DK4279919T3 - Fremgangsmåde til screening for neuronal regenerationsfremmende celler med neuronal regenerationsaktivitet - Google Patents

Fremgangsmåde til screening for neuronal regenerationsfremmende celler med neuronal regenerationsaktivitet

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Publication number
DK4279919T3
DK4279919T3 DK22739669.4T DK22739669T DK4279919T3 DK 4279919 T3 DK4279919 T3 DK 4279919T3 DK 22739669 T DK22739669 T DK 22739669T DK 4279919 T3 DK4279919 T3 DK 4279919T3
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DK
Denmark
Prior art keywords
neuronal regeneration
screening
activity
promoting cells
neuronal
Prior art date
Application number
DK22739669.4T
Other languages
English (en)
Inventor
Jaeseung Lim
Min Young Kim
Min Ki Sung
Original Assignee
Cellatoz Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from KR1020220004077A external-priority patent/KR102668084B1/ko
Application filed by Cellatoz Therapeutics Inc filed Critical Cellatoz Therapeutics Inc
Application granted granted Critical
Publication of DK4279919T3 publication Critical patent/DK4279919T3/da

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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0619—Neurons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0668—Mesenchymal stem cells from other natural sources
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5073—Stem cells
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/13—Nerve growth factor [NGF]; Brain-derived neurotrophic factor [BDNF]; Cilliary neurotrophic factor [CNTF]; Glial-derived neurotrophic factor [GDNF]; Neurotrophins [NT]; Neuregulins
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/135—Platelet-derived growth factor [PDGF]
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/40—Regulators of development
    • C12N2501/41—Hedgehog proteins; Cyclopamine (inhibitor)
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/50—Cell markers; Cell surface determinants
    • C12N2501/599—Cell markers; Cell surface determinants with CD designations not provided for elsewhere
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/13—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells
    • C12N2506/1346—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells
    • C12N2506/1384—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells from adipose-derived stem cells [ADSC], from adipose stromal stem cells
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/13—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells
    • C12N2506/1346—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells
    • C12N2506/1392—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells from mesenchymal stem cells from other natural sources
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    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins
    • C12N2533/52—Fibronectin; Laminin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans

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  • Health & Medical Sciences (AREA)
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  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Neurology (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Developmental Biology & Embryology (AREA)
  • Neurosurgery (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
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  • Urology & Nephrology (AREA)
  • Dispersion Chemistry (AREA)
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  • Food Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
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DK22739669.4T 2021-01-12 2022-01-12 Fremgangsmåde til screening for neuronal regenerationsfremmende celler med neuronal regenerationsaktivitet DK4279919T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR20210003879 2021-01-12
KR1020220004077A KR102668084B1 (ko) 2021-01-12 2022-01-11 신경 재생 활성을 가진 신경재생촉진세포의 스크리닝 방법
PCT/KR2022/000553 WO2022154474A1 (ko) 2021-01-12 2022-01-12 신경 재생 활성을 가진 신경재생촉진세포의 스크리닝 방법

Publications (1)

Publication Number Publication Date
DK4279919T3 true DK4279919T3 (da) 2026-05-26

Family

ID=82447402

Family Applications (1)

Application Number Title Priority Date Filing Date
DK22739669.4T DK4279919T3 (da) 2021-01-12 2022-01-12 Fremgangsmåde til screening for neuronal regenerationsfremmende celler med neuronal regenerationsaktivitet

Country Status (8)

Country Link
US (1) US20230392114A1 (da)
EP (1) EP4279919B1 (da)
JP (1) JP7785378B2 (da)
AU (1) AU2022207858B2 (da)
CA (1) CA3200810A1 (da)
DK (1) DK4279919T3 (da)
FI (1) FI4279919T3 (da)
WO (1) WO2022154474A1 (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20240358764A1 (en) * 2023-04-28 2024-10-31 Cellatoz Therapeutics, Inc. NEURONAL REGENERATION PROMOTING CELLS (NRPCs) AND TREATING DAMAGED NERVE CELLS
KR20250087216A (ko) * 2023-12-07 2025-06-16 연세대학교 원주산학협력단 편도 유래 중간엽 줄기세포 제조방법

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2569780T3 (es) * 2003-06-27 2016-05-12 DePuy Synthes Products, Inc. Células posparto derivadas de tejido placentario y métodos de preparación y uso de las mismas
JP4147305B2 (ja) * 2004-01-23 2008-09-10 国立大学法人 熊本大学 ヒト成体由来の膵臓内分泌細胞に分化可能な細胞に特有な表面抗原とこの表面抗原による細胞分離法
US7947435B2 (en) 2007-01-19 2011-05-24 Seoul National University Industry Foundation Neuronal regeneration material screening method by ex vivo model
WO2008150001A1 (ja) 2007-06-08 2008-12-11 Biomaster, Inc. アディポクラスタ－
ES2729557T3 (es) 2008-05-28 2019-11-04 Univ Ramot Células madre mesenquimatosas para el tratamiento de enfermedades del SNC
WO2013151725A1 (en) * 2012-04-05 2013-10-10 The Regents Of The University Of California Regenerative sera cells and mesenchymal stem cells
GB201513996D0 (en) * 2015-08-07 2015-09-23 Cell Therapy Ltd Immuno-oncology mesodermal progenitor (IOMP) cell
US20170258843A1 (en) * 2016-03-14 2017-09-14 AngioStem, Inc. Stem cell mediated neuroregeneration and neuroprotection
WO2017188457A1 (ja) 2016-04-28 2017-11-02 北海道公立大学法人札幌医科大学 シナプス形成剤

Also Published As

Publication number Publication date
AU2022207858B2 (en) 2025-11-13
JP7785378B2 (ja) 2025-12-15
WO2022154474A1 (ko) 2022-07-21
US20230392114A1 (en) 2023-12-07
AU2022207858A1 (en) 2023-06-22
CA3200810A1 (en) 2022-07-21
JP2024502646A (ja) 2024-01-22
EP4279919A4 (en) 2025-01-08
FI4279919T3 (fi) 2026-06-04
EP4279919A1 (en) 2023-11-22
EP4279919B1 (en) 2026-04-29