DK441588A - Pulmonaere hydofobe proteiner, associeret med overfladeaktivitet - Google Patents

Pulmonaere hydofobe proteiner, associeret med overfladeaktivitet

Info

Publication number
DK441588A
DK441588A DK441588A DK441588A DK441588A DK 441588 A DK441588 A DK 441588A DK 441588 A DK441588 A DK 441588A DK 441588 A DK441588 A DK 441588A DK 441588 A DK441588 A DK 441588A
Authority
DK
Denmark
Prior art keywords
hydofobe
pulmonary
proteins
surface activity
activity
Prior art date
Application number
DK441588A
Other languages
Danish (da)
English (en)
Other versions
DK441588D0 (da
Inventor
Jeffrey A Whitsett
J Lawrence Fox
Tami J Pilot-Matias
Joseph L Meuth
Virende K Sarin
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of DK441588D0 publication Critical patent/DK441588D0/da
Publication of DK441588A publication Critical patent/DK441588A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C12N15/72—Expression systems using regulatory sequences derived from the lac-operon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/42—Respiratory system, e.g. lungs, bronchi or lung cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/785—Alveolar surfactant peptides; Pulmonary surfactant peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/035—Fusion polypeptide containing a localisation/targetting motif containing a signal for targeting to the external surface of a cell, e.g. to the outer membrane of Gram negative bacteria, GPI- anchored eukaryote proteins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Plant Pathology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Physiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK441588A 1986-12-08 1988-08-05 Pulmonaere hydofobe proteiner, associeret med overfladeaktivitet DK441588A (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US93920686A 1986-12-08 1986-12-08
US6071987A 1987-06-10 1987-06-10
US10168087A 1987-10-01 1987-10-01
PCT/US1987/003180 WO1988004324A1 (fr) 1986-12-08 1987-12-03 Proteines associees a des tensioactifs hydrophobes pulmonaires

Publications (2)

Publication Number Publication Date
DK441588D0 DK441588D0 (da) 1988-08-05
DK441588A true DK441588A (da) 1988-08-05

Family

ID=27369890

Family Applications (1)

Application Number Title Priority Date Filing Date
DK441588A DK441588A (da) 1986-12-08 1988-08-05 Pulmonaere hydofobe proteiner, associeret med overfladeaktivitet

Country Status (7)

Country Link
EP (1) EP0307513A3 (fr)
JP (1) JPH01501282A (fr)
KR (1) KR890700167A (fr)
AU (1) AU616164B2 (fr)
DK (1) DK441588A (fr)
OA (1) OA08748A (fr)
WO (1) WO1988004324A1 (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4933280A (en) * 1984-12-11 1990-06-12 California Biotechnology Inc. Recombinant DNA sequence encoding Alveolar Surfactant Protein
AU1996388A (en) * 1987-07-01 1989-01-30 Kabigen Ab Proteins and protein compositions and their use
AU619226B2 (en) * 1987-09-28 1992-01-23 Children's Hospital Medical Center Human cell lines of epithelial lung adenocarcinoma origin, human proteins and methods
SE8803713D0 (sv) * 1988-10-18 1988-10-18 Kabigen Ab Biologically active lipoprotein and its use
US5238920A (en) * 1989-08-22 1993-08-24 Abbott Laboratories Pulmonary surfactant protein fragments
US5258496A (en) * 1990-07-10 1993-11-02 Scios Nova Inc. Isolation and purification of lung surfactant protein
US5272252A (en) * 1991-11-04 1993-12-21 Merrell Dow Pharmaceuticals Inc. Synthetic lung surfactant having antioxidant properties
DE69332654T2 (de) * 1992-04-10 2003-09-25 Abbott Laboratories, Abbott Park Fragmente eines oberflächenaktiven lungenproteins
JPH05294996A (ja) * 1992-04-17 1993-11-09 Tokyo Tanabe Co Ltd 合成ペプチド、それを含有する肺サーファクタント及び呼吸窮迫症候群治療剤
AU667438B2 (en) * 1993-04-30 1996-03-21 Mitsubishi-Tokyo Pharmaceuticals, Inc. Method of purifying hydrophobic polypeptide
PT733645E (pt) * 1993-12-08 2003-07-31 Mitsubishi Pharma Corp Novo peptido sintetico tensoactivo pulmonar que o contem e medicamento para sindroma da insuficiencia respiratoria
RU2144925C1 (ru) * 1993-12-08 2000-01-27 ТТ Фармасьютикалс, Инк. Новые синтетические пептиды, легочная поверхностно-активная композиция, лекарственный препарат для лечения респираторного дистресс-синдрома
US6020307A (en) * 1997-04-25 2000-02-01 Ony, Inc. Compositions and methods for isolating lung surfactant hydrophobic proteins SP-B and SP-C
AU2815297A (en) * 1996-04-26 1997-11-19 Ony, Inc. Compositions and methods for isolating lung surfactant hydrophobic proteins sp-b and sp-c
JP2003501481A (ja) * 1999-06-11 2003-01-14 ビイク グルデン ロンベルク ヒエーミツシエ フアブリーク ゲゼルシヤフト ミツト ベシユレンクテル ハフツング サーファクタントタンパク質ｂ（ｓｐ−ｂ）改変体およびサーファクタントタンパク質ｃ（ｓｐ−ｃ）改変体を含有する医薬品製剤

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4016258A (en) * 1975-08-05 1977-04-05 Said Sami I Vasoactive intestinal peptide from fowl
SE7804098L (sv) * 1977-04-20 1978-10-21 R & Z Vermoegensverw Gmbh Peptidkomplex fran dna-haltiga organismer
JPS55160721A (en) * 1979-06-02 1980-12-13 Tokyo Tanabe Co Ltd Pulmonary surfactant ta-546, its preparation, and remedy for pulmonary hyaline membrane syndrome comprising it as active constituent
US4659805A (en) * 1984-12-11 1987-04-21 California Biotechnology, Inc. Recombinant alveolar surfactant protein
US4933280A (en) * 1984-12-11 1990-06-12 California Biotechnology Inc. Recombinant DNA sequence encoding Alveolar Surfactant Protein
WO1987002037A1 (fr) * 1985-09-26 1987-04-09 Genetics Institute, Inc. Proteines tensio-actives pulmonaires

Also Published As

Publication number Publication date
AU1052388A (en) 1988-06-30
EP0307513A3 (fr) 1990-01-10
AU616164B2 (en) 1991-10-24
DK441588D0 (da) 1988-08-05
OA08748A (en) 1989-03-31
KR890700167A (ko) 1989-03-10
EP0307513A2 (fr) 1989-03-22
JPH01501282A (ja) 1989-05-11
WO1988004324A1 (fr) 1988-06-16

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment