DK448983A - 1-monophosphatestere, 1,3-bisphosphatestere og cykliske phosphatestere af 9-(1,3-dihydroxy-2-propoxymethyl)guanin som antivirale midler - Google Patents

1-monophosphatestere, 1,3-bisphosphatestere og cykliske phosphatestere af 9-(1,3-dihydroxy-2-propoxymethyl)guanin som antivirale midler Download PDF

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Publication number
DK448983A
DK448983A DK448983A DK448983A DK448983A DK 448983 A DK448983 A DK 448983A DK 448983 A DK448983 A DK 448983A DK 448983 A DK448983 A DK 448983A DK 448983 A DK448983 A DK 448983A
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DK
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Prior art keywords
testers
propoxymethyl
bisphosphate
monophosphate
guanine
Prior art date
Application number
DK448983A
Other languages
Danish (da)
English (en)
Other versions
DK448983D0 (da
Inventor
Julien P H Verheyden
John C Martin
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of DK448983D0 publication Critical patent/DK448983D0/da
Publication of DK448983A publication Critical patent/DK448983A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/14—Unsaturated ethers
    • C07C43/17—Unsaturated ethers containing halogen
    • C07C43/174—Unsaturated ethers containing halogen containing six-membered aromatic rings
    • C07C43/1745—Unsaturated ethers containing halogen containing six-membered aromatic rings having more than one ether bound
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/14—Unsaturated ethers
    • C07C43/178—Unsaturated ethers containing hydroxy or O-metal groups
    • C07C43/1785—Unsaturated ethers containing hydroxy or O-metal groups having more than one ether bound
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK448983A 1982-09-30 1983-09-29 1-monophosphatestere, 1,3-bisphosphatestere og cykliske phosphatestere af 9-(1,3-dihydroxy-2-propoxymethyl)guanin som antivirale midler DK448983A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US43193382A 1982-09-30 1982-09-30
US46427483A 1983-02-07 1983-02-07

Publications (2)

Publication Number Publication Date
DK448983D0 DK448983D0 (da) 1983-09-29
DK448983A true DK448983A (da) 1984-03-31

Family

ID=27029273

Family Applications (1)

Application Number Title Priority Date Filing Date
DK448983A DK448983A (da) 1982-09-30 1983-09-29 1-monophosphatestere, 1,3-bisphosphatestere og cykliske phosphatestere af 9-(1,3-dihydroxy-2-propoxymethyl)guanin som antivirale midler

Country Status (7)

Country Link
EP (1) EP0105486A3 (fr)
AU (1) AU565012B2 (fr)
DK (1) DK448983A (fr)
ES (4) ES526064A0 (fr)
FI (1) FI833504L (fr)
NO (1) NO833526L (fr)
NZ (1) NZ205802A (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4880820A (en) * 1983-06-24 1989-11-14 Merck & Co., Inc. Guanine derivatives
EP0138683A3 (fr) * 1983-09-30 1988-01-20 Merck & Co. Inc. Dérivés de purine, leur application dans des compositions anti-virales
US4579849A (en) * 1984-04-06 1986-04-01 Merck & Co., Inc. N-alkylguanine acyclonucleosides as antiviral agents
CS264222B1 (en) * 1986-07-18 1989-06-13 Holy Antonin N-phosphonylmethoxyalkylderivatives of bases of pytimidine and purine and method of use them
CA1330794C (fr) * 1987-03-27 1994-07-19 Phillip Frost Composes antiviraux, formes et methodes pharmaceutiques
CN108794477A (zh) * 2018-08-06 2018-11-13 华东师范大学 一种n2取代鸟嘌呤类化合物的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4199574A (en) * 1974-09-02 1980-04-22 Burroughs Wellcome Co. Methods and compositions for treating viral infections and guanine acyclic nucleosides
US4347360A (en) * 1980-09-16 1982-08-31 Ens Bio Logicals Inc. Ring open nucleoside analogues
NZ201662A (en) * 1981-08-26 1986-07-11 Merck & Co Inc 9-(1,3-(and 2,3)-dihydroxy-1-(and 2)-propoxy-methyl)guanine derivatives and methods for their preparation

Also Published As

Publication number Publication date
ES542299A0 (es) 1986-04-01
ES542297A0 (es) 1986-04-01
ES8507550A1 (es) 1985-09-16
AU1972383A (en) 1984-04-05
ES8605533A1 (es) 1986-04-01
AU565012B2 (en) 1987-09-03
FI833504A7 (fi) 1984-03-31
ES8605520A1 (es) 1986-04-01
FI833504A0 (fi) 1983-09-29
ES8606870A1 (es) 1986-05-16
ES542298A0 (es) 1986-05-16
EP0105486A3 (fr) 1984-05-16
EP0105486A2 (fr) 1984-04-18
FI833504L (fi) 1984-03-31
NZ205802A (en) 1986-10-08
ES526064A0 (es) 1985-09-16
DK448983D0 (da) 1983-09-29
NO833526L (no) 1984-04-02

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AHB Application shelved due to non-payment