DK45385A - Hexahydroarylquinolizin og farmaceutisk praeparat indeholdende en saadanforbindelse - Google Patents
Hexahydroarylquinolizin og farmaceutisk praeparat indeholdende en saadanforbindelse Download PDFInfo
- Publication number
- DK45385A DK45385A DK45385A DK45385A DK45385A DK 45385 A DK45385 A DK 45385A DK 45385 A DK45385 A DK 45385A DK 45385 A DK45385 A DK 45385A DK 45385 A DK45385 A DK 45385A
- Authority
- DK
- Denmark
- Prior art keywords
- hexahydroarylquinolizin
- pharmaceutical preparation
- preparation containing
- seed connection
- seed
- Prior art date
Links
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 239000000674 adrenergic antagonist Substances 0.000 abstract 1
- 102000030484 alpha-2 Adrenergic Receptor Human genes 0.000 abstract 1
- 108020004101 alpha-2 Adrenergic Receptor Proteins 0.000 abstract 1
- 230000003178 anti-diabetic effect Effects 0.000 abstract 1
- 239000000935 antidepressant agent Substances 0.000 abstract 1
- 229940005513 antidepressants Drugs 0.000 abstract 1
- -1 antidiabetics Substances 0.000 abstract 1
- 239000002220 antihypertensive agent Substances 0.000 abstract 1
- 229940030600 antihypertensive agent Drugs 0.000 abstract 1
- 229940127218 antiplatelet drug Drugs 0.000 abstract 1
- 239000000106 platelet aggregation inhibitor Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/81—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
- C07D513/14—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Hematology (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US57623384A | 1984-02-02 | 1984-02-02 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK45385D0 DK45385D0 (da) | 1985-02-01 |
| DK45385A true DK45385A (da) | 1985-09-18 |
Family
ID=24303506
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK45385A DK45385A (da) | 1984-02-02 | 1985-02-01 | Hexahydroarylquinolizin og farmaceutisk praeparat indeholdende en saadanforbindelse |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP0154142B1 (de) |
| JP (1) | JPS60188385A (de) |
| KR (1) | KR900003651B1 (de) |
| AT (1) | ATE44529T1 (de) |
| AU (1) | AU576550B2 (de) |
| CA (1) | CA1240677A (de) |
| DE (1) | DE3571438D1 (de) |
| DK (1) | DK45385A (de) |
| ES (1) | ES8609323A1 (de) |
| GR (1) | GR850211B (de) |
| IE (1) | IE850253L (de) |
| IL (1) | IL74147A (de) |
| NZ (1) | NZ210982A (de) |
| PT (1) | PT79871B (de) |
| ZA (1) | ZA85789B (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4690928A (en) * | 1984-02-02 | 1987-09-01 | Merck & Co., Inc. | Substituted hexahydro arylquinolizines as α2 blockers |
| GB8420602D0 (en) * | 1984-08-14 | 1984-09-19 | Wyeth John & Brother Ltd | Thienoquinolizines |
| DK127086A (da) * | 1985-03-25 | 1986-09-26 | Schering Corp | Substituerede 1,8-naphthyridoner, fremgangsmaader til deres fremstilling og farmaceutiske kompositioner, der indeholder disse forbindelser |
| AU582663B2 (en) * | 1985-08-10 | 1989-04-06 | John Wyeth & Brother Limited | Sulphonamides |
| US4686226A (en) * | 1985-09-03 | 1987-08-11 | Merck & Co., Inc. | Substituted benzo[b]furo- and benzo[b]thieno quinolizines |
| US4814452A (en) * | 1986-07-03 | 1989-03-21 | Merck & Co., Inc. | Enantioselective synthesis of 1,3,4,6,7,12b(S)-hexahydro-2H-benzo[b]furo[2,3-a]quinolizin-2-one |
| US4835276A (en) * | 1986-07-03 | 1989-05-30 | Merck & Co., Inc. | Preparation of n-formamidoyl[(s)-1-t-butoxy-3-methyl-2-amino)]1,2,3,4 tetrahydrobenzo [b]furo [2,3-c]pyridine and derivatives |
| NZ221485A (en) * | 1986-08-28 | 1991-04-26 | Merck & Co Inc | Hexahydroarylquinolizine derivatives and pharmaceutical compositions |
| US4831035A (en) * | 1986-08-28 | 1989-05-16 | Merck & Co., Inc. | Substituted hexahydroarylquinolizines |
| US4956365A (en) * | 1987-04-13 | 1990-09-11 | Syntex (U.S.A.) Inc. | Decahydro-8H-isoquino(2,1-g)(1,6)naphthyridine derivatives and related compounds |
| CA1321751C (en) * | 1989-02-21 | 1993-08-31 | Eugene C. Crichlow | Mechanism mediating ruminal stasis in ruminal lactic acidosis |
| WO2011067145A1 (en) | 2009-12-04 | 2011-06-09 | Nerviano Medical Sciences S.R.L. | Tricyclopyrazole derivatives |
| GB201509006D0 (en) | 2015-05-26 | 2015-07-08 | Redx Pharma Plc | Antibacterial compounds |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1470065C3 (de) * | 1961-06-19 | 1980-07-17 | Merck Patent Gmbh, 6100 Darmstadt | Verfahren zur Herstellung von Chinolizinderivaten |
| GB1435573A (en) * | 1973-05-25 | 1976-05-12 | Wyeth John & Brother Ltd | Indoloquinolizines |
| US4181657A (en) * | 1978-07-14 | 1980-01-01 | Miles Laboratories, Inc. | 2-Aminooctahydroindolo[2,3-a]quinolizines useful in treating cardiovascular disorders |
| GB2106909B (en) * | 1981-10-07 | 1984-09-19 | Wyeth John & Brother Ltd | Benzoquinolizines |
-
1985
- 1985-01-24 GR GR850211A patent/GR850211B/el unknown
- 1985-01-24 PT PT79871A patent/PT79871B/pt unknown
- 1985-01-24 IL IL74147A patent/IL74147A/xx unknown
- 1985-01-24 ES ES539799A patent/ES8609323A1/es not_active Expired
- 1985-01-25 AT AT85100732T patent/ATE44529T1/de not_active IP Right Cessation
- 1985-01-25 DE DE8585100732T patent/DE3571438D1/de not_active Expired
- 1985-01-25 EP EP85100732A patent/EP0154142B1/de not_active Expired
- 1985-01-29 NZ NZ210982A patent/NZ210982A/en unknown
- 1985-01-31 AU AU38220/85A patent/AU576550B2/en not_active Ceased
- 1985-01-31 CA CA000473300A patent/CA1240677A/en not_active Expired
- 1985-02-01 JP JP60016693A patent/JPS60188385A/ja active Pending
- 1985-02-01 DK DK45385A patent/DK45385A/da not_active Application Discontinuation
- 1985-02-01 ZA ZA85789A patent/ZA85789B/xx unknown
- 1985-02-01 KR KR1019850000635A patent/KR900003651B1/ko not_active Expired
- 1985-02-01 IE IE850253A patent/IE850253L/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR900003651B1 (ko) | 1990-05-28 |
| DE3571438D1 (en) | 1989-08-17 |
| KR850005843A (ko) | 1985-09-26 |
| GR850211B (de) | 1985-05-24 |
| PT79871B (en) | 1986-12-15 |
| ES539799A0 (es) | 1986-07-16 |
| ATE44529T1 (de) | 1989-07-15 |
| PT79871A (en) | 1985-02-01 |
| AU3822085A (en) | 1985-08-08 |
| IL74147A (en) | 1988-08-31 |
| EP0154142A1 (de) | 1985-09-11 |
| AU576550B2 (en) | 1988-09-01 |
| EP0154142B1 (de) | 1989-07-12 |
| IL74147A0 (en) | 1985-04-30 |
| JPS60188385A (ja) | 1985-09-25 |
| IE850253L (en) | 1985-08-02 |
| DK45385D0 (da) | 1985-02-01 |
| CA1240677A (en) | 1988-08-16 |
| NZ210982A (en) | 1988-04-29 |
| ES8609323A1 (es) | 1986-07-16 |
| ZA85789B (en) | 1986-09-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHS | Application shelved for other reasons than non-payment |