DK4076652T3 - Farmaceutisk acceptabelt atrasentansalt til anvendelse i en fremgangsmåde til behandling af iga-nefropati - Google Patents

Farmaceutisk acceptabelt atrasentansalt til anvendelse i en fremgangsmåde til behandling af iga-nefropati

Info

Publication number
DK4076652T3
DK4076652T3 DK20903533.6T DK20903533T DK4076652T3 DK 4076652 T3 DK4076652 T3 DK 4076652T3 DK 20903533 T DK20903533 T DK 20903533T DK 4076652 T3 DK4076652 T3 DK 4076652T3
Authority
DK
Denmark
Prior art keywords
atrasentan
salt
pharmaceutically acceptable
iga nephropathy
treating iga
Prior art date
Application number
DK20903533.6T
Other languages
English (en)
Inventor
Philip Thomas Frohlich
Andrew James King
Chidambaram Ramachandran
Sarah Beth Noonberg
Original Assignee
Chinook Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinook Therapeutics Inc filed Critical Chinook Therapeutics Inc
Application granted granted Critical
Publication of DK4076652T3 publication Critical patent/DK4076652T3/da

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/12Antidiuretics, e.g. drugs for diabetes insipidus
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/472Non-condensed isoquinolines, e.g. papaverine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
DK20903533.6T 2019-12-17 2020-12-16 Farmaceutisk acceptabelt atrasentansalt til anvendelse i en fremgangsmåde til behandling af iga-nefropati DK4076652T3 (da)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201962949115P 2019-12-17 2019-12-17
US202063005003P 2020-04-03 2020-04-03
US202063072699P 2020-08-31 2020-08-31
US202063084739P 2020-09-29 2020-09-29
US202063125205P 2020-12-14 2020-12-14
PCT/US2020/065311 WO2021126977A1 (en) 2019-12-17 2020-12-16 Methods of treating iga nephropathy with atrasentan

Publications (1)

Publication Number Publication Date
DK4076652T3 true DK4076652T3 (da) 2026-03-02

Family

ID=76478538

Family Applications (1)

Application Number Title Priority Date Filing Date
DK20903533.6T DK4076652T3 (da) 2019-12-17 2020-12-16 Farmaceutisk acceptabelt atrasentansalt til anvendelse i en fremgangsmåde til behandling af iga-nefropati

Country Status (21)

Country Link
US (11) US20210353593A1 (da)
EP (2) EP4076652B1 (da)
JP (2) JP7624995B2 (da)
KR (1) KR20230015874A (da)
CN (3) CN116327758A (da)
AU (1) AU2020404984A1 (da)
BR (1) BR112022012075A2 (da)
CA (1) CA3161516A1 (da)
DK (1) DK4076652T3 (da)
FI (1) FI4076652T3 (da)
HR (1) HRP20260121T1 (da)
IL (1) IL293921A (da)
LT (1) LT4076652T (da)
MX (1) MX2022007471A (da)
PH (1) PH12022551456A1 (da)
PL (1) PL4076652T3 (da)
PT (1) PT4076652T (da)
RS (1) RS67746B1 (da)
SI (1) SI4076652T1 (da)
TW (2) TWI914232B (da)
WO (1) WO2021126977A1 (da)

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CN114910647A (zh) * 2022-05-07 2022-08-16 浙江大学 细丝蛋白-A-IgG抗体在制备检测血管内皮损伤试剂盒中的应用
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WO2024073672A1 (en) 2022-09-30 2024-04-04 Travere Therapeutics, Inc. Combination therapy with sparsentan and a sglt2 inhibitor for treating kidney diseases or disorders
JP2025533903A (ja) * 2022-10-05 2025-10-09 デーウン ファーマシューティカル カンパニー リミテッド エナボグリフロジンを含む腎障害及び/又は糖尿病の予防又は治療用薬学組成物{pharmaceutical composition for prevention or treatment of nephropathy and/or diabetes mellitus, comprising enavogliflozin}
EP4608396A1 (en) * 2022-10-28 2025-09-03 Chinook Therapeutics, Inc. Treatment of iga nephropathy using an endothelin receptor antagonist and an april binding antibody
KR20250090355A (ko) 2022-11-07 2025-06-19 산레노 테라퓨틱스 (상하이) 리미티드 Iga 신병증 치료를 위한 엔도텔린 수용체 길항제 및 글루코코르티코이드의 조합
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Also Published As

Publication number Publication date
US11491137B2 (en) 2022-11-08
TW202130350A (zh) 2021-08-16
LT4076652T (lt) 2026-02-25
EP4076652A1 (en) 2022-10-26
US20230355580A1 (en) 2023-11-09
US20230129646A1 (en) 2023-04-27
US12370174B2 (en) 2025-07-29
PT4076652T (pt) 2026-02-12
US20220288026A1 (en) 2022-09-15
TWI914232B (zh) 2026-02-01
US11998526B2 (en) 2024-06-04
US20210353593A1 (en) 2021-11-18
WO2021126977A1 (en) 2021-06-24
US20240108599A1 (en) 2024-04-04
FI4076652T3 (fi) 2026-02-10
CN116327758A (zh) 2023-06-27
US12521369B2 (en) 2026-01-13
JP7821870B2 (ja) 2026-02-27
JP2023507739A (ja) 2023-02-27
SI4076652T1 (sl) 2026-03-31
HRP20260121T1 (hr) 2026-03-13
AU2020404984A1 (en) 2022-07-14
US20230355579A1 (en) 2023-11-09
TWI875895B (zh) 2025-03-11
US20250281454A1 (en) 2025-09-11
CN113272013A (zh) 2021-08-17
US20230364055A1 (en) 2023-11-16
US12582631B2 (en) 2026-03-24
EP4710928A3 (en) 2026-04-15
PH12022551456A1 (en) 2023-10-23
EP4076652B1 (en) 2025-12-03
JP2025060686A (ja) 2025-04-10
EP4076652A4 (en) 2024-01-03
WO2021126977A9 (en) 2021-07-22
BR112022012075A2 (pt) 2022-08-30
RS67746B1 (sr) 2026-03-31
TW202545517A (zh) 2025-12-01
US20220288027A1 (en) 2022-09-15
CN116173014A (zh) 2023-05-30
US20220304978A1 (en) 2022-09-29
JP7624995B2 (ja) 2025-01-31
US20250120945A1 (en) 2025-04-17
KR20230015874A (ko) 2023-01-31
PL4076652T3 (pl) 2026-03-23
US12121509B2 (en) 2024-10-22
EP4710928A2 (en) 2026-03-18
IL293921A (en) 2022-08-01
CA3161516A1 (en) 2021-06-24
MX2022007471A (es) 2022-08-17

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