DK420588A - (aryl eller heteroaromatisk methyl)-2,2'-bi-1h-imidazoler, deres fremstilling og anvendelse - Google Patents

(aryl eller heteroaromatisk methyl)-2,2'-bi-1h-imidazoler, deres fremstilling og anvendelse

Info

Publication number
DK420588A
DK420588A DK420588A DK420588A DK420588A DK 420588 A DK420588 A DK 420588A DK 420588 A DK420588 A DK 420588A DK 420588 A DK420588 A DK 420588A DK 420588 A DK420588 A DK 420588A
Authority
DK
Denmark
Prior art keywords
aryl
imidazoles
preparation
heteroaromatic methyl
substituted
Prior art date
Application number
DK420588A
Other languages
English (en)
Other versions
DK420588D0 (da
Inventor
Donald P Matthews
James R Mccarthy
Jeffrey P Whitten
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of DK420588D0 publication Critical patent/DK420588D0/da
Publication of DK420588A publication Critical patent/DK420588A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Peptides Or Proteins (AREA)
DK420588A 1987-07-28 1988-07-27 (aryl eller heteroaromatisk methyl)-2,2'-bi-1h-imidazoler, deres fremstilling og anvendelse DK420588A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/078,352 US4839375A (en) 1987-07-28 1987-07-28 (Aryl or heteroaromatic methyl)-2,2'-bi-1H-imidazoles and their use as anti-hypertensive agents

Publications (2)

Publication Number Publication Date
DK420588D0 DK420588D0 (da) 1988-07-27
DK420588A true DK420588A (da) 1989-01-29

Family

ID=22143494

Family Applications (1)

Application Number Title Priority Date Filing Date
DK420588A DK420588A (da) 1987-07-28 1988-07-27 (aryl eller heteroaromatisk methyl)-2,2'-bi-1h-imidazoler, deres fremstilling og anvendelse

Country Status (19)

Country Link
US (1) US4839375A (da)
EP (1) EP0301456B1 (da)
JP (1) JP2750578B2 (da)
KR (1) KR970011301B1 (da)
CN (1) CN1016173B (da)
AT (1) ATE101151T1 (da)
AU (1) AU605609B2 (da)
CA (1) CA1338786C (da)
DE (1) DE3887585T2 (da)
DK (1) DK420588A (da)
ES (1) ES2063008T3 (da)
FI (1) FI883499A7 (da)
HU (1) HU202861B (da)
IL (1) IL87217A (da)
NO (1) NO169841C (da)
NZ (1) NZ225561A (da)
PH (1) PH26551A (da)
PT (1) PT88121B (da)
ZA (1) ZA885360B (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0949314B1 (en) * 1998-03-20 2006-06-14 China Petrochemical Corporation Hydrodesulfurisation of hydrocarbon oils

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1283661C (en) * 1984-06-20 1991-04-30 Franz Jansen Imidazolides, process for their preparation and application as intermediates for the synthesis of cytotoxic conjugates
CA1286301C (en) * 1985-11-25 1991-07-16 Donald P. Matthews 2,2'-bi-1h-imidazoles
IL82401A0 (en) * 1986-05-06 1987-11-30 Merrell Dow Pharma Dopamine beta hydroxy-lase inhibiting imidazole derivatives and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
IL87217A0 (en) 1988-12-30
PT88121B (pt) 1995-03-01
JP2750578B2 (ja) 1998-05-13
CA1338786C (en) 1996-12-10
DK420588D0 (da) 1988-07-27
DE3887585T2 (de) 1994-05-26
FI883499A0 (fi) 1988-07-25
US4839375A (en) 1989-06-13
EP0301456B1 (en) 1994-02-02
NZ225561A (en) 1990-12-21
EP0301456A2 (en) 1989-02-01
FI883499L (fi) 1989-01-29
KR890002112A (ko) 1989-04-08
PT88121A (pt) 1989-07-31
KR970011301B1 (ko) 1997-07-09
ATE101151T1 (de) 1994-02-15
JPS6440465A (en) 1989-02-10
AU1976588A (en) 1989-02-02
ZA885360B (en) 1989-03-29
NO169841B (no) 1992-05-04
HUT53900A (en) 1990-12-28
CN1034718A (zh) 1989-08-16
AU605609B2 (en) 1991-01-17
CN1016173B (zh) 1992-04-08
ES2063008T3 (es) 1995-01-01
EP0301456A3 (en) 1990-12-05
HU202861B (en) 1991-04-29
DE3887585D1 (de) 1994-03-17
NO169841C (no) 1992-08-12
IL87217A (en) 1992-07-15
FI883499A7 (fi) 1989-01-29
NO883322D0 (no) 1988-07-27
PH26551A (en) 1992-08-19
NO883322L (no) 1989-01-30

Similar Documents

Publication Publication Date Title
DK89595A (da) Fremgangsmåde til fremstilling af 1-(3-dimethylaminopropyl)-1'-(4-fluorphenyl)-1,3-dihydroisobenzofuran-5-carbonnitril
NO178969C (no) Analogifremgangsmåte for fremstilling av terapeutisk aktive, substituerte kinazolinoner
NO902301D0 (no) Fremgangsmaate for fremstilling av diarylstyrylkinolin-disyrer.
MX17846A (es) Proceso para la preparacion de nuevos derivados de 9h purina.
FI101376B1 (fi) Menetelmä 3-bentsyyliamino-2-fenyylipiperidiinijohdannaisten valmistamiseksi
ES8503346A1 (es) "un procedimiento para preparar un derivado de -(4-(2-piridil)-pi-peracino)-alcanoilanilida".
BG44204A3 (en) Method for preparing of 2- oxyindol derivatives
ES545194A0 (es) Un procedimiento para preparar derivados de purina
IT8420358A0 (it) Procedimento di preparazione di derivati 1-carbamoilmetilici di 4-idrossi-2-osso-pirrolidina nonche' di intermedi per ottenere tali composti.
FI873790A0 (fi) Kinoxalinfoereningar och deras framstaellning och anvaendning.
FR2567514B1 (fr) Nouveaux ether-oxydes derives de cyclopropylphenols
DK420588D0 (da) (aryl eller heteroaromatisk methyl)-2,2'-bi-1h-imidazoler, deres fremstilling og anvendelse
NO904135D0 (no) Fremgangsmaate for fremstilling av nye alkylpiperidiner.
ES2046528T3 (es) Derivados heterotetraciclicos de lactamas, proceso para su preparacion y composiciones farmaceuticas a base de los mismos.
DK23887D0 (da) Benzimidazolderivater
ES552874A0 (es) Un procedimiento para preparar benzo (c)-1,5-naftiridinas
DK0521766T3 (da) Hidtil ukendt fremgangsmåde til syntese af enantiomerer af 3-aminochromanderivater
ES535794A0 (es) Un procedimiento para preparar nuevas 5-aminometil-imidazol-1-il-1,3-dialquil-1h-pirazol-4-il-aroil-metanonas
DK437787A (da) 2,6-bis-(chlormethyloxy-carbonyloxymethyl)-pyridinsamt fremgangsmaade til fremstilling deraf
KR830005134A (ko) 항부정맥 작용 및 혈소판 응집 억제 작용을 갖는 심근 보호용 피롤 유도체의 제조방법
FI892731L (fi) Foerfarande foer framstaellning av nya antiallergiska medel.
IT7827750A0 (it) Processo per la preparazione di derivati 1,4-diidro-piridinici.
FI870098A0 (fi) Nya pregnanderivat, foerfaranden foer deras framstaellning och farmaceutiska preparat, vilka innehaoller desamma.
ES8606375A1 (es) Un procedimiento para preparar un derivado de aminoprpilaminobleomicina

Legal Events

Date Code Title Description
ATS Application withdrawn