DK43489A - Immunotoksin og fremgangsmaade til dets fremstilling - Google Patents

Immunotoksin og fremgangsmaade til dets fremstilling

Info

Publication number
DK43489A
DK43489A DK043489A DK43489A DK43489A DK 43489 A DK43489 A DK 43489A DK 043489 A DK043489 A DK 043489A DK 43489 A DK43489 A DK 43489A DK 43489 A DK43489 A DK 43489A
Authority
DK
Denmark
Prior art keywords
immunotoxin
procedure
preparation
Prior art date
Application number
DK043489A
Other languages
English (en)
Other versions
DK43489D0 (da
Inventor
Raymond Francis Ebert
Original Assignee
Akzo Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nv filed Critical Akzo Nv
Publication of DK43489D0 publication Critical patent/DK43489D0/da
Publication of DK43489A publication Critical patent/DK43489A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07G—COMPOUNDS OF UNKNOWN CONSTITUTION
    • C07G99/00—Subject matter not provided for in other groups of this subclass
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
    • A61K47/6811—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
    • A61K47/6817—Toxins
    • A61K47/6819—Plant toxins
    • A61K47/6825—Ribosomal inhibitory proteins, i.e. RIP-I or RIP-II, e.g. Pap, gelonin or dianthin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Botany (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK043489A 1988-02-02 1989-01-31 Immunotoksin og fremgangsmaade til dets fremstilling DK43489A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US15149988A 1988-02-02 1988-02-02

Publications (2)

Publication Number Publication Date
DK43489D0 DK43489D0 (da) 1989-01-31
DK43489A true DK43489A (da) 1989-08-03

Family

ID=22539046

Family Applications (1)

Application Number Title Priority Date Filing Date
DK043489A DK43489A (da) 1988-02-02 1989-01-31 Immunotoksin og fremgangsmaade til dets fremstilling

Country Status (9)

Country Link
EP (1) EP0327169A3 (da)
JP (1) JPH02152991A (da)
KR (1) KR890013045A (da)
AU (1) AU2883889A (da)
DK (1) DK43489A (da)
FI (1) FI890467A7 (da)
IE (1) IE890206L (da)
PT (1) PT89584A (da)
ZA (1) ZA89547B (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6329508B1 (en) 1989-09-07 2001-12-11 Alkermes, Inc. Transferrin receptor reactive chimeric antibodies
US5977307A (en) * 1989-09-07 1999-11-02 Alkermes, Inc. Transferrin receptor specific ligand-neuropharmaceutical agent fusion proteins
US5182107A (en) * 1989-09-07 1993-01-26 Alkermes, Inc. Transferrin receptor specific antibody-neuropharmaceutical or diagnostic agent conjugates
US5527527A (en) * 1989-09-07 1996-06-18 Alkermes, Inc. Transferrin receptor specific antibody-neuropharmaceutical agent conjugates
US5154924A (en) * 1989-09-07 1992-10-13 Alkermes, Inc. Transferrin receptor specific antibody-neuropharmaceutical agent conjugates
US5672683A (en) * 1989-09-07 1997-09-30 Alkermes, Inc. Transferrin neuropharmaceutical agent fusion protein
DE4014540A1 (de) * 1990-05-07 1991-11-14 Klaus Dr Tschaikowsky Immunkonjugate zur prophylaxe und therapie von organschaeden bei entzuendlichen prozessen
DE4040954C2 (de) * 1990-12-20 2001-05-17 Max Planck Gesellschaft Verfahren zur Erzeugung von pathogen-resistenten Pflanzen
US6015555A (en) * 1995-05-19 2000-01-18 Alkermes, Inc. Transferrin receptor specific antibody-neuropharmaceutical or diagnostic agent conjugates

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4664911A (en) * 1983-06-21 1987-05-12 Board Of Regents, University Of Texas System Immunotoxin conjugates employing toxin B chain moieties
ATE87318T1 (de) * 1985-11-29 1993-04-15 Consolidated Pharmaceuticals L Ricin-antikoerper-konjugate.

Also Published As

Publication number Publication date
FI890467A0 (fi) 1989-02-01
DK43489D0 (da) 1989-01-31
ZA89547B (en) 1989-10-25
KR890013045A (ko) 1989-09-21
EP0327169A3 (en) 1990-07-11
EP0327169A2 (en) 1989-08-09
JPH02152991A (ja) 1990-06-12
FI890467L (fi) 1989-08-03
FI890467A7 (fi) 1989-08-03
IE890206L (en) 1989-08-02
AU2883889A (en) 1989-08-03
PT89584A (pt) 1989-10-04

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment