DK443881A - Fremgangsmaade til fremstilling af 5-substituerede 9-cyanmethylendithieno (3,4-b.4!.3!-e) azepiner - Google Patents

Fremgangsmaade til fremstilling af 5-substituerede 9-cyanmethylendithieno (3,4-b.4!.3!-e) azepiner

Info

Publication number: DK443881A
Authority: DK; Denmark
Prior art keywords: carbon atoms; substituted; nitrogen; oxygen; membered
Prior art date: 1980-10-08

Application number

DK443881A

Other languages

English (en)

Other versions

DK152289B (da

DK152289C (da

Inventor

G Steiner

H J Teschendorf

H Kreiskott

H P Hofmann

Original Assignee

Basf Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1980-10-08

Filing date

1981-10-07

Publication date

1982-04-09

1981-10-07 Application filed by Basf Ag filed Critical Basf Ag

1982-04-09 Publication of DK443881A publication Critical patent/DK443881A/da

1988-02-15 Publication of DK152289B publication Critical patent/DK152289B/da

1988-07-11 Application granted granted Critical

1988-07-11 Publication of DK152289C publication Critical patent/DK152289C/da

Links

150000001538 azepines Chemical class 0.000 title 1
IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 20
125000004432 carbon atom Chemical group C* 0.000 abstract 18
229910052757 nitrogen Inorganic materials 0.000 abstract 12
125000000217 alkyl group Chemical group 0.000 abstract 8
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 6
229910052760 oxygen Inorganic materials 0.000 abstract 6
239000001301 oxygen Substances 0.000 abstract 6
239000002253 acid Substances 0.000 abstract 4
125000000753 cycloalkyl group Chemical group 0.000 abstract 4
125000005842 heteroatom Chemical group 0.000 abstract 4
125000002768 hydroxyalkyl group Chemical group 0.000 abstract 4
229920006395 saturated elastomer Polymers 0.000 abstract 4
150000001204 N-oxides Chemical class 0.000 abstract 3
150000003839 salts Chemical class 0.000 abstract 3
WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 2
ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 2
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
125000004183 alkoxy alkyl group Chemical group 0.000 abstract 2
125000003545 alkoxy group Chemical group 0.000 abstract 2
125000000304 alkynyl group Chemical group 0.000 abstract 2
150000001412 amines Chemical class 0.000 abstract 2
125000004103 aminoalkyl group Chemical group 0.000 abstract 2
GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 2
229910052794 bromium Inorganic materials 0.000 abstract 2
229910052801 chlorine Inorganic materials 0.000 abstract 2
239000000460 chlorine Substances 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
239000000470 constituent Substances 0.000 abstract 2
125000004981 cycloalkylmethyl group Chemical group 0.000 abstract 2
229910052736 halogen Inorganic materials 0.000 abstract 2
150000002367 halogens Chemical class 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
125000004433 nitrogen atom Chemical group N* 0.000 abstract 2
-1 5-substituted 9-cyanomethylene-dithieno-[3,4-b:4',3'-e]azepine Chemical class 0.000 abstract 1
XYOVOXDWRFGKEX-UHFFFAOYSA-N azepine Chemical compound N1C=CC=CC=C1 XYOVOXDWRFGKEX-UHFFFAOYSA-N 0.000 abstract 1
239000012038 nucleophile Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/14—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Neurosurgery (AREA)
Life Sciences & Earth Sciences (AREA)
Neurology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Biomedical Technology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Anesthesiology (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Plural Heterocyclic Compounds (AREA)
Other In-Based Heterocyclic Compounds (AREA)

DK443881A 1980-10-08 1981-10-07 Analogifremgangsmaade til fremstilling af 5-substituerede 9-cyanmethylen-dithieno(3,4-b:4`,3`-e)azepiner eller syreadditionssalte deraf DK152289C (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE19803037971 DE3037971A1 (de)	1980-10-08	1980-10-08	5-substituierte 9-cyanmethylendithieno (3,4-b:4' 3'-e) -azepine
DE3037971		1980-10-08

Publications (3)

Publication Number	Publication Date
DK443881A true DK443881A (da)	1982-04-09
DK152289B DK152289B (da)	1988-02-15
DK152289C DK152289C (da)	1988-07-11

Family

ID=6113891

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK443881A DK152289C (da)	1980-10-08	1981-10-07	Analogifremgangsmaade til fremstilling af 5-substituerede 9-cyanmethylen-dithieno(3,4-b:4`,3`-e)azepiner eller syreadditionssalte deraf

Country Status (8)

Country	Link
EP (1)	EP0050212B1 (da)
JP (1)	JPS5788179A (da)
AT (1)	ATE5820T1 (da)
CA (1)	CA1170258A (da)
DE (2)	DE3037971A1 (da)
DK (1)	DK152289C (da)
IE (1)	IE51635B1 (da)
ZA (1)	ZA816927B (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3309719A1 (de) *	1983-03-18	1984-09-20	Basf Ag, 6700 Ludwigshafen	2,3,5,6-tetrasubstituierte p-benzochinone, ihre herstellung und verwendung
DE3524743A1 (de) *	1985-07-11	1987-01-15	Basf Ag	Verfahren zur herstellung von 4,5-dihydro-dithieno-(3,4-b:4',3'-e)-azepin-5,9-dion
DE3524744A1 (de) *	1985-07-11	1987-01-15	Basf Ag	4-substituierte 10-cyanmethylen-thieno (4,3-e)-benzo-azepine
DE3717068A1 (de) *	1987-05-21	1988-12-08	Basf Ag	4-substituierte 10-cyanmethylen-pyrrolo(4,3-e)-benzo-azepine
DE3717069A1 (de) *	1987-05-21	1988-12-08	Basf Ag	5-substituierte 10-cyanmethylen-thieno(3,4-b)-benzo-azepine
CA2740029C (en) *	2008-05-16	2016-12-20	Axis, Inc.	Pharmaceutical composition for treatment of fibromyalgia

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH560220A5 (en) *	1971-11-26	1975-03-27	Wander Ag Dr A	4-(1-piperazinyl)-10h-thieno (3,2-c) (1) benzaepines - - antipsychotics, sedatives, hypnotics or muscle relaxants
DE2918778A1 (de) *	1979-05-10	1980-11-20	Basf Ag	6-substituierte 11-alkylen-morphantridine

1980
- 1980-10-08 DE DE19803037971 patent/DE3037971A1/de not_active Withdrawn
1981
- 1981-09-17 DE DE8181107343T patent/DE3161895D1/de not_active Expired
- 1981-09-17 EP EP81107343A patent/EP0050212B1/de not_active Expired
- 1981-09-17 AT AT81107343T patent/ATE5820T1/de not_active IP Right Cessation
- 1981-10-01 JP JP56154922A patent/JPS5788179A/ja active Granted
- 1981-10-06 IE IE2330/81A patent/IE51635B1/en unknown
- 1981-10-07 DK DK443881A patent/DK152289C/da active
- 1981-10-07 CA CA000387495A patent/CA1170258A/en not_active Expired
- 1981-10-07 ZA ZA816927A patent/ZA816927B/xx unknown

Also Published As

Publication number	Publication date
DE3161895D1 (en)	1984-02-16
EP0050212B1 (de)	1984-01-11
JPH0243754B2 (da)	1990-10-01
CA1170258A (en)	1984-07-03
JPS5788179A (en)	1982-06-01
DK152289B (da)	1988-02-15
IE51635B1 (en)	1987-01-21
DE3037971A1 (de)	1982-05-13
IE812330L (en)	1982-04-08
DK152289C (da)	1988-07-11
ATE5820T1 (de)	1984-01-15
ZA816927B (en)	1982-10-27
EP0050212A1 (de)	1982-04-28

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