 125000004043 oxo group Chemical group O=* 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/34—One oxygen atom
- C07D239/36—One oxygen atom as doubly bound oxygen atom or as unsubstituted hydroxy radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Saccharide Compounds (AREA)
- Pyrrole Compounds (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8127505 | 1981-09-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK404982A true DK404982A (da) | 1983-03-12 |
Family
ID=10524445
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK404982A DK404982A (da) | 1981-09-11 | 1982-09-10 | Fremgangsmaade til fremstilling af substituerede pyrimid-2-oner eller salte deraf |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US4478839A (da) |
| EP (1) | EP0074820B1 (da) |
| JP (1) | JPS5857368A (da) |
| AT (1) | ATE21693T1 (da) |
| AU (1) | AU8818882A (da) |
| DE (1) | DE3272892D1 (da) |
| DK (1) | DK404982A (da) |
| ES (1) | ES515640A0 (da) |
| NO (1) | NO823075L (da) |
| NZ (1) | NZ201883A (da) |
| ZA (1) | ZA826660B (da) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58159479A (ja) * | 1982-02-24 | 1983-09-21 | ニユエガ−ド・アンド・コンパニ−・アクシエ／セルカペト | 置換されたピリミジン−２−オン化合物 |
| JPH0613535B2 (ja) * | 1984-09-10 | 1994-02-23 | 株式会社三和化学研究所 | 新規な有機珪素化合物、その製法並びに該化合物を有効成分とする抗腫瘍剤 |
| US4675321A (en) * | 1986-02-07 | 1987-06-23 | Merck & Co., Inc. | Substituted pyrimidines useful as calcium channel blockers |
| JP2873340B2 (ja) * | 1988-04-29 | 1999-03-24 | 武田薬品工業株式会社 | 抗生物質ｔａｎ―１０５７，その製造法および用途 |
| US8679231B2 (en) | 2011-01-19 | 2014-03-25 | Advanced Technology Materials, Inc. | PVDF pyrolyzate adsorbent and gas storage and dispensing system utilizing same |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1561290A (en) * | 1975-10-16 | 1980-02-20 | Nyegaard & Co As | Pyrimid - 2 - ones |
| US4052400A (en) * | 1976-10-29 | 1977-10-04 | Morton-Norwich Products, Inc. | Hypertensive 1-substituted 2(1h)-pyrimidones |
-
1982
- 1982-09-10 NO NO823075A patent/NO823075L/no unknown
- 1982-09-10 ES ES515640A patent/ES515640A0/es active Granted
- 1982-09-10 EP EP82304780A patent/EP0074820B1/en not_active Expired
- 1982-09-10 JP JP57156882A patent/JPS5857368A/ja active Pending
- 1982-09-10 ZA ZA826660A patent/ZA826660B/xx unknown
- 1982-09-10 DK DK404982A patent/DK404982A/da not_active Application Discontinuation
- 1982-09-10 NZ NZ201883A patent/NZ201883A/en unknown
- 1982-09-10 DE DE8282304780T patent/DE3272892D1/de not_active Expired
- 1982-09-10 US US06/416,670 patent/US4478839A/en not_active Expired - Fee Related
- 1982-09-10 AT AT82304780T patent/ATE21693T1/de active
- 1982-09-10 AU AU88188/82A patent/AU8818882A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| ZA826660B (en) | 1983-08-31 |
| US4478839A (en) | 1984-10-23 |
| DE3272892D1 (en) | 1986-10-02 |
| NO823075L (no) | 1983-03-14 |
| AU8818882A (en) | 1983-03-17 |
| JPS5857368A (ja) | 1983-04-05 |
| ES8308860A1 (es) | 1983-10-01 |
| ATE21693T1 (de) | 1986-09-15 |
| EP0074820A1 (en) | 1983-03-23 |
| NZ201883A (en) | 1985-11-08 |
| EP0074820B1 (en) | 1986-08-27 |
| ES515640A0 (es) | 1983-10-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ATS | Application withdrawn |