DK457585A - Fremgangsmaade til fremstilling af derivater af det antibiotisk virksomme cycliske peptid a-21978 c - Google Patents

Fremgangsmaade til fremstilling af derivater af det antibiotisk virksomme cycliske peptid a-21978 c Download PDF

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Publication number
DK457585A
DK457585A DK457585A DK457585A DK457585A DK 457585 A DK457585 A DK 457585A DK 457585 A DK457585 A DK 457585A DK 457585 A DK457585 A DK 457585A DK 457585 A DK457585 A DK 457585A
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DK
Denmark
Prior art keywords
peptid
procedure
producing
preparing derivatives
antibiotic effective
Prior art date
Application number
DK457585A
Other languages
English (en)
Other versions
DK457585D0 (da
DK165416C (da
DK165416B (da
Inventor
F M Huber
R L Pieper
A J Tietz
Us T E Eaton
L M Ford
Jr O W Godfrey
M L B Huber
Jr M J Zmijewski
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of DK457585D0 publication Critical patent/DK457585D0/da
Publication of DK457585A publication Critical patent/DK457585A/da
Publication of DK165416B publication Critical patent/DK165416B/da
Application granted granted Critical
Publication of DK165416C publication Critical patent/DK165416C/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Treating Waste Gases (AREA)
  • Pyrane Compounds (AREA)
DK457585A 1984-10-09 1985-10-08 Fremgangsmaade til fremstilling af derivater af det antibiotisk virksomme cycliske peptid a-21978c DK165416C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65897984A 1984-10-09 1984-10-09
US65897984 1984-10-09

Publications (4)

Publication Number Publication Date
DK457585D0 DK457585D0 (da) 1985-10-08
DK457585A true DK457585A (da) 1986-04-10
DK165416B DK165416B (da) 1992-11-23
DK165416C DK165416C (da) 1993-04-05

Family

ID=24643546

Family Applications (2)

Application Number Title Priority Date Filing Date
DK457585A DK165416C (da) 1984-10-09 1985-10-08 Fremgangsmaade til fremstilling af derivater af det antibiotisk virksomme cycliske peptid a-21978c
DK148791A DK165757C (da) 1984-10-09 1991-08-21 Biologisk ren kultur af mikroorganismen streptomyces roseosporus nrrl 15998 samt en fremgangsmaade til fremstilling af det antibiotisk virksomme a-21978c kompleks eller en eller flere af dettes faktorer co' c1' c2' c3' c4' og c5' under anvendelse af mikroorganismen

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK148791A DK165757C (da) 1984-10-09 1991-08-21 Biologisk ren kultur af mikroorganismen streptomyces roseosporus nrrl 15998 samt en fremgangsmaade til fremstilling af det antibiotisk virksomme a-21978c kompleks eller en eller flere af dettes faktorer co' c1' c2' c3' c4' og c5' under anvendelse af mikroorganismen

Country Status (27)

Country Link
EP (1) EP0178152B1 (da)
JP (1) JPH0787796B2 (da)
KR (1) KR890000800B1 (da)
CN (2) CN1013120B (da)
AT (1) ATE67788T1 (da)
AU (2) AU4837785A (da)
BG (1) BG47040A3 (da)
CS (2) CS276978B6 (da)
CY (1) CY1633A (da)
DD (2) DD238068A5 (da)
DE (1) DE3584218D1 (da)
DK (2) DK165416C (da)
EG (1) EG17619A (da)
ES (2) ES8700862A1 (da)
FI (1) FI82075C (da)
GR (1) GR852432B (da)
HK (1) HK24292A (da)
HU (1) HU196845B (da)
IE (1) IE58655B1 (da)
IL (1) IL76608A (da)
NZ (1) NZ213731A (da)
PH (1) PH21217A (da)
PL (1) PL152359B1 (da)
PT (1) PT81265B (da)
SG (1) SG3292G (da)
SU (1) SU1452484A3 (da)
ZA (1) ZA857759B (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0294990A3 (en) * 1987-06-10 1990-05-09 Eli Lilly And Company Chromatographic purification process
US4930494A (en) * 1988-03-09 1990-06-05 Olympus Optical Co., Ltd. Apparatus for bending an insertion section of an endoscope using a shape memory alloy
US4977083A (en) * 1988-04-11 1990-12-11 Eli Lilly And Company Processes for preparing A54145 compounds
DE3832362A1 (de) * 1988-09-23 1990-03-29 Sandoz Ag Neue cyclopeptolide, verfahren zu ihrer herstellung und ihre verwendung
IL150223A0 (en) 1999-12-15 2002-12-01 Cubist Pharm Inc Lipopeptides and pharmaceutical compositions containing the same
CN1423656A (zh) * 1999-12-15 2003-06-11 卡比斯特制药公司 作为抗菌剂的脂肽
US6696412B1 (en) 2000-01-20 2004-02-24 Cubist Pharmaceuticals, Inc. High purity lipopeptides, Lipopeptide micelles and processes for preparing same
US20060014674A1 (en) 2000-12-18 2006-01-19 Dennis Keith Methods for preparing purified lipopeptides
DK2379580T3 (da) 2008-12-22 2014-01-20 Cubist Pharm Inc Hidtil ukendte antibakterielle midler til behandling af gram-positive infektioner
PT2504353T (pt) 2009-11-23 2018-10-18 Cubist Pharmaceuticals Llc Composições de lipopéptido e métodos relacionados
EP2723452A2 (en) 2011-06-22 2014-04-30 Vyome Biosciences Pvt Ltd Conjugate-based antifungal and antibacterial prodrugs
IT201600127655A1 (it) 2016-12-16 2018-06-16 Gnosis Spa Processo per la purificazione di antibiotici lipopolipeptidici
CN107964557B (zh) * 2018-01-17 2020-11-20 自然资源部第三海洋研究所 一种提高芽孢杆菌抗菌脂肽产量的发酵方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4208403A (en) * 1978-10-16 1980-06-17 Eli Lilly And Company A-21978 Antibiotics and process for their production
IL68700A0 (en) * 1982-05-21 1983-09-30 Lilly Co Eli Improvements relating to a-21978c cyclic peptide derivatives and their production

Also Published As

Publication number Publication date
IE852466L (en) 1986-04-09
DD247023A5 (de) 1987-06-24
DK457585D0 (da) 1985-10-08
BG47040A3 (en) 1990-04-16
HUT39782A (en) 1986-10-29
DK148791D0 (da) 1991-08-21
DE3584218D1 (de) 1991-10-31
HK24292A (en) 1992-04-10
ES8800362A1 (es) 1987-11-01
DK165757B (da) 1993-01-11
JPS6192588A (ja) 1986-05-10
DK165416C (da) 1993-04-05
EP0178152A3 (en) 1988-11-02
FI853910A0 (fi) 1985-10-08
FI82075B (fi) 1990-09-28
DK165416B (da) 1992-11-23
PH21217A (en) 1987-08-21
HU196845B (en) 1989-01-30
CS819286A3 (en) 1992-03-18
EP0178152B1 (en) 1991-09-25
FI82075C (fi) 1991-01-10
PL255683A1 (en) 1986-07-29
ZA857759B (en) 1987-05-27
ES553603A0 (es) 1987-11-01
CS719885A3 (en) 1992-03-18
JPH0787796B2 (ja) 1995-09-27
CN1013120B (zh) 1991-07-10
PT81265A (en) 1985-11-01
CN1051200A (zh) 1991-05-08
IL76608A (en) 1991-03-10
AU4837785A (en) 1986-04-17
PL152359B1 (en) 1990-12-31
CS276983B6 (en) 1992-11-18
ES8700862A1 (es) 1986-11-16
AU5375290A (en) 1990-11-01
PT81265B (pt) 1988-02-17
IE58655B1 (en) 1993-11-03
ATE67788T1 (de) 1991-10-15
KR860003335A (ko) 1986-05-23
KR890000800B1 (ko) 1989-04-07
GR852432B (da) 1986-02-10
DK165757C (da) 1993-06-07
CN85107552A (zh) 1987-05-20
EP0178152A2 (en) 1986-04-16
CS276978B6 (en) 1992-11-18
SG3292G (en) 1992-03-20
SU1452484A3 (ru) 1989-01-15
ES547689A0 (es) 1986-11-16
IL76608A0 (en) 1986-02-28
FI853910L (fi) 1986-04-10
EG17619A (en) 1991-03-30
NZ213731A (en) 1988-04-29
CY1633A (en) 1992-11-06
DD238068A5 (de) 1986-08-06
DK148791A (da) 1991-08-21
AU634766B2 (en) 1993-03-04

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