DK4132943T3 - Immunoglobulin-bindende proteiner til affinitetsoprensning - Google Patents

Immunoglobulin-bindende proteiner til affinitetsoprensning Download PDF

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Publication number
DK4132943T3
DK4132943T3 DK21736946.1T DK21736946T DK4132943T3 DK 4132943 T3 DK4132943 T3 DK 4132943T3 DK 21736946 T DK21736946 T DK 21736946T DK 4132943 T3 DK4132943 T3 DK 4132943T3
Authority
DK
Denmark
Prior art keywords
immunoglobulin
binding proteins
affinity purification
affinity
purification
Prior art date
Application number
DK21736946.1T
Other languages
English (en)
Inventor
Paul Knick
Hanna Bobolowski
Mathias Kahl
Erik Fiedler
Ulrich Haupts
Original Assignee
Navigo Proteins Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Navigo Proteins Gmbh filed Critical Navigo Proteins Gmbh
Application granted granted Critical
Publication of DK4132943T3 publication Critical patent/DK4132943T3/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39516Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum from serum, plasma
    • A61K39/39525Purification
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • C07K1/22Affinity chromatography or related techniques based upon selective absorption processes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/42Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/42Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4283Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Immunology (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
DK21736946.1T 2020-07-15 2021-07-14 Immunoglobulin-bindende proteiner til affinitetsoprensning DK4132943T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP20186024 2020-07-15
EP21158714 2021-02-23
PCT/EP2021/069564 WO2022013272A1 (en) 2020-07-15 2021-07-14 Immunoglobulin binding proteins for affinity purification

Publications (1)

Publication Number Publication Date
DK4132943T3 true DK4132943T3 (da) 2024-07-22

Family

ID=76807674

Family Applications (1)

Application Number Title Priority Date Filing Date
DK21736946.1T DK4132943T3 (da) 2020-07-15 2021-07-14 Immunoglobulin-bindende proteiner til affinitetsoprensning

Country Status (10)

Country Link
US (1) US12570690B2 (da)
EP (2) EP4424706A3 (da)
JP (1) JP7606783B2 (da)
KR (1) KR20230038529A (da)
CN (1) CN115812075A (da)
AU (1) AU2021307552B2 (da)
CA (1) CA3184992A1 (da)
DK (1) DK4132943T3 (da)
LT (1) LT4132943T (da)
WO (1) WO2022013272A1 (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2023395034A1 (en) * 2022-12-16 2025-07-31 Navigo Proteins Gmbh New ligands for affinity chromatography
EP4541444A1 (en) 2023-10-20 2025-04-23 Cytiva BioProcess R&D AB Fusion protein for affinity capture
WO2025250805A1 (en) 2024-05-31 2025-12-04 Purolite Llc Protein a chromatography viral clearance at elution greater than ph 4

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7709209B2 (en) * 2002-03-25 2010-05-04 Ge Healthcare Bio-Sciences Ab Protein ligands
SG195555A1 (en) * 2008-12-24 2013-12-30 Emd Millipore Corp Caustic stable chromatography ligands
NL2004481C2 (nl) 2010-03-31 2011-10-04 Sagem Identification B V Werkwijze voor het vervaardigen van een driedimensionale afbeelding op basis van berekende beeldrotaties.
CN103403020A (zh) * 2010-12-21 2013-11-20 Jsr株式会社 蛋白a的新型耐碱变体及其在亲和色谱中的用途
DE102015212250A1 (de) 2015-06-30 2017-01-05 Conti Temic Microelectronic Gmbh Verbesserte Berechnung der Zeit bis zur Kollision für ein Fahrzeug
ES2916101T3 (es) * 2015-07-16 2022-06-28 Navigo Proteins Gmbh Nuevas proteínas de unión a inmunoglobulina y su uso en la purificación por afinidad
EP3497117B1 (en) * 2016-08-11 2024-01-24 Navigo Proteins GmbH Novel alkaline stable immunoglobulin-binding proteins
EP3521304B9 (en) * 2018-02-01 2023-10-04 Repligen Corporation Fc binding proteins with cysteine in the c-terminal helical region
CN111315887B (zh) * 2017-11-09 2024-02-06 东曹株式会社 免疫球蛋白结合性蛋白质
EP3650465A1 (en) * 2018-11-12 2020-05-13 Navigo Proteins Gmbh Novel populations of polypeptides having a triple-helical structure
EP4077357B1 (en) * 2019-12-17 2023-09-06 Navigo Proteins Gmbh Binding proteins for the enzyme acid alpha glucosidase (gaa) and uses thereof

Also Published As

Publication number Publication date
CN115812075A (zh) 2023-03-17
AU2021307552A9 (en) 2023-03-09
KR20230038529A (ko) 2023-03-20
WO2022013272A1 (en) 2022-01-20
LT4132943T (lt) 2024-07-25
JP7606783B2 (ja) 2024-12-26
AU2021307552B2 (en) 2025-12-04
US12570690B2 (en) 2026-03-10
US20230295223A1 (en) 2023-09-21
EP4132943B1 (en) 2024-05-29
JP2023533529A (ja) 2023-08-03
EP4424706A3 (en) 2025-01-08
AU2021307552A1 (en) 2023-02-09
CA3184992A1 (en) 2022-01-20
EP4424706A2 (en) 2024-09-04
EP4132943A1 (en) 2023-02-15

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