DK449988A - Farmaceutisk praeparat med dobbeltstrenget rna - Google Patents

Farmaceutisk praeparat med dobbeltstrenget rna

Info

Publication number
DK449988A
DK449988A DK449988A DK449988A DK449988A DK 449988 A DK449988 A DK 449988A DK 449988 A DK449988 A DK 449988A DK 449988 A DK449988 A DK 449988A DK 449988 A DK449988 A DK 449988A
Authority
DK
Denmark
Prior art keywords
double
pharmaceutical preparation
stranded rna
ternary complexes
surfactant
Prior art date
Application number
DK449988A
Other languages
English (en)
Other versions
DK449988D0 (da
Inventor
William A Carter
Original Assignee
Hem Res Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hem Res Inc filed Critical Hem Res Inc
Publication of DK449988D0 publication Critical patent/DK449988D0/da
Publication of DK449988A publication Critical patent/DK449988A/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/713—Double-stranded nucleic acids or oligonucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Dispersion Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Credit Cards Or The Like (AREA)
  • Holo Graphy (AREA)
  • Details Or Accessories Of Spraying Plant Or Apparatus (AREA)
DK449988A 1987-08-12 1988-08-11 Farmaceutisk praeparat med dobbeltstrenget rna DK449988A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8422687A 1987-08-12 1987-08-12

Publications (2)

Publication Number Publication Date
DK449988D0 DK449988D0 (da) 1988-08-11
DK449988A true DK449988A (da) 1989-02-13

Family

ID=22183613

Family Applications (1)

Application Number Title Priority Date Filing Date
DK449988A DK449988A (da) 1987-08-12 1988-08-11 Farmaceutisk praeparat med dobbeltstrenget rna

Country Status (20)

Country Link
EP (1) EP0303516B1 (da)
JP (1) JP2714021B2 (da)
KR (1) KR970007904B1 (da)
CN (1) CN1031325A (da)
AT (1) ATE108066T1 (da)
AU (3) AU2053688A (da)
CA (1) CA1327001C (da)
DE (1) DE3850535T2 (da)
DK (1) DK449988A (da)
FI (1) FI883734L (da)
HU (1) HU209749B (da)
IE (1) IE66830B1 (da)
IL (1) IL87415A (da)
MX (1) MX12643A (da)
NO (1) NO883564L (da)
NZ (1) NZ225755A (da)
PH (1) PH31174A (da)
PT (1) PT88248B (da)
RU (1) RU2061470C1 (da)
ZA (1) ZA885874B (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4963532A (en) * 1987-11-25 1990-10-16 Hem Research, Inc. dsRNA-based prevention of viral escape
EP0473576A4 (en) * 1989-05-19 1993-03-10 Hem Research, Inc. Short therapeutic dsrna of defined structure
AU6714094A (en) * 1993-04-28 1994-11-21 Ribozyme Pharmaceuticals, Inc. Ocular delivery of nucleic acid
JP2690276B2 (ja) * 1995-01-10 1997-12-10 科学技術振興事業団 静電結合型高分子ミセル薬物担体とその薬剤
US6506559B1 (en) 1997-12-23 2003-01-14 Carnegie Institute Of Washington Genetic inhibition by double-stranded RNA
AUPP249298A0 (en) 1998-03-20 1998-04-23 Ag-Gene Australia Limited Synthetic genes and genetic constructs comprising same I
CN101818145A (zh) 1998-03-20 2010-09-01 联邦科学和工业研究组织 控制基因表达
AU776150B2 (en) 1999-01-28 2004-08-26 Medical College Of Georgia Research Institute, Inc. Composition and method for (in vivo) and (in vitro) attenuation of gene expression using double stranded RNA
US6423885B1 (en) 1999-08-13 2002-07-23 Commonwealth Scientific And Industrial Research Organization (Csiro) Methods for obtaining modified phenotypes in plant cells
KR20080023768A (ko) 2000-03-30 2008-03-14 화이트헤드 인스티튜트 포 바이오메디칼 리서치 Ｒｎａ 간섭의 ｒｎａ 서열 특이적인 매개체
CN100523215C (zh) 2000-12-01 2009-08-05 马普科技促进协会 介导rna干涉的小rna分子
US20020132257A1 (en) 2001-01-31 2002-09-19 Tony Giordano Use of post-transcriptional gene silencing for identifying nucleic acid sequences that modulate the function of a cell
JP2005324511A (ja) * 2004-05-17 2005-11-24 Kawamura Sangyo Kk 積層体及びその製造方法
UA93354C2 (ru) * 2004-07-09 2011-02-10 Гилиад Сайенсиз, Инк. Местный противовирусный препарат
CA2592922A1 (en) * 2004-12-29 2006-07-06 Mannkind Corporation Methods to trigger, maintain and manipulate immune responses by targeted administration of biological response modifiers into lymphoid organs
US9139850B2 (en) 2005-05-19 2015-09-22 L'oreal Vectorization of dsRNA by cationic particles and topical use
FR2885808B1 (fr) * 2005-05-19 2007-07-06 Oreal Vectorisation de dsrna par des particules cationiques et utilisation topique.
WO2007102608A1 (ja) * 2006-03-06 2007-09-13 Nanocarrier Co., Ltd. 疎水性化合物の安定化剤
AU2010232180B2 (en) * 2009-03-31 2016-09-22 Japan As Represented By The Director-General Of National Institute Of Infectious Diseases Method for prophylaxis of influenza using vaccine for intranasal administration
CN105434341B (zh) * 2015-12-22 2018-07-10 肇庆大华农生物药品有限公司 一种兽用聚腺尿苷酸注射液及其制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3582468A (en) * 1968-09-27 1971-06-01 Merck & Co Inc Recovery of double-stranded ribonucleic acid
BE793157A (fr) * 1971-12-21 1973-06-21 Beecham Group Ltd Substance antivirale
US4024222A (en) * 1973-10-30 1977-05-17 The Johns Hopkins University Nucleic acid complexes
US4415548A (en) * 1980-02-12 1983-11-15 Schmid Laboratories, Inc. Spermicidally lubricated prophylactics and method for making same
JPS57209050A (en) * 1981-06-19 1982-12-22 Jekusu Kk Condome
US4507281A (en) * 1981-10-13 1985-03-26 Exovir, Inc. Interferon-containing compositions
JPS59124514U (ja) * 1983-02-10 1984-08-22 不二ラテックス株式会社 避妊効果を確実に向上させたコンド−ム
FR2556727B1 (fr) * 1983-12-19 1990-01-19 Biostabilex Labo Pharma Nouvelles compositions therapeutiques a base d'adn a haut poids moleculaire et leur procede de preparation
CA1326450C (en) * 1985-08-26 1994-01-25 William A. Carter Modulation of aids virus-related events by double stranded rnas (dsrnas)

Also Published As

Publication number Publication date
MX12643A (es) 1993-09-01
JPH01139531A (ja) 1989-06-01
AU2053688A (en) 1989-04-20
DE3850535D1 (de) 1994-08-11
ZA885874B (en) 1989-04-26
DE3850535T2 (de) 1995-01-12
FI883734A7 (fi) 1989-02-13
CA1327001C (en) 1994-02-15
PH31174A (en) 1998-03-20
AU1736592A (en) 1992-07-30
NO883564D0 (no) 1988-08-11
IE66830B1 (en) 1996-02-07
JP2714021B2 (ja) 1998-02-16
NZ225755A (en) 1990-03-27
IL87415A (en) 1993-05-13
FI883734A0 (fi) 1988-08-11
CN1031325A (zh) 1989-03-01
PT88248B (pt) 1995-03-01
RU2061470C1 (ru) 1996-06-10
DK449988D0 (da) 1988-08-11
IE882398L (en) 1989-02-12
EP0303516B1 (en) 1994-07-06
HU209749B (en) 1994-10-28
EP0303516A3 (en) 1989-12-06
AU1001395A (en) 1995-03-09
ATE108066T1 (de) 1994-07-15
KR970007904B1 (ko) 1997-05-17
NO883564L (no) 1989-02-13
PT88248A (pt) 1989-06-30
FI883734L (fi) 1989-02-13
KR890003387A (ko) 1989-04-14
HUT47855A (en) 1989-04-28
IL87415A0 (en) 1989-01-31
EP0303516A2 (en) 1989-02-15

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment